Intercalated Cells: Major Roles for a Minority Population

November 18, 2016 | 02:00 PM - 04:00 PM

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Basic/Clinical Science Session

Intercalated Cells: Major Roles for a Minority Population

November 18, 2016 | 02:00 PM - 04:00 PM

Location: W175

Session Description

The primary function of intercalated cells, the minority cell population in distal segments of the nephron, had long been considered to regulate acid-base homeostasis. Emerging evidence now suggests that these cells also participate in sodium, potassium, and ammonia transport and play a role in the innate immune system. This session provides an update on the ever-expanding roles of this minority cell population in homeostasis.

Honorary Moderator: Thomas D. DuBose, Jr., MD, FASN

Session Objectives

Upon completion of this session, the participant will be able to: 1. describe the role of intercalated cells in regulating electrolyte and acid-base homeostasis; 2. recognize acid-base sensors in intercalated cells; and 3. discuss the role of the intercalated cell in the response to infection.

Session Acknowledgements

In celebration of its 50th anniversary, ASN thanks former ASN Councilors Thomas D. DuBose, Jr., MD, FASN, and William B. Schwartz, MD.

Learning Pathway

  • Cell and Transport Physiology

Moderators

  • Qais Al-Awqati, MBChB
  • Fiona E. Karet, MD, PhD

Lectures

Acid-Base Sensing by Intercalated Cells Add to your Outlook, Google, Yahoo, or Apple iCal Calendar
02:00 PM - 02:30 PM
Nuria M. Pastor-Soler, MD, PhD, FASN

Role of Intercalated Cells in Electrolyte Homeostasis and Blood Pressure Regulation Add to your Outlook, Google, Yahoo, or Apple iCal Calendar
02:30 PM - 03:00 PM
Carsten A. Wagner, MD

Adaptation of Intercalated Cells to Acidosis: Role of Novel Paracrine Factors Add to your Outlook, Google, Yahoo, or Apple iCal Calendar
03:00 PM - 03:30 PM
George J. Schwartz, MD, FASN

Intercalated Cells in the Defense against Bacterial Pathogens Add to your Outlook, Google, Yahoo, or Apple iCal Calendar
03:30 PM - 04:00 PM
Jonathan M. Barasch, MD, PhD