ASN represents more than 21,000 kidney health professionals working to help people with kidney diseases and their families. Comprised of all of ASN's focus areas, the ASN Alliance for Kidney Health allows the society to continue its growth and work towards the goal of a world without kidney diseases.
The latest Nephrology Self-Assessment Program (nephSAP) issue, Volume 22: Issue 4 (Feb 2024): Pregnancy and Kidney Disease is now available online.
RE: Volunteer by May 8 to serve as a case report reviewer for Kidney Week 2024! 2 hours ago
Thanks for your response. Kindly give me an idea of your scoring criteria. Thank you
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RE: Possible hydralazine associated ANCA vasculitis/lupus,/treat or not 11 hours ago
Thanks Dr Venkat and Dr Nauman Dr Venkat patient has been on spironolactone 50 mg since 9/2023 Dr Nauman her DSDNA. Was negative ----------------...
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RE: Kidney Showing Severe Arteriosclerosis With Patient Has No HTN 11 hours ago
Moderate to severe arteriosclerosis can be seen in kidney biopsies with familial dysautonomia (characterized by low blood pressure, impaired kidney...
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RE: Kidney Showing Severe Arteriosclerosis With Patient Has No HTN 12 hours ago
No diabetes and no clinical signs suggestive of scleroderma also his BP has been very low in the clinic --------------------------------- Ali Ayes...
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Request for Expert Opinions on Chronic Interstitial Nephritis Management 12 hours ago
Patient Profile: - Age/Sex: 60-year-old South Asian male - Past Medical History: - Type 2 Diabetes Mellitus (managed with insulin) - Depression/A...
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RE: Kidney Showing Severe Arteriosclerosis With Patient Has No HTN 13 hours ago
Normal kidney aging can be associated with arterio-and arteriolo- sclerosis, even in the absence of elevated blood pressure but this degree of prot...
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RE: Proteinuria, hypoalbunimia management during pregnancy 13 hours ago
Dr Ahmed if Cr does not come down after cessation of CNI, at what point would you consider delivery. ------------------------------ Awais Nauman ...
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RE: Kidney Showing Severe Arteriosclerosis With Patient Has No HTN 13 hours ago
Senile arteriolosclerosis ------------------------------ Awais Nauman HMC Doha ------------------------------
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RE: Proteinuria, hypoalbunimia management during pregnancy 13 hours ago
Thanks everyone. Dr Rodby, after the urine being negative for hematuria, we found more analyses showing micro-hemaruria. will stop CNI as...
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Kidney Showing Severe Arteriosclerosis With Patient Has No HTN 13 hours ago
Would Appreciate your input : 78-year-old male patient was referred to me by my clinic 6 months ago for abnormal renal function test, his creatini...
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RE: Possible hydralazine associated ANCA vasculitis/lupus,/treat or not 14 hours ago
Is it Hydralazine induced Lupus Interstitial Nephritis rather than Hudralazine induced AAV associated Interstitial Nephritis? In this study 5 pati...
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RE: Volunteer by May 8 to serve as a case report reviewer for Kidney Week 2024! 15 hours ago
Thank you for your interest in reviewing trainee case reports! For time commitment, ASN's goal is to assign no more than 60 case reports (abstracts...
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RE: Volunteer by May 8 to serve as a case report reviewer for Kidney Week 2024! 15 hours ago
Good evening. I am willing to serve as a reviewer. Thank you for the opportunity.Dr. Onu Ugochi Chika
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RE: Refractory Hypercalcemia of Malignancy with hypophosphatemia (elevated 1,25-OH VitD and PTHrP) 17 hours ago
Regarding the mechanism(s) of hypercalcemia and hypophosphatemia in this patient: 1. It has been suggested that hypercalcemia may directly cause re...
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RE: Volunteer by May 8 to serve as a case report reviewer for Kidney Week 2024! 18 hours ago
Hi What is the time commitment and expectations on this? Thanks ------------------------------ Jose Agraz PhD postdoctoral fellow university ...
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RE: Possible hydralazine associated ANCA vasculitis/lupus,/treat or not 18 hours ago
I assume spironolactone is being used for BP control since proteinuria is not severe. What is the dose of spironolactone? Some of the recent increa...
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RE: Refractory Hypercalcemia of Malignancy with hypophosphatemia (elevated 1,25-OH VitD and PTHrP) 19 hours ago
Agree with Dr Rodby's comments. I would not use fluconozole as elevated 125 would like increase and not decrease the phosphate. It could be from PT...
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RE: Possible hydralazine associated ANCA vasculitis/lupus,/treat or not 19 hours ago
Thanks a lot Dr Glassock and Dr Rudby Very helpful No Eosinophilia IF on Bx negative Don’t have IgG4 will check I was thinking to treat with ste...
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RE: Refractory Hypercalcemia of Malignancy with hypophosphatemia (elevated 1,25-OH VitD and PTHrP) 19 hours ago
That 1-25 is crazy high but I dont see how that causes the hypoPO4 and PO4 wasting. FGF23 is rare in breast cancer but not unheard of https://p...
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RE: Refractory Hypercalcemia of Malignancy with hypophosphatemia (elevated 1,25-OH VitD and PTHrP) 20 hours ago
You might ask your Medical Oncologists if a MAP kinase inhibitor (like Trametinib ) would have any palliative value as these agents may help to all...
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RE: LN not in remission 20 hours ago
Do you? 1) rebiopsy and see if that helps you decide - I think you will find a mixture of old and new MGN, I doubt it will be only old MGN as pro...
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RE: Access to dialysis morbid obese non mobile 20 hours ago
Thanks Roger for asking. We have done home training before in circumstances like this, but in terms of scheduling it takes a nurse out of the uni...
