RE: Fwd: NKF and ASN Recommend Race-Free Approach to Estimate GFR 3 hours ago

Agree The idea of homogeneous race biology is not appropriate so race adjustments are not what we want to have as patient facing data. Steve is rig...

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RE: Fwd: NKF and ASN Recommend Race-Free Approach to Estimate GFR 4 hours ago

The attempt to remove race in the various equations will be another motivator to get patients on dialysis too early since many peoples estimated gl...

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RE: Rasburicase preemptive admin? 4 hours ago

I would hold off.  Since the kidney function is already improving with the ureteral stent, there is no reason to correct the hyperuricemia rapidly....

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RE: Rasburicase preemptive admin? 4 hours ago

Are there 2 separate q’s here: 1. Would you give it for hyperuricemia from hemolysis-related AKI? No, no evidence & AKI improving. 2. Would you g...

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RE: Peritoneal dialysis in patients with Pre-existing PEG tube, for a football player in his early 20s 7 hours ago

The basketball/football player needs a pre-emptive Kidney transplant. What are the possibilities? --------------------------------- Richard Glasso...

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RE: Rasburicase preemptive admin? 9 hours ago

"AKI is resolving...  With decreasing SCr, serum uric acid level may be declining already and very expensive rasburicase may not be needed." I agr...

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RE: Peritoneal dialysis in patients with Pre-existing PEG tube, for a football player in his early 20s 9 hours ago

https://pubmed.ncbi.nlm.nih.gov/11510264/ "In PD patients, PEG feeding is associated with frequent complications. However, PEG placement prior to ...

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RE: Treatment of IgA Nephropathy 12 hours ago

The limitations of kidney biopsy and whole kidney GFR are that both, alone or combined in disease states, cannot give an accurate picture of the ra...

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RE: Fwd: NKF and ASN Recommend Race-Free Approach to Estimate GFR 15 hours ago

I agree the using cystatin c and creat gives better coordination with iothalamate clearance in looking at a population of people. my understanding ...

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RE: Treatment of IgA Nephropathy 15 hours ago

Dear Dr. Dastoor, What I find from your description and the graph is that She had two peaks of proteinuria, once at time of 1st presentation in 201...

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Peritoneal dialysis in patients with Pre-existing PEG tube, for a football player in his early 20s 17 hours ago

Hello,  I was looking into getting experience, studies and any information on the implementation of PD treatment for 2 different scenarios:  1. 8...

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RE: Fwd: NKF and ASN Recommend Race-Free Approach to Estimate GFR 21 hours ago

I agree with the comments made. In my opinion race should be replaced by ethnicity, which in and of itself is problematic. The AA race term used in...

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RE: Rasburicase preemptive admin? 1 day ago

This is a very interesting issue. Rasiburicase is indicated in “Tumor Lysis Syndrome” largely to prevent AKI due to Uric Acid crystallization in th...

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Speakers Bureau - Women Speakers 1 day ago

Women In Nephrology Speaker's Bureau Google Docs remove preview Women In Nephrology Speaker's Bureau Full Name Degree(s) Email addr...

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RE: Rasburicase preemptive admin? 1 day ago

AKI is resolving. What is the urine output trend and repeat serum uric acid level?  With decreasing SCr, serum uric acid level may be declining alr...

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Academic clock 1 day ago

In the Women In Nephrology leadership conference, a very interesting idea was brought forward.  In academic centers, the career clock ticks at a pa...

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RE: Rasburicase preemptive admin? 1 day ago

Cooking, going to take some time to come back I was told ------------------------------ Nimra Sarfaraz DO Dallas Renal Group (516) 637-3820 ------...

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RE: Treatment of IgA Nephropathy 1 day ago

Dr. Balan, as usual, has focused on the central issue raised by this case. How should findings on kidney biopsy (original or repeat) be used to mak...

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RE: Fwd: NKF and ASN Recommend Race-Free Approach to Estimate GFR 1 day ago

Because the serum creatinine Level is systematically increased in African-American Black subjects (but not African Black subjects) , compared to Wh...

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RE: Fwd: NKF and ASN Recommend Race-Free Approach to Estimate GFR 1 day ago

Can some body define race for me As I understand race is socially defined with no biological variance. There may be small genetic variance As i und...

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RE: Rituximab for maintenance in ANCA vasculitis 1 day ago

Thank you, Dr Glassock. ------------------------------ Tahsin Masud Emory University Atlanta, GA ------------------------------

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RE: Addressed to Dr Glassock Age and CKD 1 day ago

Dr. Balan- I am deeply grateful for your very generous comments. I have to watch out that my head does not swell to much with such praise. I want y...

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RE: Addressed to Dr Glassock Age and CKD 1 day ago

I would also like to add my own appreciation of Dr Glassock. I first learnt of him in 1996 when I started reading his book on Nephrology (Massry an...

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RE: Treatment of IgA Nephropathy 1 day ago

She has worsening renal function and biopsy showing S1 and T1 lesions. The proteinuria is not nephrotic range. Both the StopIGA and TESTING trials ...

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RE: Rasburicase preemptive admin? 1 day ago

What is the urine Uric acid to creatinine  ratio? ------------------------------ Richard Glassock MD, FASN Emeritus Professor David Geffen School ...

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RE: Fwd: NKF and ASN Recommend Race-Free Approach to Estimate GFR 1 day ago

This situation is actually not infrequent. I agree. ------------------------------ Neal Bhagwandass MBBS Internal Medicine/Nephrology San Fernando...

