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Donald E. Kohan, MD, FASN, Chair of the ASN Training Program Directors Executive Committee
Dr. Kohan—Professor of Medicine, Chief of the
Division of Nephrology
and Director of the Nephrology Training Program at the University of
Utah School of Medicine—is a member of the ASN Board of Advisors,
has served on several ASN committees, and is currently the Chair of the
Training Program Directors Executive Committee. He is also the
Assistant Dean for Graduate Medical Education at the University of
Utah, serves on the editorial board and/or as an Associate Editor of
several journals, and, until recently, served as the Chair of the VA
Nephrology Merit Review Subcommittee. Recognized for his many
contributions to the field of nephrology and author of over 80
publications, Dr. Kohan recently took a break from his busy schedule to
answer 10 questions for this edition of Renal Express.
You recently completed
your first year as Chair of the Training Program Directors (TPD)
Executive Committee. Can you tell our readers what this group does and
what the group is working on currently?
The TPD Executive Committee represents U.S. nephrology training
programs. Our mission is to help promote improvements in the quality of
all aspects of nephrology training. Our current direction was largely
defined during the Nephrology TPD Retreat held last year in Chicago. In
addition to instituting the Match, we are involved in the following
activities:
1) Development of an in-training examination for all renal fellows.
This effort was spearheaded by Mark Rosenberg and is now under the
leadership of Mitch Rosner. The questions will be developed by a panel
of volunteer experts in nephrology working closely with the National
Board of Medical Examiners. The first test should be available in 2009
or 2010 and will be administered electronically.
2) Establishment of new RRC guidelines. We have a TPD subcommittee
working with the ACGME to create revisions to the current RRC
guidelines. We are greatly interested in simplifying the requirements,
while insuring that they adequately address training needs.
3) Creation of a toolkit to assist in fellow teaching. This TPD
subcommittee is collecting teaching material from as many training
programs as will contribute, then sorting through and arranging this
material in a way that will facilitate nephrology teaching. In
addition, new teaching techniques, evaluation methodologies, and
standardized curricula are being addressed. We greatly welcome
participation by TPDs - there is more than enough work for all of us to
do!
4) Improved use of web-based methods to facilitate fellow training and
TPD communication.
5) Creating a session or sessions at ASN Renal Week devoted to
improvements in nephrology fellow education. The goal is to have
abstracts on educational instruments and advances submitted, reviewed,
presented at the meeting, and ultimately published.
There will be other activities as well, but these are the major
initiatives for now.
The overwhelming majority
of training programs have agreed to take part in the National Resident
Matching Program (NRMP) Specialties Matching Service (SMS), which will
begin in 2009. What is SMS and how will it benefit training programs?
The SMS administers the match that is used by almost all school of
medicine departments; it also administers the match for 12 internal
medicine subspecialties. The principle of the nephrology match is
essentially the same as that for other matches. Applicants and programs
rank their selections, followed by a formal Match Day on June 18, 2008,
for positions starting July 1, 2009. There are many advantages to the
match, including creation of an impartial venue for matching programs'
and applicants' preferences, permitting applicants to choose programs
without undue pressure, allowing increased time to decide (rank order
lists are not due until June 4, 2008), and establishment of a uniform
offer/acceptance date. I think a testament to the benefits of the match
is that greater than 90% voted in favor of the match by nephrology
training programs.
Your ambitious agenda and
intrepid leadership have impressed Fellowship Training Program
Directors from across the country. What’s the secret of your success?
What drives your desire to “get things done?”
I'm not sure about intrepid leadership, but I think the key to success
is getting as many people as possible involved, giving them ownership,
and making sure that all discussions are held, and decisions made, in
an open forum that involves as many people as possible. What we do as
TPDs is very difficult with all of the rules and regulations, however,
many of the solutions to our current challenges are out there. It
mainly requires getting people to freely share their ideas and
experiences, as well as seeking input even from those outside of
nephrology. As for motivation, I have yet to meet a nephrology TPD who
wasn't motivated, as I am, to make fellowship training a great
educational experience for faculty and trainees alike.
You completed your
fellowship training at the Washington University School of Medicine in
St. Louis, Missouri. What is your most memorable educational
experience?
It wasn't classical medical knowledge, but I most remember my former
Division Chief, Dr. Saulo Klahr, one of the smartest individuals I've
ever met, sitting me down in his office and asking me about career
plans. I was a bit nervous about succeeding in research even though I
had a number of research ideas that interested me. Dr. Klahr asked "Do
you want to be a bricklayer or an architect?" I don't think he meant
anything derogatory about making contributions while working in the
background; rather, he was saying that if you have potential, don't be
afraid to try to reach for something greater. I would give the same
advice to many trainees and junior faculty intimidated by a research
career, but clearly with a strong curiosity and intrinsic ability.
Why did you decide to be a
nephrologist?
I originally did a PhD in physiology and wound up studying the nephron
sites responsible for escape from the sodium-retaining effects of
mineralocorticoids. After I got my MD, it was a natural progression to
do nephrology.
What are your research
interests? Can you give us a lay account of your research?
