ASN represents more than 21,000 kidney health professionals working to help people with kidney diseases and their families. Comprised of all of ASN's focus areas, the ASN Alliance for Kidney Health allows the society to continue its growth and work towards the goal of a world without kidney diseases.
The latest Nephrology Self-Assessment Program (nephSAP) issue, Volume 23: Issue 5 (Dec 2024): Transplantation is now available online.
RE: FSGS with mesangial IC "full house" 2 hours ago
The normal serum albumin and severe nephrotic range proteinuria makes Primary FSGS very unlikely. The IF and EM point toward C1q Nephropathy. With ...
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RE: FSGS with mesangial IC "full house" 3 hours ago
SAlb and lipids level? ANA, C3, C4, anti D.S.-DNA ab? Extent of edema? ------------------------------ K.K. Venkat MD Troy MI (248) 420 7798 -----...
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RE: IgA nephropathy case in a young Caucasian female 8 hours ago
60-70% IFTA ------------------------------ Janis Lawrence-Jackson DO, FASN Sarasota FL (941) 917-8722 ------------------------------
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RE: IgA nephropathy case in a young Caucasian female 8 hours ago
severe IFTA ------------------------------ Janis Lawrence-Jackson DO, FASN Sarasota FL (941) 917-8722 ------------------------------
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RE: IgA nephropathy case in a young Caucasian female 8 hours ago
cystatin C 1.77 ------------------------------ Janis Lawrence-Jackson DO, FASN Sarasota FL (941) 917-8722 ------------------------------
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RE: IgA nephropathy case in a young Caucasian female 8 hours ago
severe epithelial foot process effacement; tubular basement membranes are without deposits ------------------------------ Janis Lawrence-Jackson ...
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RE: Is It LN?? 10 hours ago
Prof glassock another question if I may Aki and nephrotic syndrome ( efgr 30 from 90 with urine pcr>10 g lets say and primary membranous do you use...
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FSGS with mesangial IC "full house" 12 hours ago
Would appreciate input regarding next steps in management. 52 yo M with obesity (BMI - 58), HTN on Lisinopril, gout was referred to our practice...
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RE: Is It LN?? 12 hours ago
Thanks prof glassock . Appreciate your input and helpful as always --------------------------------- Muhammad Soobadar MBChB UK ---------------...
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RE: Timings for stoping Mycophenolate after Rituximab 12 hours ago
If MMF therapy was failed and you want to initiate RTX, I will stop MMF abruptly and I see that RTX works faster in MCD compared to MN. ----------...
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RE: IgA nephropathy case in a young Caucasian female 13 hours ago
Any data that microscopic hematuria is a risk factor for CKD progression? Any thoughts about this slide from the ISN academy lecture about utility...
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RE: Primary Hyperparathyroidism 13 hours ago
I agree with prof Glassock and find sestamibi to be of limited value in this situation ------------------------------ Stuart Sprague DO, FASN Dir...
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RE: Proteinuria 13 hours ago
My thoughts were strive to not to discontinue SGLT2i in patients with recurrent UTI as treat them empirically with ABX and recurrent to use long-te...
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RE: IgA nephropathy case in a young Caucasian female 13 hours ago
Dr. Alhosaini. The 2021 KDIGO CPG for IgAN are very out of date and largely obsolete. New final revised CPG are expected to be released this summer...
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RE: IgA nephropathy case in a young Caucasian female 13 hours ago
What is the current level of hematuria? If minor, and with a prior biopsy showing a T2 lesion, I doubt that steroids (in any form ) will delay the ...
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RE: IgA nephropathy case in a young Caucasian female 14 hours ago
I look at this differently, She is headed for ESRD and I could not sit back and watch this without trying something. I'm not sure how to know wh...
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RE: IgA nephropathy case in a young Caucasian female 14 hours ago
While l agree with the Ckd lowering methods describe above as well as a tight BP control , given the level of proteinuria and relative low creatini...
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RE: IgA nephropathy case in a young Caucasian female 14 hours ago
Her serum creatinine may underestimate her eGFR so can you do eGFR Cr-cystatin-c? Because her serum creatinine doesn’t fit with severe IFTA on bio...
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RE: IgA nephropathy case in a young Caucasian female 15 hours ago
What signs of active inflammation are present at this time. Steroids are not useful in treating FSGS secondary to IgAN, unless a diffuse Podocytopa...
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RE: Refractory membranoproliferative glomerulonephritis 15 hours ago
Positive RF, MPGN pattern of injury and marked predilection for IgM deposition suggests old burnt out HCV infection with a monoclonal IgM Kapoa MGR...
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RE: Central diabetes insipidus with a nephrogenic component? 16 hours ago
Bright spot imaging by MRI has reported low sensitivity and specificity for Central DI in polyuria states. ------------------------------ Richar...
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RE: Primary Hyperparathyroidism 16 hours ago
In my limited experience, Sestamibi scan is of little utility in for guiding management in this situation. Any opinions Dr.s Venkat and Sprague.? ...
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RE: Central diabetes insipidus with a nephrogenic component? 16 hours ago
The MRI was shown suspension of high intensity (bright spot) on T1-weighted image, doesn’t this suggestive of central DI? New DDAVP test suggestiv...
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RE: Central diabetes insipidus with a nephrogenic component? 16 hours ago
Was the water deprivation just 3 hours or overnight plus 3 hours? Was a copeptin sent when the s Osm was 299 and U osm 115? If so, is it back yet...
