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Dear ASN Members,
In what has become an annual June tradition for ASN, ASN President
Peter S. Aronson, MD, FASN, invited me, as Chair of the Society’s
Program Committee, to write this month's Renal Express "President's
Message" and provide an update regarding Renal Week 2008, which will
take place at the Pennsylvania Convention Center in Philadelphia, PA,
from November 4-9. The theme of this year's meeting is "Translating
Basic and Clinical Science into Advances in Prevention and Treatment of
Kidney Disease."
This year's meeting will feature four scientific themes: Renal
Immunology and Transplantation, Cardiovascular Disease and Chronic
Kidney Disease (CKD), Stem Cells and Kidney Development, and Epithelial
Transport and Cell Biology. Each theme will be the focus of a
Meeting-Within-a-Meeting (MWM), the format that premiered at last
year’s ASN meeting. Each MWM consists of scientific symposia and free
communications (oral abstract sessions) that are related to a theme and
are held in the same room throughout Renal Week.
Each featured
theme will be highlighted by a State-of-the-Art lecture that is
designed to appeal to the entire ASN membership.
- At the opening Plenary
Session on Thursday, November 6, Diane J. Mathis, PhD, from the Joslin
Clinic and Harvard Medical School will discuss molecular mechanisms of
autoimmunity.
- During the plenary
session Friday, November, 7, Eric Olson, PhD, from the University of
Texas Southwestern Medical Center, will discuss the emerging field of
micro RNAs and their role in cardiovascular disease.
- On Saturday, November 8,
Janet Rossant, PhD, from the Hospital for Sick Children and University
of Toronto, will discuss stem cells and the future of medicine.
- Richard P. Lifton, MD,
PhD, of Yale University School of Medicine will give the closing
Plenary Session lecture on Sunday, November 9, on the genetics of
hypertension and electrolyte abnormalities.
In addition to the MWMs, the members of the Program Committee and the
Postgraduate Education Committee (which is chaired by Mark E.
Rosenberg, MD) have worked together to develop clinical and basic
science symposia and clinical nephrology conferences that address a
wide variety of key issues in kidney biology and disease. Topics range
from the biology of iron to non-adherence, and include sessions on
nephrogenic systemic fibrosis, organ allocation, and anemia management
among many other subjects. Each day's program provides a number of
choices designed to appeal to a broad spectrum of clinical and
scientific interests.
I am particularly grateful to you, the members of ASN, for continuing
to submit your best clinical and basic research for presentation at
Renal Week. This year, the Program Committee implemented a few changes
in the abstract categories in response to ongoing trends in nephrology
research. First, the abstract category for CKD was expanded into three
categories. The committee developed a new abstract category for
nephrology education in recognition of the need for scientifically
rigorous approaches to train nephrology fellows and clinicians. Also
new this year will be a separate abstract deadline for late-breaking
clinical trials. The deadline for these abstracts is Wednesday,
September 24; ASN will announce that the submissions are due in an
email and postcard sent to ASN members in August. Selected abstracts
will be presented in a special late-breaking clinical trial session and
published online and in a future issue of the Clinical Journal of the
American Society of Nephrology.
Later this month, ASN will mail the Preliminary Program for Renal Week
2008 to ASN members and all Renal Week 2007 participants. The
Preliminary Program includes information on the scientific program,
registration, hotel reservations, travel, local Philadelphia
attractions, and more. ASN will also post the program with complete and
frequently updated information on the symposia and clinical nephrology
conferences on the ASN website at www.asn-online.org.
In October, the ASN website will provide the abstracts in an online
searchable format.
I look forward to seeing you in Philadelphia!
Sincerely,

Peter Igarashi, MD, FASN
2008 Chair, ASN Program Committee
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ASN Sponsors
Physician-Scientist Initiative, APM Releases Recommendations
The
Association of Professors of Medicine (APM) released its report, "Recommendations
for Revitalizing the Nation’s Physician-Scientist Workforce,"
Friday, May 23, 2008. An overview of the first phase of the APM
Physician-Scientist Initiative, the report presents 30 recommendations
for supporting and invigorating the physician-scientist workforce as
proposed at the association’s November consensus conference. To support
efforts to address the alarming decline in the physician-scientist
workforce, ASN contributed to the first phase of the APM
Physician-Scientist Initiative. Several ASN members participated in
last fall’s consensus conference.