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Rasburicase preemptive admin? 1 day ago

Good morning! I have a complicated and interesting case that is still unfolding 59M w normal creat in 2005 presenting with abdominal fullness foun...

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RE: Addressed to Dr Glassock Age and CKD 1 day ago

My Most beloved and respected Professor Dr. Glassock I have been simply overjoyed since I received a thank you note especially from YOU  You are ...

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RE: Addressed to Dr Glassock Age and CKD 1 day ago

Undoubtedly Sir!  I have seen you practicing what you preach - treating learning and teaching as being just two sides of one coin.  It was opportu...

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RE: PLA2R Positive Membranous Nephropathy in elderly - To treat or not to treat 1 day ago

Dr. Vellanki, I still rely on a renal biopsy before embarking on immunosuppressive therapy in MGN. Many a time we do see a lot of chronicity in the...

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RE: PLA2R Positive Membranous Nephropathy in elderly - To treat or not to treat 1 day ago

Dr. Glassock, we do have facilities to test for NELL and THSD7A. We rely on PLA2R negativity, symptomatology and clinical examination to decide on ...

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RE: PLA2R Positive Membranous Nephropathy in elderly - To treat or not to treat 1 day ago

This is tough case and does not belong to the usual membranous nrphropathy cases we see in clinic. From a therapeutic stand point both anticoagulat...

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RE: PLA2R Positive Membranous Nephropathy in elderly - To treat or not to treat 1 day ago

The clinical association of hypothyroidism and membranous nephropathy (and other auto-immune glomerular diseases)  has been well described in the l...

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RE: PLA2R Positive Membranous Nephropathy in elderly - To treat or not to treat 1 day ago

Dr.Glassok, there are now recommendations to move towards combination therapy in membrsnous nephropathy with a Ritux, cytoxon and steroids to achie...

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RE: PLA2R Positive Membranous Nephropathy in elderly - To treat or not to treat 1 day ago

In the current PLA2R era, there are now enough publications to suggest not to biopsy should serum PLA2R upfront be positive,  would you then consid...

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RE: PLA2R Positive Membranous Nephropathy in elderly - To treat or not to treat 1 day ago

Surpridingly the hidden costs of monitoring a patient on alkylating therapies can well add up to a significant burden, in this 90 yrs  elderly pers...

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RE: PLA2R Positive Membranous Nephropathy in elderly - To treat or not to treat 1 day ago

Dear Dr. Goyal, He never had any symptoms to suggest malignancy. He was not a smoker or ethanolic. We did a few tests though. Fecal occult blood wa...

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Fwd: NKF and ASN Recommend Race-Free Approach to Estimate GFR 2 days ago

I worry that patient that are at the tails of the bell shaped curve are being misdiagnosed For example: 1) a 35 yo AA male has a creatinine of 1.5....

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RE: lupus mesangial class 2 with podocytopathy 2 days ago

What does “moderately effaced” mean?. In Lupus Podocytopathy there is usually diffuse foot process effacement (> 80% ). What method was used for me...

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lupus mesangial class 2 with podocytopathy 2 days ago

62-year-old African American male history of SLE, COPD (mild) previous  latent TB (remote) serum creatinine is 0.6 mg/dL. Serum albumin is 3.3 g/d...

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RE: Rituximab for maintenance in ANCA vasculitis 2 days ago

I would give 1000mg RTX and a short course of oral steroids. Check the CD19 and antiMPO in 3 months. Opinion only. No repeat kidney biopsy needed. ...

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RE: Rituximab for maintenance in ANCA vasculitis 2 days ago

I had a similar patient, 63 y/o f diagnosed MPO vasculitis in Jan 2018 with pulmonary symptoms, Cr 2.7, MPO 224, treated with rituximab 600 mg week...

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RE: membranous nephropathy 2 days ago

Hi Dr Jha, I greatly appreciate your input and thank you, as you said its always new twist and turns in management, will keep you posted depending ...

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Nephrology Quiz and Questionnaire KW21 2 days ago

Your help is needed.  We need you to take the Nephrology Quiz and Questionnaire and try to outsmart the Nephrology Program Directors and the Nephro...

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RE: C3gn ? 2 days ago

If the genetic analysis were to reveal a pathogenic mutation, would you pursue any treatment, like steroids or MMF?If you have already decided not ...

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RE: PLA2R Positive Membranous Nephropathy in elderly - To treat or not to treat 2 days ago

I  am sorry to side track from the main issue. But i was struck with the recent diagnosis of hypothroidism in this elderly gentleman.  I have in my...

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RE: C3gn ? 2 days ago

I am not aware if he has any Greek ancestry I thought about genetic testing but I kind of have some hesitancy since he’s 80 years old and has moder...

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RE: C3gn ? 2 days ago

Does the patient happen to be of Greek-Cypriot ancestry? A mutation in CFHR5 needs to be considered as it is a cause of “C3GN” appearing in older s...

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RE: C3gn ? 2 days ago

Scr 2,5 stable Since Last yr No M spike Upep not done Complement levels notmal Kappa 72, lambda 38. Ratio 1.8 Thnx for the input ----------------...

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RE: Addressed to Dr Glassock Age and CKD 2 days ago

Dr. Reen— many thanks for your kind words and also for your many excellent contributions to the ASN Communities. Much appreciated. ---------------...

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