Water (and Salt) Logged: Selective Effects of Diuretics and Aldosterone Antagonists in Hypertension

November 20, 2016 | 10:00 AM - 12:00 PM

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Clinical Practice Session

Water (and Salt) Logged: Selective Effects of Diuretics and Aldosterone Antagonists in Hypertension

November 20, 2016 | 10:00 AM - 12:00 PM

Location: W192

Session Description

Optimal use of diuretics is an integral tool for nephrologists to enhance effective BP and volume control. It is important to understand diuretic mechanisms of action and the underlying cause for the rise in serum creatinine seen with diuretic intensification. Risk/benefit ratios may differ after transplantation. New trials support additional benefits from aldosterone antagonists in treating resistant hypertension and diabetic albuminuria. This session addresses these topics.

Honorary Moderator: Donald W. Seldin, MD

Session Objectives

Upon completion of this session, the participant will be able to: 1. explain the mechanism of creatinine increase with diuretics and the implications for the kidney; 2. discuss the use of diuretic therapy in kidney transplant recipients; 3. summarize a recent trial using an aldosterone antagonist in the treatment of resistant hypertension; and 4. describe recent evidence supporting aldosterone blockade for treatment of diabetic albuminuria.

Session Acknowledgements

In celebration of its 50th anniversary, ASN thanks former ASN Councilors Laurence E. Earley, MD, and Donald W. Seldin, MD.

Learning Pathways

  • Hypertension and Cardiovascular Disease
  • Cell and Transport Physiology

Moderators

  • Andrew S. Bomback, MD, MPH
  • Branko Braam, MD, PhD, FASN

Lectures

Are Diuretics Harmful to Kidney Function? Add to your Outlook, Google, Yahoo, or Apple iCal Calendar
10:00 AM - 10:30 AM
Biff F. Palmer, MD, FASN

Use of Diuretics in Transplant Add to your Outlook, Google, Yahoo, or Apple iCal Calendar
10:30 AM - 11:00 AM
Sandra J. Taler, MD

PATHWAY-2: Use of Spironolactone in the Management of Resistant Hypertension Add to your Outlook, Google, Yahoo, or Apple iCal Calendar
11:00 AM - 11:30 AM
Bryan Williams, MD

ARTS-DM: Aldosterone Antagonists as Treatment for Diabetic Albuminuria Add to your Outlook, Google, Yahoo, or Apple iCal Calendar
11:30 AM - 12:00 PM
George L. Bakris, MD, FASN