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RE: Possible hydralazine associated ANCA vasculitis/lupus,/treat or not 20 hours ago
what an odd ending to what I though was an obvious story. The pan-serology is typical for hydralazine but the pathology and urine are not, at ...
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RE: Proteinuria, hypoalbunimia management during pregnancy 20 hours ago
I applaud my wiser colleagues on this one. I will be shocked it the Genetic testing does not confirm a COL4A5 mutation. And even if it doesn't, t...
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RE: Proteinuria, hypoalbunimia management during pregnancy 23 hours ago
I would stop both steroids and CNI.This is most likely X-linked Alport syndrome, as has been suspected all along.. . ---------------------------...
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RE: Proteinuria, hypoalbunimia management during pregnancy 1 day ago
Kidney biopsy results are attached. COL4 mutation result pending. proteinuria down from 6.95 (2 weeks ago to 4.68 gm/24 hour but serum Album...
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RE: Possible hydralazine associated ANCA vasculitis/lupus,/treat or not 1 day ago
No hematuria, non-glomerular proteinuria , impaired GFR and mainly interstitial nephritis on kidney biopsy. Serology and C levels suggest Hydralazi...
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RE: Volunteer by May 8 to serve as a case report reviewer for Kidney Week 2024! 1 day ago
I can act as a reviewer if you still need! Thanks, Arti ------------------------------ Arti Dhoot MD Winnipeg MB (647) 455-1601 --------...
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RE: LN not in remission 1 day ago
I agree that value of IS is not clear at this time. Looks like burned-out disease with residual glomerular damage. ------------------------------...
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RE: Refractory Hypercalcemia of Malignancy with hypophosphatemia (elevated 1,25-OH VitD and PTHrP) 1 day ago
I have had success using ketoconazole in situations like this where " non-renal" CYP27B1 function ( ex. Sarcoid macrophage production of 1,25 di-oh...
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Possible hydralazine associated ANCA vasculitis/lupus,/treat or not 1 day ago
I would appreciate expert input on the 66 year-old Caucasian female with no history of smoking History of hypertension, she tell me controlled firs...
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RE: LN not in remission 1 day ago
The pathogenesis of sub-epithelial ED deposition of Ig in "pure" Lupus MN is unknown and Laboratory findings suggestive of inflammation are general...
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Refractory Hypercalcemia of Malignancy with hypophosphatemia (elevated 1,25-OH VitD and PTHrP) 1 day ago
I have recently been consulted the management of hypercalcemia of malignancy and am hoping for any advice on a concurrent hypophosphatemia. She's...
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RE: LN not in remission 1 day ago
At the moment there is no evidence of efficacy for Belimumab in Pure Class V LN, but all studies so far are likely underpowered to show such an eff...
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RE: LN not in remission 1 day ago
In the attached trial 16% of the patients were class V membranous, and was not powered for that subgroup, but in a secondary analysis this is somew...
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RE: LN not in remission 1 day ago
Any experience with the use of belimumab in combination with mycophenolate in lupus membranous nephritis? ------------------------------ Mohamed ...
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RE: LN not in remission 1 day ago
I have no idea what is the cause of "calcium" depi9 in the kidney- Has he had a colonoscopy prep with phosphate enemas in the past ? Are the deposi...
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RE: LN not in remission 1 day ago
In membranaous LN immune complex formation occur in situ and AutoAb targets are resident podocyte antigens as opposed to proliferative LN where cir...
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RE: LN not in remission 1 day ago
Antibodies triggered by "certain cell-nucleus-remnants" had caused full house AB trapping in GBM + TBM [glom + prox tub] War appears to be ove...
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RE: LN not in remission 1 day ago
I realize that a kidney biopsy was performed only 5 months age, but does anyone think that a repeat kidney biopsy would be of assistance in making ...
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RE: LN not in remission 1 day ago
As already pointed out, the key issue here is whether the patient is in remission or not. His proteinuria has been reasonably stable but the last t...
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RE: LN not in remission 2 days ago
Thanks Dr. Hirsch for your very astute post concerning this vexing issue: Specifically how should one interpret persistent non-nephrotic prote...
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RE: LN not in remission 2 days ago
Following up on "a lot of medicine" and the possible evolution into irreversible podocyte injury without much ongoing immunologic activity....What ...
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RE: LN not in remission 2 days ago
Dr. Rodby- interesting opinion. Would you still recommend a switch to RTX if a repeat biopsy showed only old electron lucent deposits and a lot of ...
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RE: LN not in remission 2 days ago
That is a lot of medicine for Class V lupus that is non-nephrotic: Cellcept/voclosporin/Plaquenil/Prednisone , invokana/losartan/diltiazem Creat ...
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RE: LN not in remission 2 days ago
Difficult question as the definition of remission is not well standardized in Class V LN. Proteinuria is a very poor biomarker of immunological act...
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RE: Access to dialysis morbid obese non mobile 2 days ago
"The odds that PD will be successful is low" I would argue that HD access and home HD training success is similarly low I find you just cannot ...
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RE: Access to dialysis morbid obese non mobile 3 days ago
Thanks a lot We facing such challenges frequently and to preserve residual renal function we should start with PD until training or did PET if s...
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RE: NSAIDS and CKD 3 days ago
NSAIDs hurt or help Here are my personal observations and biases: Yes, I have seen tangible number of office patients NSAIDs appear to pr...
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RE: Access to dialysis morbid obese non mobile 3 days ago
Since I do not know what is the wt and height, I am making a guess. The odds that PD will be successful is low. This is a tough situation and we fa...
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