ASN represents more than 21,000 kidney health professionals working to help people with kidney diseases and their families. Comprised of all of ASN's focus areas, the ASN Alliance for Kidney Health allows the society to continue its growth and work towards the goal of a world without kidney diseases.
The latest Nephrology Self-Assessment Program (nephSAP) issue, Volume 23: Issue 1 (May 2024): Pediatric Kidney Disease is now available online.
RE: KDIGO 2024 CLINICAL PRACTICE GUIDELINE FOR THE MANAGEMENT OF AAV 14 minutes ago
For anti-GBM disease (Goodpasture's Syndrome) the studies are mainly observational as well mentioned by Dr Glassock. The following is the summary...
View Discussion
RE: Primary FSGS 17 minutes ago
Rituximab is a good option given her noncompliance. Hopefully, you can give 2 initial 1 gram doses now and she will show up at least if and when ne...
View Discussion
Primary FSGS 30 minutes ago
20 ys old female was diagnosed as minimal change at 10 years old Non compliance Remission and relapses till 19 years Presented with Anasarca 7 mo...
View Discussion
IV Calcium for Hypocalcemia in Hemodialysis patients 37 minutes ago
Hi everyone, I have a small cohort of Hemodialysis pts with chronic hypocalcemia with mean 1.85 (normal 2.1-2.6 mmolL). Some were following parat...
View Discussion
RE: hyperaldosteronism without symptoms 46 minutes ago
Thank you, Dr. Glassock for posting this article demonstrating elevated aldosterone levels post colectomy. ------------------------------ Manooc...
View Discussion
RE: hypocomplementenemic urticarial vasulitis syndrome 6 hours ago
forgot to tell you that the patient had persistent low c3, negative anca, DNA, and ana ------------------------------ Abdulrahman Buali MD hamad ...
View Discussion
RE: hypocomplementenemic urticarial vasulitis syndrome 7 hours ago
thanks, dr richard ------------------------------ Abdulrahman Buali MD hamad town ------------------------------
View Discussion
RE: hypocomplementenemic urticarial vasulitis syndrome 8 hours ago
thank you for the feedback this patient was diagnosed at a government hospital with a history, of skin biopsy, and renal biopsy twice,hei on dial...
View Discussion
RE: hyperaldosteronism without symptoms 17 hours ago
I did find a single paper showing a striking elevation of plasma aldosterone following total colectomy in the rat. So far as I know this has never ...
View Discussion
RE: hyperaldosteronism without symptoms 21 hours ago
Yes, undetectable 24 urine sodium. He drinks copious water and restricts sodium in diet. ------------------------------ Nasimeh Yazdani MD Seasi...
View Discussion
RE: hypocomplementenemic urticarial vasulitis syndrome 1 day ago
Only one case report of recurrence of HUVS after kidney transplantation has been published. Due to publication bias, we do not have any idea what t...
View Discussion
RE: KDIGO 2024 CLINICAL PRACTICE GUIDELINE FOR THE MANAGEMENT OF AAV 1 day ago
No well powered RCT data in this subgroup of anti-GBM disease (with or without concomitant ANCA) exists but large observational studies , from many...
View Discussion
RE: KDIGO 2024 CLINICAL PRACTICE GUIDELINE FOR THE MANAGEMENT OF AAV 1 day ago
The American Society For Apheresis (ASFA) Guidelines in their 2019 version (before PEXIVAS) recommended: PLEX is accepted as "first-line therapy" (...
View Discussion
RE: KDIGO 2024 CLINICAL PRACTICE GUIDELINE FOR THE MANAGEMENT OF AAV 1 day ago
The Study PEXIVAS is the largest randomized trial for ANCA associated vasculitis and has many positive points. However, it has several key limitati...
View Discussion
RE: KDIGO 2024 CLINICAL PRACTICE GUIDELINE FOR THE MANAGEMENT OF AAV 1 day ago
Very informative discussion about ANCA vasculitis and DAH and data on PLEX. Do we have data supporting use of PLEX in AntiGBM Ab disease or good pa...
View Discussion
RE: hypocomplementenemic urticarial vasulitis syndrome 1 day ago
Interesting How was the diagnosis made? Was the cause of ESRD HUVS? How is this not lupus? We need more details Thanks ----------...
View Discussion
hypocomplementenemic urticarial vasulitis syndrome 1 day ago
dear colleagues, I would be obliged if I could have your opinions on a patient who was diagnosed with hypocomplementemia urticarial vasculitis sy...
