Bone–Vascular Axis: Mechanism and Management on the Horizon

November 18, 2016 | 02:00 PM - 04:00 PM

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Basic/Clinical Science Session

Bone–Vascular Axis: Mechanism and Management on the Horizon

November 18, 2016 | 02:00 PM - 04:00 PM

Location: W181

Session Description

Vascular calcification contributes to a high burden of CVD in CKD. The pathogenesis of vascular calcification in CKD is multifactorial. Among these, the bone and vascular cross-talk plays an important role. This session discusses mechanisms of bone–vascular cross-talk, Wnt signaling pathway, and angiogenic growth factor signaling, as well as phosphate retention in the pathogenesis.

Honorary Moderator: Wadi N. Suki, MD

Session Objectives

Upon completion of this session, the participant will be able to: 1. describe new concepts in bone–vascular cross-talk; 2. explain the role of angiogenic growth factor signaling in vascular calcification; and 3. discuss recent progress in the understanding of timing and agents for phosphate control in preventing vascular calcification.

Session Acknowledgements

In celebration of its 50th anniversary, ASN thanks former ASN Councilor Wadi N. Suki, MD.

Learning Pathways

  • Bone and Mineral Metabolism
  • Chronic Kidney Disease

Corporate Support

Supported by an independent educational grant from OPKO Renal.

Moderators

  • Keith A. Hruska, MD
  • Chou-Long Huang, MD, PhD

Lectures

Angiogenic Growth Factor Signaling in the Bone–Vascular Axis Add to your Outlook, Google, Yahoo, or Apple iCal Calendar
02:00 PM - 02:30 PM
Thomas L. Clemens, PhD

Wnt Signaling in the Bone–Vascular Connection in CKD Add to your Outlook, Google, Yahoo, or Apple iCal Calendar
02:30 PM - 03:00 PM
Dwight A. Towler, MD, PhD

Role of Pyrophosphate in Vascular Calcification Add to your Outlook, Google, Yahoo, or Apple iCal Calendar
03:00 PM - 03:30 PM
W. Charles O'Neill, MD

Measurement and Clinical Consequences of Matrix Gla Protein in CKD Add to your Outlook, Google, Yahoo, or Apple iCal Calendar
03:30 PM - 04:00 PM
Leon J. Schurgers, PhD