NephSAP: Volume 5


71 0.7MB Acute metabolic acidosis is defined as a reduction in the plasma bicarbonate concentration usually associated with a decreased blood pH (acidemia), which is present for a few minutes to several days (1). The disorder is common in hospitalized patients, es
NephSAP

Volume 5, Number 1, January 2006

Fluid, Electrolyte, and Acid-Base Disturbances

Richard H. Sterns, MD and Biff F. Palmer, MD
AMA PRA Category 1 Credits™

Acute metabolic acidosis is defined as a reduction in the plasma bicarbonate concentration usually associated with a decreased blood pH (acidemia), which is present for a few minutes to several days (1). The disorder is common in hospitalized patients, es...




76 1.1MB In the last decade, great progress has been made in dissecting the molecular mechanisms of acute kidney injury (AKI; also known as acute renal failure, [ARF]); however, translation of these findings to therapeutics of clinical utility has lagged.
NephSAP

Volume 5, Number 2, March 2006

Acute Kidney Injury and Critical Care Nephrology

Paul M. Palevsky, MD and Patrick T. Murray, MD
AMA PRA Category 1 Credits™

In the last decade, great progress has been made in dissecting the molecular mechanisms of acute kidney injury (AKI; also known as acute renal failure, [ARF]); however, translation of these findings to therapeutics of clinical utility has lagged....




73 1.1MB For more than four decades clinicians and investigators recognized the need for rapid, accurate estimation of GFR, but it was not until 1976 when Cockcroft and Gault published their formula that clinicians found a fast and easy method to assess renal func
NephSAP

Volume 5, Number 3, May 2006

Chronic Kidney Disease and Progression

Chi-yuan Hsu, MD and Arrigo Schieppati, MD
AMA PRA Category 1 Credits™

For more than four decades clinicians and investigators recognized the need for rapid, accurate estimation of GFR, but it was not until 1976 when Cockcroft and Gault published their formula that clinicians found a fast and easy method to assess renal func...




96 1.6MB Over the last decade, the incidence of classic T cell–mediated acute renal allograft rejection has decreased dramatically. Despite this marked diminution of T cell–mediated rejection in the first year, longterm renal allograft survival has not improved in
NephSAP

Volume 5, Number 4, July 2006

Transplantation

John P. Vella, MD and Gabriel M. Danovitch, MD
AMA PRA Category 1 Credits™

Over the last decade, the incidence of classic T cell–mediated acute renal allograft rejection has decreased dramatically. Despite this marked diminution of T cell–mediated rejection in the first year, longterm renal allograft survival has not improved in...




59 1.1MB There is no question that hypertension increases not only the risk for progression of established chronic kidney disease (CKD) but also for cardiovascular (CV) morbidity and mortality (1). But controversy exists as to whether one or another class of antih
NephSAP

Volume 5, Number 5, September 2006

Hypertension

Stephen C. Textor, MD and George L. Bakris, MD
AMA PRA Category 1 Credits™

There is no question that hypertension increases not only the risk for progression of established chronic kidney disease (CKD) but also for cardiovascular (CV) morbidity and mortality (1). But controversy exists as to whether one or another class of antih...




101 1.1MB Diabetic and nondiabetic glomerular diseases remain the leading causes of chronic and end-stage kidney disease. As clearly articulated in this issue of NephSAP devoted to glomerular disease (November 2006), the typical classification of glomerular disease
NephSAP

Volume 5, Number 6, November 2006

Glomerular, Vascular, and Tubulointerstitial Diseases

Ronald J. Falk, MD and Richard J. Glassock, MD
AMA PRA Category 1 Credits™

Diabetic and nondiabetic glomerular diseases remain the leading causes of chronic and end-stage kidney disease. As clearly articulated in this issue of NephSAP devoted to glomerular disease (November 2006), the typical classification of glomerular disease...