RE: Case Of Progressive ckd / HTN 1 hour ago

WHAT IS THE PATIENTS HEIGHT BECAUSE THE LINGITUDANAL HEIGHT IS PROPRTIONAL TO THE PATIENT .BEFORE US, WE ESTMATED THE NORMAL HEIGHTFROM GLAT PLATES...

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RE: Case Of Progressive ckd / HTN 2 hours ago

Thanks Kidney size r 11 cm and l 10 cm ish So not small but agree biopsy will be chronic changes But patient wish ----------------------------...

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RE: rituxan and Obinutuzumab 4 hours ago

"I am treating a relapsed MGN patient with Rituxan" Does this mean proteinuria had resolved completely previously and now has reappeared? What is...

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RE: to pulse or not to pulse?? 4 hours ago

Both are true . ------------------------------ Richard Glassock MD, FASN Laguna Woods CA (949) 388-8885 ------------------------------

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RE: rituxan and Obinutuzumab 4 hours ago

Why are you treating a patient with a negative anti-PLA2R antibody in the circulation but with a positive PLA2R in the tissue . Is this a complete ...

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RE: rituxan and Obinutuzumab 6 hours ago

His serum APLA2Rab has always been negative, though it was positive in the biopsy X 2 and we even got his old biopsy tissue from 15 years ago that ...

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RE: to pulse or not to pulse?? 6 hours ago

Dr Glassock Is the increased uptake in pulmonary hemorrhage due to the release of Hb and CO can displace CO2 rom Hb. Whereas in CHF the CO uptake...

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RE: rituxan and Obinutuzumab 6 hours ago

We used Methylprednisolone 100 mg. When he reacted we gave him another 200 mg whcih quelled the reaction. But I am nervous to risk it. Thanks ---...

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RE: Case Of Progressive ckd / HTN 8 hours ago

Echogenicity usually means fibrosis in smallish kidneys. That why I did not favor a Bx. Risk/ benefit ratio too high ----------------------...

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RE: Case Of Progressive ckd / HTN 10 hours ago

Thanks everyone Urine dipstick done not microscopy Us kidneys both kidney appear echogenic Best wishes --------------------------------- Muh...

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RE: to pulse or not to pulse?? 10 hours ago

Dear all, Thanks Colleagues have told me that plex was not for PH but rather due to severity of disease as causing lung/ gi/ neurology / renal / p...

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RE: to pulse or not to pulse?? 14 hours ago

Agree with Dr. Glassock that PLEX is not indicted in this case and agree for CYC based induction therapy. Other non invasive new tool for differen...

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RE: PLA2R positive membranous nephropathy 17 hours ago

I wouldn't worry a lot about TB reactivation with 2 g of rituximab if the patient is on concomitant latent TB therapy. The risk would be higher if ...

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PLA2R positive membranous nephropathy 18 hours ago

Greetings to all community members seeking for inputs about this case 40 year old male patient diagnosed with membranous nephropathy since 2015...

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RE: to pulse or not to pulse?? 1 day ago

Check with your Pulmonary physician. The test is also called "Pulmonary Diffusion Capacity " or the "Krough" test. If the patient is receiving ster...

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RE: to pulse or not to pulse?? 1 day ago

Mpo>8 ( lab does not give a specific value) new hospital for me not encountered this before --------------------------------- Muhammad Soobadar M...

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RE: to pulse or not to pulse?? 1 day ago

Thanks prof glassock I don’t think I will do a repeat kidney biopsy . I will just treat as multi system vasculitis . It won’t change management a...

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RE: to pulse or not to pulse?? 1 day ago

Please do a single breath pulmonary CO uptake, this will differentiate between CHF , pneumonia and alveolar hemorrhage. The CO uptake is very high ...

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RE: Case Of Tunnelled Line Bactaeremia With Osteomyelitis And Endocarditid 1 day ago

Thanks both Patient already on taurolock when developed mssa bactaeremia. Think heading to vancomycin Lock Once permanent catheter inserted Lo...

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RE: to pulse or not to pulse?? 1 day ago

Just to Update - Friday evening after renal biopsy patient dropped saturation. Oxygen requirement of 2 l. Cxr - bilateral infiltrate . Hb stable ...

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RE: Case Of Progressive ckd / HTN 1 day ago

Let us know what the kidney biopsy shows when it is performed. ------------------------------ Richard Glassock MD, FASN Laguna Woods CA (949) 388...

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RE: Jim Kaufman obituary 1 day ago

I too am saddened by the news, Jim Kaufman and I interacted in both the anemia of CKD and the issue of thrombosis of VB fistulas, particularly thos...

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Encourage Your Fellows to Participate in the 2025 FIT Bowl at ASN Kidney Week 1 day ago

Encourage your fellows to join the American Society of Nephrology (ASN) Fellows-in-Training (FIT) Bowl at Kidney Week 2025 in Houston, TX. This yea...

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Apply to Participate in the 2025 FIT Bowl at ASN Kidney Week by Friday, September 5 1 day ago

Test your knowledge against your peers! Win ultimate bragging rights at Kidney Week! Join the American Society of Nephrology (ASN) Fellows-in-...