View Discussion
RE: KDIGO 2024 CLINICAL PRACTICE GUIDELINE FOR THE MANAGEMENT OF AAV 1 day ago
It is of interest that the ACR/VF guidelines (2021) do not recommend PLEX for ANCA Vasculitis with a serum creatinine > 5.7mg/dL ----------------...
View Discussion
RE: KDIGO 2024 CLINICAL PRACTICE GUIDELINE FOR THE MANAGEMENT OF AAV 1 day ago
The guidelines based their recommendation on the results of a meta-analysis on the effect of PLEX in AAV - . Walsh M, Collister D, Zeng L, et al. T...
View Discussion
RE: KDIGO 2024 CLINICAL PRACTICE GUIDELINE FOR THE MANAGEMENT OF AAV 1 day ago
The largest single center observational examination of the efficacy of PLEX in DAH due to ANCA Vasculitis failed to show any benefits. (See Cartin-...
View Discussion
RE: KDIGO 2024 CLINICAL PRACTICE GUIDELINE FOR THE MANAGEMENT OF AAV 1 day ago
Where is the trial data that supports efficacy of PLEX compared to standard steroid and IS combinations in diffuse alveolar hemorrhage (DAH) in ANC...
View Discussion
RE: KDIGO 2024 CLINICAL PRACTICE GUIDELINE FOR THE MANAGEMENT OF AAV 1 day ago
I am attaching the email I received after listening to David Jayne's recent ANCA-KDIGO's presentation. I thoroughly enjoyed it and strongly encoura...
View Discussion
RE: KDIGO 2024 CLINICAL PRACTICE GUIDELINE FOR THE MANAGEMENT OF AAV 2 days ago
I think "consider" is the operative word here. If I had a patient with AAV and pulmonary hemorrhage I would use plex. I feel the risk of exclu...
View Discussion
RE: KDIGO 2024 CLINICAL PRACTICE GUIDELINE FOR THE MANAGEMENT OF AAV 3 days ago
Dr. Mahmoud- common confusion.Practice Points are Not evidence based recommendations. They are opinion based statements and opinions vary on this p...
View Discussion
RE: IgA Nephritis and pneumonia, underlying CKD with co morbidities 3 days ago
Thank you for this nice case Skin biopsy can show Ig Av or just leukoerythroblastic vascilitis --------------------------------- Mohamed Mahmoud...
View Discussion
RE: Membranous Nephropathy With Fouriner Gangrene 3 days ago
Sahin H, Aflay U, Kilinç N, Bircan MK. Coagulation parameters in the patients with Fournier's Gangrene. Int Urol Nephrol. 2005;37(4):733-7. doi: 10...
View Discussion
RE: Membranous Nephropathy With Fouriner Gangrene 3 days ago
Can we consider Fournier gangrene thrombotic event ? What’s Is IS protocol suggested ? --------------------------------- Mohamed Mahmoud MBBS ...
View Discussion
RE: Lupus podocytopathy 3 days ago
Studies from post-transplant recurrence of Nephrotic Syndrome of Finnish type suggest that autoantibodies can inujur podocytes in ways other than I...
View Discussion
KDIGO 2024 CLINICAL PRACTICE GUIDELINE FOR THE MANAGEMENT OF AAV 3 days ago
From KDIGO 2024 Practice Point 9.3.1.9: Consider plasma exchange for patients with SCr >3.4 mg/dl (>300 mmol/l), patients requiring dialysis or wi...
View Discussion
Kidney Translation Podcasts 3 days ago
Under the leadership of Dr. Matthew Sparks, Communications Editor, Portfolio Lead, the ASN journals have just released our first joint podca...
View Discussion
RE: Lupus podocytopathy 3 days ago
Dr.Mohammed. Thanks for this citation of a non-peer reviewed opinion paper. Unfortunately it was published before the finding of anti-nephrin antib...
View Discussion
RE: Lupus podocytopathy Friday, May 17 @ 11:47 AM
Thank you, Dr. Glassock for your explanation, the evidence is limited for case series and I would agree about the heterogenicity of the pathogenic ...
View Discussion
RE: case of hypercalcemia Friday, May 17 @ 9:59 AM
I think this person deserves a lymph node biopsy. I see that a bone marrow has been done but not a lymph node. Biopsy' of the node will give us the...
View Discussion
ATGam As An Induction In Kidney Tx Friday, May 17 @ 4:51 AM
Any one has experience with using ATGam (equine, pfizer) as an induction agent for kidney transplant recipient? If you use it , at which dose ? 5 ...