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Proteinuria 17 hours ago
Hello all. I would appreciate your help with this case - 62YOF with long standing T2DM, HTN. In 5/2023 SCr was 1.2 with 10gram of albuminuria- R...
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RE: Primary Hyperparathyroidism 17 hours ago
Postransplant hypercalcemia is common and with excellent graft function, hypophosphatemia is also common which tend to perpetuate and intensify hyp...
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RE: Central diabetes insipidus with a nephrogenic component? 18 hours ago
With only 3 hours of water deprivation and no documented weight loss, the WDT is inconclusive , in my opinion. A copeptin test is the next step. ...
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RE: Central diabetes insipidus with a nephrogenic component? 21 hours ago
Yes, I ordered a chest CT scan and I'm waiting ------------------------------ Thaisa Valverde MD, MSc ARACAJU 557999911168 ----------------------...
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RE: Refractory membranoproliferative glomerulonephritis 1 day ago
Good morning, Many thanks for your responses, attached you will find the biopsy report translated from german. Antinuclear antibodies inclu...
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RE: Primary Hyperparathyroidism 1 day ago
This is a relatively small, but difficult group to address. I agree with Dr Venkat as to the pts who need treatment, but generally go with medical ...
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RE: IgA nephropathy case in a young Caucasian female 1 day ago
@Richard Glassock Dr. Glassock, my understanding is that the KDIGO guidelines on IgA nephropathy discourage making treatment decision based on biop...
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RE: Central diabetes insipidus with a nephrogenic component? 1 day ago
What were the hourly urine volumes during the water deprivation test, so that osmolal excretion can be assessed. I agree that a copeptin test after...
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RE: Primary Hyperparathyroidism 1 day ago
@Tunde Tijani Regarding management of hypercalcemic secondary HPT ("tertiary" HPT) post-transplant with preserved renal function, indications for m...
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RE: IgA nephropathy case in a young Caucasian female 1 day ago
The addition of a non- steroidal mineralocorticoid antagonist (MRA to the therapeutic regimen of such a patients with IgAN ( without diabetes) is n...
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RE: Primary Hyperparathyroidism 1 day ago
Are you referring to "tertiary hyperparathyroidism," post kidney transplant in oatientsxwho have developed autonomously functioning parathyroud gla...
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RE: Primary Hyperparathyroidism 1 day ago
@Tunde Tijani: I agree with you that adynamic bone disease can cause hypercalcemia with elevated PTH (though lower than its previous highs). Howeve...
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RE: IgA nephropathy case in a young Caucasian female 1 day ago
thank you for your reply ------------------------------ Janis Lawrence-Jackson DO, FASN Sarasota FL (941) 917-8722 ------------------------------
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RE: IgA nephropathy case in a young Caucasian female 1 day ago
thank you for your comments; uric acid was not done ------------------------------ Janis Lawrence-Jackson DO, FASN Sarasota FL (941) 917-8722 ---...
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RE: Central diabetes insipidus with a nephrogenic component? 1 day ago
Seems to fit (more clearly now) with CDI. Have you considered sarcoidosis to tie in with his stones/hypercalciuria? -----------------------------...
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RE: Is It LN?? 1 day ago
This is mist compatible with Primary Membranous Nephropathy , PLA2R positive subtype . The weak Ciq and IgM staining make LN and non Lupus Full Hou...
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RE: Is It LN?? 1 day ago
Is this case dual membranous nephropathy with non lupus full house gn? Or just membranous nephropathy ? Bw --------------------------------- Muham...
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RE: Is It LN?? 1 day ago
Conclusion: Native renal biopsy - Overall, the appearances are those of a membranous pattern of glomerulonephritis. There are mixed features seen a...
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RE: Is It LN?? 1 day ago
Previously biopsy-proven tip variant FSGS in 2013. Patient received oral steroids, responded. Prostate cancer June 2024 received radiotherapy. Past...
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RE: Is It LN?? 1 day ago
Thanks so much prof rodby --------------------------------- Muhammad Soobadar MBChB UK ---------------------------------
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RE: Central diabetes insipidus with a nephrogenic component? 1 day ago
The initial p Na of 143 is inconsistent with primary polydipsia (but remains possible). A persistently dilute urine with water deprivation sugges...
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RE: Primary Hyperparathyroidism 1 day ago
Excellent discussion, Dr Venkat.. Perhaps missing from this list is the hypercalcemia/high PTH combo of Adynamic Bone Phenomenon; the PTH may have...
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RE: Central diabetes insipidus with a nephrogenic component? 1 day ago
Updates: I admitted the patient for water deprivation testing. The initial serum osmolarity was 295, urinary osmolarity 165 and plasma sodium 143. ...
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RE: Is It LN?? 1 day ago
@Muhammad Soobadar "@ prof rodby eurolupus is 6 pulses of cyclophosphamide any steroids ?" see attached but: "Immediatel...
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RE: Frequent relapsing MCD 1 day ago
I dont see any reason to wait, you have proven the need for this, your patient seems steroid dependent based on the last 6 months. I would give the...
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RE: Diffuse proliferative Gn with IgG kappa deposits allograft failure 1 day ago
FU BM- Flow with no abnormal plasma cell population. Will order PET and see where it takes us. Thx again for the input. -------------------------...
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