Kidney Health Initiative (KHI)

KHI Current Project

Development of a Roadmap for Innovations in Renal Replacement Therapy (RRT)

Technology Roadmap for Innovative Approaches to Renal Replacement Therapy

Read the Roadmap Fact Sheet Press Release Workgroup Members

During ASN Kidney Week 2018, Joseph V. Bonventre, MD, PhD announced the release of the "Technology Roadmap for Innovative Approaches to Renal Replacement Therapy". Dr. Bonventre led a multidisciplinary team during the two year process of developing the roadmap. The roadmap is intended to increase interest, investment, and innovation in renal replacement therapy. It is now available for innovators, researchers, and entrepreneurs.

Thanks to everyone who participated in the draft version comment period from August 15 to September 14. KHI appreciates all stakeholders who read and commented on the document.

A signature initiative for KHI, this technology roadmap outlines strategies and research pathways needed to more effectively and efficiently develop commercially viable RRT alternatives to current dialysis treatment. Initially developed by a diverse group of stakeholders from across the kidney community, the roadmap is distinguished by these key elements:

  • A patient-centered focus, with a clearly delineated, patient-developed vision of improved patient quality of life
  • Increased opportunities for multidisciplinary collaboration
  • Multiple solution pathways with various time horizons
  • Common design requirements to ensure that all solutions meet the same minimum technical expectations

This community-consensus approach will enable the research focus areas and priorities outlined in the roadmap to more effectively:

  • Foster the creativity and multidisciplinary innovation needed to spur advances in RRT
  • Help funding agencies and proposal reviewers assess the relevance and potential impacts of RRT project proposals
  • Encourage new interest and investment in the RRT field
  • Offer increased treatment options and an improved quality of life to ESRD patients

In the News

Project Background

In June 2016, the White House Organ Summit called for an increase in breakthrough research and development to improve outcomes for patients needing transplants. In response, KHI leadership established an initiative on Developing a Roadmap for Innovative Approaches to Renal Replacement Therapy (RRT) to foster a new, multidisciplinary approach to advancing solutions that can improve the lives of millions of kidney patients with end stage renal disease (ESRD). Learn more by reading the roadmap.

KidneyX

The roadmap offers innovators and entrepreneurs the common design requirements and development details needed to propel projects toward funding opportunities through KidneyX's Redesign Dialysis prize competition. The research priorities in the roadmap offer a strategic development and implementation pathway to support KidneyX's emphasis on expediting the development of new therapies.

KidneyX: Redesign Dialysis