The four major recommendations stemming from the conference,
"Revitalization of the Nation’s Physician Workforce," are:
- Attention and resources
should be directed at repairing the "leaking" physician-scientist
pipeline.
- Major changes should be
made to the contemporary approach to mentoring physician-scientists.
- Institutions should
proactively promote the advancement and minimize the attrition of women
in physician-scientist careers.
- The physician-scientist
workforce should be strengthened by earlier and more coordinated
efforts to identify and prepare successful future investigators with a
more enduring commitment to research careers.
Along with the consensus
conference and recommendations, the first phase included a series of
surveys and focus groups directed at assessing the problems impacting
physician-scientists, with particular attention given to the next
generation of investigators. According to APM, it is “currently
planning phase two of the initiative [led by Principal Investigator
Andrew I. Schafer, MD, Chair of the Department of Medicine at Weill
Cornell Medical College] to encourage medical schools, teaching
hospitals, universities, and federal and private organizations that
fund research to implement the recommendations. Next steps will include
convening leaders in institutions and clinical departments to
coordinate an action plan that will expand, revitalize, and diversify
the physician-scientist workforce.
ASN
Examines the Patient-Centered Medical Home
In response to the increasing interest in the
concept of a Patient-Centered Medical Home (PCMH), ASN has formed a
task force, chaired by Thomas D. DuBose, Jr., MD, to determine how the
PCMH may affect the practice of nephrology. The American College of
Physicians (ACP), the American Academy of Family Physicians, the
American Academy of Pediatrics, and the American Osteopathic
Association define the PCMH as "…a team-based model of care led by a
personal physician who provides continuous and coordinated care
throughout a patient's lifetime to maximize health outcomes."
Reporting to the ASN Public Policy Board, the ASN PCMH Task Force has
drafted four possible scenarios to help clarify how a nephrologist will
participate within the framework of a patient’s "medical home." The
four scenarios address patients with early stage 3 chronic kidney
disease (CKD); stage 4 CKD; end-stage renal disease (dialysis); and an
uncommon but complex disorder that requires the nephrologist to provide
comprehensive care. Each scenario raises questions about the role of
the nephrologist, and the task force will discuss these issues with
Michael Barr, MD, ACP Vice President for Practice Advocacy &
Improvement during a meeting later this month.
In addition to Dr. DuBose, the ASN PCMH Task force includes: Mary
(Tessie) T. Behrens, MD, Arnold S. Berns, MD, Connie L. Davis, MD,
Thomas H. Hostetter, MD, Paul E. Klotman, MD, and Lynda A. Szczech,
MD. Several other ASN members are contributing to the task
force’s discussions.
For more information about PCMH, please view ACP’s
summary. To learn more about the task force, please contact
ASN Senior Policy Coordinator Susan Owens at 202-416-0668 or sowens@asn-online.org.
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13th Annual Board
Review Course & Update
Registration for the 13th Annual ASN
Board Review Course & Update (BRCU) is now open. The BRCU will
once again take place in San Francisco, CA. Previous courses were
hugely successful, and those preparing for the American Board of
Internal Medicine’s (ABIM’s) Maintenance of Certification (MOC)
examination are increasing registration numbers each year. Please register
early to ensure a place in the 2008 course. The pre-registration
deadline is Friday, August 8, 2008.
Onsite registration may not be possible, due to space limitations.
The timing of BRCU in late August maximizes participants' readiness for
the ABIM certification and MOC examinations, which take place November
24, 2008 (also May 12, 2009, for MOC only). After completion of
the course and the self-assessment test, participants have nearly three
full months to fill in any newly discovered gaps in their knowledge.
This course provides a timely, comprehensive, and thorough update for
the practicing nephrologist.