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RE: Case Of Progressive ckd / HTN 1 day ago

Following the discussion, I ask the following. Is he a sip;e SC trat ot Sickle cell + another genetic abnormality. i had 3 patients who had Hemoglo...

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RE: Case Of Progressive ckd / HTN 1 day ago

With progression of CKD over 5 years (or more) my guess us that a biopsy will showESKD and will be rather unhelpful in treatment decision , but it ...

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RE: Blood flow to dialysate flow ratio for full saturation 1 day ago

Dr Aledan, typically in CRRT, blood flow does not affect clearance at all, if I am correct. If the blood flow is >2.5 times the dialysate flow, whi...

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RE: Case Of Progressive ckd / HTN 1 day ago

Genetic test for APOL 1 variant is not available in UK. This test is available through National genomic only for potential living kidney donors of ...

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RE: Case Of Progressive ckd / HTN 1 day ago

I would be cautious upon making a diagnosis of cardiac amyloid from echocardiogram. The findings are not specific in the presence of CKD as I have ...

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RE: Case Of Progressive ckd / HTN 1 day ago

Amyloidosis of any type can explain preserved kidney size despite progressive CKD/ESKD. However, active urine sediment with hematuria is unlikely i...

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RE: Case Of Progressive ckd / HTN 1 day ago

Was hematuria confirmed by urine microscopy? I think patients with sickle cell trait, albeit less frequently l than those with sickle cell disease,...

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RE: rituxan and Obinutuzumab 1 day ago

Previously we use hydrocortisone for premedication and we observed many allergic reactions so we switch to methylprednisolone or dexamethasone so t...

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RE: Case Of Progressive ckd / HTN 1 day ago

I suppose that this might be hereditary ATTR Amyloidosis which is mire common in patients of West African ancestry and can be associated with Hyper...

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RE: Case Of Progressive ckd / HTN 1 day ago

Severe hypertension is very uncommon in renal amyloidisis, but it has been seen. ------------------------------ Richard Glassock MD, FASN Laguna ...

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RE: Case Of Progressive ckd / HTN 1 day ago

Can patient with amyloidosis suffer from severe hypertension?? --------------------------------- Alaa Nabih Abdalla nephrology fellow Egypt -----...

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RE: Case Of Progressive ckd / HTN 1 day ago

With an eGFR of 6ml/Min an ARR will have no value. I donut think I would do a MRA in this case. ------------------------------ Richard Glassock ...

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RE: Case Of Progressive ckd / HTN 1 day ago

Thanks why cardiologist suspected amyloidosis any suspicion by echo Aldosterone renin ratio?? As Dr Richard said renal doppler is safe more than ...

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RE: Case Of Progressive ckd / HTN 1 day ago

"Baseline eGFR 2020 50 ml/min 2024. 24 ml/min January 2025 15 ml/min" Above course suggests progressive CKD --> ESKD now, even though size of kid...

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RE: Case Of Progressive ckd / HTN 1 day ago

No kidney biopsy is needed before genetic testing for APOL1 high risk alleles. If positive for two risk alleles I think that a kidney biopsy and an...

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RE: rituxan and Obinutuzumab 1 day ago

I would not give another dose of RTX and try to get approval for OBI or Ofatumumab .What is his Anti-PLA2R-level.. if decreasing from pre-therapy y...

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RE: rituxan and Obinutuzumab 1 day ago

Thanks for those references, Dr Rodby. ------------------------------ Michael Klein M.D. New York Medical College Valhalla, NY (914) 493-7701 ---...

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RE: rituxan and Obinutuzumab 1 day ago

Thanks for your response, Dr Glassock It was a reaction with hives, shortness of breath, and tachycardia. It resolved with additional steroid and...

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RE: Case Of Progressive ckd / HTN 2 days ago

Could not hear Bruits Bw --------------------------------- Muhammad Soobadar MBChB UK ---------------------------------

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RE: Case Of Progressive ckd / HTN 2 days ago

Thanks prof glassock . Will ask radiologist if they can do us Doppler Would I not need kidney biopsy first before genetic test ? ---------------...

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RE: Case Of Progressive ckd / HTN 2 days ago

Have you performed an APOLI genetic analysis . This might be APOL-mediated kidney disease (AMKD.) Are any bruits present in abdomen. I suppose with...

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Jim Kaufman obituary 2 days ago

Dear colleagues, Attached is an obit for my friend and mentor Jim Kaufman. Jim spent most of his career at Boston University and the Boston VA. T...

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Case Of Progressive ckd / HTN 2 days ago

Dear colleagues , I would appreciate input 50 male patient family roots from Western Africa but born in UK. PMH- Sicke cell trait , severe HTN qu...

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RE: rituxan and Obinutuzumab 2 days ago

My apology for this simple question, which steroids are used for premeditation? --------------------------------- Hayder Aledan MD, FASN Professor...

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RE: rituxan and Obinutuzumab 2 days ago

I had a harder time getting Ofatumumab than Obi, for whatever that is worth see attached ------------------------------ Roger Rod...

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RE: Blood flow to dialysate flow ratio for full saturation 2 days ago

For example,Handbook of Dialysis by Dugirdas could be a reference for that. ------------------------------ Ahmed Yasin, MD,FASN Al Ahmady,Hospita...

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