nephSAP: Volume 8
Volume 8, Number 1, January 2009
Pediatric Nephrology
Howard Trachtman, MD and Debbie Gipson, MD
AMA PRA Category 1 Credits™
In the broad-ranging review by Trachtman and Gipson (1), it must be apparent that the clinical care of children with kidney disease has advanced significantly in the past 25 to 30 yr. Remarkable advances such as dialysis and transplantation for infants an...
Volume 8, Number 2, March 2009
Fluid, Electrolyte, and Acid-Base Disturbances
Biff F. Palmer, MD and Richard H. Sterns, MD
AMA PRA Category 1 Credits™
In the past several years, new information has emerged on the complex regulatory network that governs renal control of electrolyte and water balance. In addition to the molecular and atomic specificity of various channel proteins, signaling pathways have ...
Volume 8, Number 3, May 2009
Acute Kidney Disease and Critical Care Nephrology
Paul M. Palevsky, MD and Patrick T. Murray, MD
AMA PRA Category 1 Credits™
Despite substantial advances in techniques of resuscitation and renal replacement therapy, mortality in the critically ill population with acute kidney injury (AKI) remains alarmingly high. Overall mortality has been reported to be 40 to 60% in critically...
Volume 8, Number 4, July 2009
Chronic Kidney Disease and Progression
Jeffrey S. Berns, MD and Steven Fishbane, MD
AMA PRA Category 1 Credits™
Until the close of the 20th century, chronic kidney disease (CKD) was referred to by many different names yet attracted little interest until uremic symptoms demanded the initiation of dialysis. In the past decade, greater awareness of this disorder has d...
Volume 8, Number 5, September 2009
Interventional Nephrology
Arif Asif, MD and Anil Agarwal, MD
AMA PRA Category 1 Credits™
Optimizing vascular access outcomes continues to pose a major challenge to practicing nephrologists (1). Fistulas are the best long-term type of vascular access, but their high primary failure (nonmaturation) rate is an obstacle to increasing their preval...
Volume 8, Number 6, November 2009
Transplantation
John P. Vella, MD and David J. Cohen, MD
AMA PRA Category 1 Credits™
The appropriate immunosuppression for renal transplantation is based on the concepts of prevention of rejection and prolongation of graft and patient survival while preventing infection, malignancy, adverse effects, and burdensome costs. Transplant physic...