View Discussion
RE: gross hematuria Friday, May 17 @ 1:53 AM
I would compare albumin/creatinine ratio to the protein/creatinine ratio and if this is high, then the proteinuria is of glomerular origin and not ...
View Discussion
RE: Membranous Nephropathy With Fouriner Gangrene Thursday, May 16 @ 3:56 PM
Unless serum PLA2R Ab is very high and as UPCR is 4 g/g, this represent low risk of progression and no need to rush for IS therapy. Agree with othe...
View Discussion
case of hypercalcemia Thursday, May 16 @ 3:31 PM
49 yrs old gentleman was found to have hypercalcemia in the range of 11-14, chronic since a while. PTH suppressed in the 3 range Vit D 25 hydro...
View Discussion
RE: Membranous Nephropathy With Fouriner Gangrene Thursday, May 16 @ 11:13 AM
Yes not on SGLT2 inh Odema improving with diuretics Infection improving --------------------------------- Mohamed Mahmoud MBBS NEPHROLOGIST MOH ...
View Discussion
Research Idea for Nephrology Fellow ( Limited Fund ) and can be applied in limited health facilities Thursday, May 16 @ 9:57 AM
Hello folks I'm Darryl a nephrology fellow from Indonesia. Currently I will make my final thesis and looking for some idea for the research. C...
View Discussion
RE: IgA nephropathy with FSGS and mesangial proliferation also mild diabetic nephropathy - treatment recommendation Thursday, May 16 @ 9:32 AM
What is rambles 3 mg? Also something happened to the biopsy report when it was pasted here as some of it is incomprehensible. I don't understand wh...
View Discussion
RE: Membranous Nephropathy With Fouriner Gangrene Thursday, May 16 @ 8:52 AM
I assume not on sglt2 inhibitor? Diursese aggressively I believe edema is a risk factor for infection. Use loop thiazide and MRA if needed. ----...
View Discussion
RE: Membranous Nephropathy With Fouriner Gangrene Thursday, May 16 @ 2:24 AM
Fourniers gangrene is a Urosurgical Emergency. If he has not been taken for debridement and crp is 2, it's probably not Fournier. Resolution of oed...
View Discussion
RE: Membranous Nephropathy With Fouriner Gangrene Thursday, May 16 @ 1:50 AM
syphilis Serollogy negative Anti PL2 send Secondary work up going --------------------------------- Mohamed Mahmoud MBBS NEPHROLOGIST MOH Egyp...
View Discussion
RE: refractory temporal arteritis ( GCA) vs steroid myopathy vs. Wednesday, May 15 @ 10:23 PM
Creat 1.2 now UPCR and UACR , routine UA all wnl. Agree , not " nephrology per se, but less than adequate local rheum help (and find the two locall...
View Discussion
RE: Membranous Nephropathy With Fouriner Gangrene Wednesday, May 15 @ 10:21 PM
Suspected. Fournier ulcer on back ground of recently diagnosed membranous with low albumin this is the trigger for the infection and also. May be r...
View Discussion
RE: refractory temporal arteritis ( GCA) vs steroid myopathy vs. Wednesday, May 15 @ 9:06 PM
nl BP Creat max 1.4 (what is it now)? Normal urinalysis I think this is a rheum case not a nephrology case. I do admire your interest and p...
View Discussion
RE: A regular hemodialysis in an ESRD patient with a serum HCO3- of 7 meq/l after missing dialysis for 2 weeks? Wednesday, May 15 @ 8:29 PM
This reminds me of one of the arguments against giving bicarb for metabolic acidosis, Bicarb crosses the blood brain barrier slowly, but as you ...
View Discussion
RE: Artifical Intelligence Clinical Applications Wednesday, May 15 @ 6:31 PM
AI has a lot of potential improving CKD care. The applications so far that are more advanced range from prediction models for AKI incidence, CKD pr...
View Discussion
IgA nephropathy with FSGS and mesangial proliferation also mild diabetic nephropathy - treatment recommendation Wednesday, May 15 @ 5:30 PM
a 27-year-old male with persistent proteinuria, history of diabetes mellitus type 2 since last 5 years with urine protein creatinine ratio 1585 ...
View Discussion
IV Iron treatment in setting of remote h/o colon cancer Wednesday, May 15 @ 5:17 PM
A 87-year-old female patient with chronic kidney disease- recent creatinine 2.29 and GFR 20%. patient's hemoglobin is 7.6, percentage iron satur...
View Discussion