The Palace Hotel is the location for the ASN BRCU. This historic
landmark provides the atmosphere and quality service you would expect
from an elegant hotel. Its central location is steps away from Union
Square, the BART (Bay Area Rapid Transit), and the cable cars, making
the Palace a perfect base for your extracurricular adventures. BRCU
concludes at the start of the Labor Day weekend, which means
participants can plan a holiday vacation in the Bay Area.
ASN has reserved a block of rooms at a reduced rate at The Palace
Hotel. ASN recommends that you make your online
hotel reservation as soon as possible to ensure your guest room at
the special rate of $234.00 plus taxes. The deadline for hotel
reservations is Thursday, July 31,
2008. The hotel may not be able to honor the lower ASN rate
after this date; however, rooms may still be available.
The ASN's Board Review Course event travel coordinator, Apollo Travel,
has negotiated special air travel discounts for our meeting attendees. Hotel
and Travel Information are available here.
Tuition
& Registration
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Tuition
Amount
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ASN
Active/Corresponding Member
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$1,100
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ASN Fellow/Associate
Member
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$900
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Nonmember
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$1,350
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Nonmember Fellow
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$1,050
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To register for the Board Review Course & Update, visit the registration
website. Online registration accepts American Express, MasterCard,
or Visa.
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Report of the ASN
Basic Science Committee
The ASN Basic Science Committee is responsible for
developing basic science educational programs, such as ASN's Advances
in Basic Science Conference (ARC); developing and hosting the basic
science evenings during Renal Week; recommending initiatives to the ASN
Council that will enhance the activities of basic scientists in the
Society; and responding to special requests by the council in areas
related to basic science in nephrology.
The committee’s recent activities have focused on programming
responsibilities. The schedule, speaker list, and topics have been
finalized for the 2008 ARC: Human
Disorders of Protein Processing: Mechanisms, Consequences and
Therapeutic Implications, which will bring together
internationally recognized scientists with expertise that ranges from
protein folding dynamics and intracellular trafficking to renal folding
diseases and drug development. The committee submitted and received an
NIH R13 (small conference) Grant that will be used to provide travel
awards for participants.
Recently, the committee selected, in conjunction with the ASN Program
Committee, topics for two basic science evening sessions during Renal
Week 2008. These sessions are designed to be more technically oriented
for the basic scientist. The 2008 topics are:
- Chromatin Structure and
Transcriptional Control
- ChIP assays,
ChIP-on-ChIP, new high throughput techniques for performing ChIP assays
on multiple genes, Capturing Chromosome Conformation (3C assay).
- RNAi Techniques
- Introducing into cells,
achieving good expression levels and good knock down, vectors that
result in good knock downs, verification, specificity, and appropriate
controls to be performed.
The committee looks forward to
seeing everyone at these programs. And, don’t forget to apply
for one of the travel awards to attend the ARC.
Pat Preisig, PhD
Yale University
Chair, ASN Basic Science Committee
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JASN
Hidden
Heart Condition Increases the Risk of Death in Patients Waiting for
Kidney Transplants
An often asymptomatic condition—systolic dysfunction, or decreased
pumping of the heart—poses an increased risk of death for patients on
kidney transplant waiting lists. Study findings reveal that a clinical
indicator beyond well-known risk factors for cardiovascular mortality
should be considered when caring for patients waiting for kidney
donations. The study also suggests that changes in organ allocation
policies may be warranted. TOC;
Full
Study
Medical Research is Essential to
Improving The Economy and Bettering Lives: Now is Not the Time to
Stifle the Funding of Science
Health care in the United States is expensive, but its funding is
crucial because it also is a major contributor to the economy and can
better lives. This essay claims that because of the cost of health
care, this is not time to shrink the budget at the NIH, which funds
medical research that leads to potentially curative therapy. TOC; Full
Study
Evidence Lacking on Health
Benefits of Drinking Lots of Water
A recent look at what is known about the health effects of drinking
water reveals that most supposed benefits are not backed by solid
evidence. The findings indicate that most people do not need to worry
about drinking their recommended eight glasses of eight ounces ("8x8")
of water per day. TOC; Full
Study
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ASN Reminders
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