My laboratory studies the regulation of renal collecting duct Na and
water transport. We utilize gene targeting strategies whereby we
disrupt target genes selectively within the collecting duct in order to
determine their role in normal renal physiology and in pathologic
conditions. We are particularly interested in the role of the
endothelin and nitric oxide systems in hypertension and have found that
mice lacking collecting duct endothelin are markedly hypertensive, and
that the endothelin effect is mediated by nitric oxide. In
collaboration with Drs. Matt Breyer's and Tianxin Yang's laboratories,
we have determined that collecting duct PPARgamma is responsible for
the edema due to thiazolidinedione treatment. We are currently
examining the role of individual adenylyl cyclases in regulating
collecting duct, as well as whole nephron, function.
What advice would you give
a young scientist in your field regarding his/her future career?
Would it be different for male as opposed to female students?
I think they should focus on the optimal way to get EMS, regardless of
gender—environment, mentorship and support. Several great articles
have been written by prominent scientists, including Nobel laureates
and members of the National Academy of Sciences, about what is required
to be successful as a physician scientist. A scientifically-nourishing
environment is critical at all stages, but particularly early in one's
career. Adequate protected time and financial support goes without
saying. However, the biggest piece that is most often missing, and the
one repeatedly emphasized by visionaries in science, is mentoring. This
can be done by any number of people; the key is having a mentor who
provides guidance on applying for grants, strategizing on how to
operate your research program, identification of potential
collaborators or just good scientists to learn from, etc. The
mentorship should continue for many years, not just having someone
point you in the right direction and let you go.
What might be done to
increase the interest of medical students in pursuing careers in
nephrology?
This is a very difficult question. Fewer medical students are going
into internal medicine because of perceived issues with lifestyle,
income and the evolution of the general internist/hospitalist schism.
Many students are intimidated by the complexity of nephrology. I think
the major thing I would work on is stimulating an interest in
nephrology through exposure to renal-related research. Summer programs,
such as the one Dr. Mark Zeidel is working on to expose renal fellows
to renal research techniques, could be applied to medical students. Why
not have medical students participate in renal camp, doing an
experiment examining ion transport using a patch clamp apparatus or a
Ussing chamber, studying renal clearance in a rat, or doing other renal
studies? While recruiting more nephrologists is important, I think
focusing on getting more MDs interested in renal research is really the
key to the future of our subspecialty. I also think that we should
extend these activities to the undergraduate and high school level—in
effect, "imprinting" Nephrology research!
Other than being a
successful nephrologist, what would you most like to be remembered for?
Other than the obvious things (a good husband, father, son and friend),
I care the most about education. I think the contributions of the
clinicians and scientists whose training I impact will be far greater
than any individual clinical or research accomplishments of my own.
How do you spend your free
time?
I am a bit of an adventurer. I enjoy, along with my family, scuba
diving (particularly cave or cenote-diving in the Yucatan), white-water
rafting through deep canyons in the West, kayaking in the Sea of
Cortez, alpine skiing (Utah snow is the best), and traveling abroad.
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Senate Finance
Committee discusses Medicare Bill
To discuss
provisions of a Senate Medicare bill that is forthcoming this spring,
the Senate Finance Committee held a meeting with the physician
community and other clinical groups on Friday, April 11, 2008. The meeting gave Committee Chair Max Baucus (D-MT) an opportunity to relay his priorities for the Senate Medicare bill and explore ways that
his office and health care practitioners can work together to achieve
the best possible outcomes for Medicare beneficiaries. ASN
- represented by Paul Smedberg, Director, Policy & Public Affairs -
attended the meeting along with 35 other
representatives.
Senator Baucus plans to have a Medicare bill to the Senate floor by
mid-May 2008, and hopes of passage by June 30, 2008. The bill's
major provision is a sustainable growth rate (SGR) fix for 18
months. His draft SGR proposal would increase physician
reimbursement by 1.1 percent at a minimum and cost approximately $8
billion over five years. Ultimately, the senator wants to
re-formulate SGR so the Senate Finance Committee does not need to
replicate this exercise every year.
In addition to the SGR fix, the senator's Medicare bill will likely
include (but is not limited to) physician quality initiatives,
provisions to address the current state of primary care medicine,
enhancements to a Medical-Home demonstration project, and possible
reform to payments for end-stage renal disease (ESRD). Senior committee staff who joined Senator Baucus for the meeting
indicated that the ESRD reform provisions are comprehensive and will
likely include a phase-in of an expanded ESRD bundled payment.
According to Senator Baucus, any Senate Medicare bill will need 60
votes if it is to have any chance of passage. He also
stated that negotiations are currently underway with the House of
Representatives to draft a Medicare bill both chambers of Congress can
support. In addition to keeping its members informed about
this legislation, ASN plans to work with the rest of the renal
community concerning these issues.
