Feeling the Pinch of Salt: Intrarenal Renin-Angiotensin System and Hypertension

November 18, 2016 | 02:00 PM - 04:00 PM

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Basic/Clinical Science Session

Feeling the Pinch of Salt: Intrarenal Renin-Angiotensin System and Hypertension

November 18, 2016 | 02:00 PM - 04:00 PM

Location: S105

Session Description

As new discoveries reveal the complexity of the renin-angiotensin system (RAS), the central role of the RAS in the kidney in BP regulation becomes even more apparent. The intrarenal RAS is regulated completely separately from circulating RAS components. The session details how the RAS functions locally within the kidney to modulate BP in health and disease.

Session Objectives

Upon completion of this session, the participant will be able to: 1. explain how angiotensin triggers further activation of the intrarenal RAS; 2. describe the mechanisms through which intrarenal ACE and angiotensin II modulate BP through effects on renal sodium transport; and 3. define the cross-talk between the intrarenal dopaminergic and RAS systems.

Session Acknowledgements

In celebration of its 50th anniversary, ASN thanks former ASN Councilors Thomas E. Andreoli, MD, and Thomas M. Coffman, MD, FASN.

Learning Pathways

  • Hypertension and Cardiovascular Disease
  • Cell and Transport Physiology

Moderators

  • Thu H. Le, MD
  • Tianxin Yang, PhD

Lectures

Role of Collecting Duct Renin in the Pathogenesis of Hypertension Add to your Outlook, Google, Yahoo, or Apple iCal Calendar
02:00 PM - 02:30 PM
Minolfa C. Prieto, MD, PhD

Key Interactions between the Dopaminergic and Renin-Angiotensin Systems in Hypertension Add to your Outlook, Google, Yahoo, or Apple iCal Calendar
02:30 PM - 03:00 PM
Pedro A. Jose, MD, PhD

Blood Pressure Regulation by the Type 1 Angiotensin Receptor in the Proximal Tubule Add to your Outlook, Google, Yahoo, or Apple iCal Calendar
03:00 PM - 03:30 PM
Susan B. Gurley, MD, PhD

Intrarenal ACE as a Catalyst for Hypertension Add to your Outlook, Google, Yahoo, or Apple iCal Calendar
03:30 PM - 04:00 PM
Romer Andres Gonzalez-Villalobos, MD, PhD