Clinical
Research Forum Focuses on Decline in Physician-Scientist Workforce
The Clinical Research Forum (CRF)—a consortium of
47 medical schools and teaching hospitals dedicated to sharing best
practices in clinical research and advocating for support of the
broader interests and needs of clinical research—held its annual
meeting Thursday and Friday, April 10-11, 2008, in Washington,
DC. Presenting on behalf of the Association of Professors of
Medicine (APM) Physician-Scientist Initiative, Andrew I. Schafer, MD,
proposed four recommendations for revitalizing the physician-scientist
workforce. APM suggests allocating resources to repair the
“leaking” physician-scientist pipeline, enhancing mentoring programs,
promoting the advancement of female investigators, and strengthening
efforts to support investigators with a “more enduring commitment to
research careers.” The APM Physician-Scientist Initiative—which
was partially funded by the American Society of Nephrology—is a
“long-term initiative to identify, develop, and implement substantive
and practical solutions that will ensure the survival, growth, and
diversity of the physician-scientist workforce.
ASN Research Policy Coordinator Allison Haupt represented the Society
at the CRF Annual Meeting, where participants also discussed the
viability of creating a clinical trials curriculum, efforts by
BlueCross BlueShield to support comparative effectiveness research, the
decline in interest in primary care, and ways to advocate for increased
funding for the National Institutes of Health's Clinical and
Translational Research Awards. For more information on the
meeting, the Clinical Research Forum, and its activities, please visit www.clinicalresearchforum.org.
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ASN Committee Report
The Dialysis
Advisory Group (DAG) focuses on the practical provision of care to
patients with ESRD as well as the methods to support nephrologists
caring for those patients.
Recently, DAG published a series of articles in the Clinical Journal of the American Society
of Nephrology (CJASN). DAG polled the ASN membership to identify
key areas of primary care that the membership provides to their
dialysis patients. Leaders in the each of these areas (which
included cancer screening, mental health, and hormone replacement) were
then invited to submit review articles related to their area of
expertise, with a practical focus on how to provide care for the
patient with concurrent kidney disease.
In 2008, DAG turned its attention to two different areas:
education and facilitation of research. Recognizing that there
are certain core components to the teaching of the logistics and
physiology of the provision of dialysis, DAG will assist the Fellowship
Training Program Directors Executive Committee in drafting educational
material that may be utilized to meet individual teacher needs.
Further, DAG seeks to understand the logistics of initiating a research
project in patients with end-stage renal disease and facilitating
efficiencies that can be found at a national level.
Lynda A. Szczech, MD, FASN
Duke University Medical Center
Chair, Dialysis Advisory Group
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JASN
Donor
Age Linked to Aortic Stiffening
Transplantation of kidneys from older donors is followed by increased
stiffening of the recipient's aorta - which may help to explain the
higher rates of cardiovascular disease and death in patients receiving
kidneys from "expanded criteria" donors. TOC; Full
Study
NephSAP
NephSAP Core Knowledge Questions
NephSAP provides a new program to help trainees and others prepare for
ABIM certification and maintenance of certification.
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ASN Reminders
International
Society of Nephrology (ISN) Nexus Symposium on Transplantation and the
Kidney
Abstract
submission deadline extended to April 30, 2008
This
symposium will take place September 25-28, 2008, in Rome, Italy. Among
the list of topics to be considered and discussed:
Immunopathogenesis
of CAD, Risk Factors, Pathology, Immunosuppression, and Novel
Strategies for Management.
To learn more about the program and submit your abstract before April
30, click
here.
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Retirements
Jack W. Strandhoy,
PhD, will retire as Professor Emeritus of Physiology and Pharmacology
from the Wake Forest University
School of Medicine on July 1, 2008. He has been an ASN member of
30 years.
Hans Erik Hansen,
MD, DMSc, Chief Physician in Nephrology, Associate Professor in
Medicine at Skejby University Hospital,
Aarhus, Denmark, retired on December 31, 2007.
Employment/Appointments
Josephine P. Briggs,
MD, was named Director of the National
Institutes of Health’s National Center for Complementary and
Alternative Medicine (NCCAM).
Joel Topf, MD, has
joined the medical staff at Botsford
Hospital.
Aubrey R. Morrison,
MD, FASN, became Program Director of the Washington University Renal Training
Program.
John W. O'Bell, MD,
has been hired as Associate Fellowship Director at Rhode Island Hospital.
Jochen Reiser, MD,
PhD, has been hired as chief of the Division of Nephrology at the University of Miami Leonard M.
Miller School of Medicine.
David Altshuler,
MD, PhD, an Associate Professor of Genetics and Medicine at the Harvard University Medical School
and a member of the Diabetes Unit and Department of Molecular Biology
at Massachusetts General Hospital was appointed to the Advisory Council
of the National Institute of Diabetes and Digestive Kidney Diseases.
Honors
Wendy Hoy, MD, of
the University of Queensland
has been awarded the United States National Kidney Foundation (NKF)
International Distinguished Medal for 2008. The Medal was established
to honor the achievement of individuals who have made significant
contributions to the field of kidney and related chronic disease.
David J. Salant,
MD, Chief of Nephrology at Boston
Medical Center and a professor of medicine, pathology and
laboratory medicine at Boston
University School of Medicine, has received the 2008 Outstanding
Physician in Nephrology Award from the National Kidney Foundation of
Massachusetts, Rhode Island, New Hampshire and Vermont.
Please send ASN Member
News to bcarver@asn-online.org
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