ASN represents more than 21,000 kidney health professionals working to help people with kidney diseases and their families. Created with input from all of ASN's constituencies, the new ASN logo allows the society to continue our growth and work toward a goal of a world without kidney diseases.
The latest Nephrology Self-Assessment Program (nephSAP) issue, Volume 21: Issue 1 (Apr 2022): Acute Kidney Injury and Critical Care Nephrology is now available online.
RE: Primary or Secondary MN 1 hour ago
This case illustrates very well why the terms Primary and Secondary as categories of MN are quickly losing relevancy as the diversity of antigen sy...
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RE: Lupus nephritis 2 hours ago
might be acquired Nephrogenic Syndrome of inappropriate anti-diuresis due to IV CYC, but COVID might be a factor too. I might try oral urea. You ma...
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RE: Lupus nephritis 4 hours ago
Issues and questions with my 25 yo Asian lupus patient initially posted 4/22/2022 As suggested and after repeat renal biopsy now noting class 4 a...
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RE: Primary or Secondary MN 7 hours ago
"Thus, NELL1-associated membranous nephropathy has a unique histopathology characterized by incomplete capillary loop staining, IgG1-predominance, ...
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RE: Secondary cause for this TTP? 9 hours ago
No he didn't. ------------------------------ Naji Alhamid. Nephrologist Almawasat University Hospital. Damascus, Syria. [+951603382] ------------...
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RE: Hypercalcemia and PTHrP 10 hours ago
Hi Muhammad, You might enjoy the Renal Fellow Network series called The Skeleton Key Group. This resource is vetted by and reviewed my myself and ...
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RE: Hypercalcemia and PTHrP 10 hours ago
Sorry- I can’t meet your requests. Maybe Dr. Rodby or Sprague can help. Have you searched Google Scholar or PubMed (Reviews)? . Also, UpToDate May...
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RE: Biopsy In Anti Gbm Disease 10 hours ago
Thank you all --------------------------------- Muhammad Soobadar MBChB UK ---------------------------------
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RE: Hypercalcemia and PTHrP 10 hours ago
Case base discussion Clinical vignette , lab parameters followed by question and discussion/answers Bw --------------------------------- Muhamma...
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RE: Biopsy In Anti Gbm Disease 11 hours ago
If his anti-GBM antibodies are negative now and his SCr stable, I would begin to taper the Steroids and CYC now and follow the AntiGBM levels. Cont...
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RE: Primary or Secondary MN 11 hours ago
Arkana Pathology labs in Little Rock AK performs this stain routinely . I think that as a first pass, age specific standard cancer Screeing may be...
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RE: Immunotactoid GN therapy (in a dog) 11 hours ago
Not too surprising since less than 10% of the CD38+ B Cells in dogs bone marrow are kappa LC positive . Kappa LC Monoclonal gammopathies must there...
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RE: Hypercalcemia and PTHrP 11 hours ago
Not sure I understand your request. Please clarify what kind of resources you are requesting. --------------------------------- Richard Glassock M...
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RE: Primary or Secondary MN 11 hours ago
Thank you Dr. Glassok, will investigate where to send for Amyloid P. My hospital doesn't do it. Contrast CT chest abdomen and pelvis not suggesti...
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RE: Primary or Secondary MN 11 hours ago
Looks likely NELl1 Work up malignancy needed Other work up as suggested --------------------------------- Bajinder Reen MD Brampton ON (905) 453...
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RE: Biopsy In Anti Gbm Disease 11 hours ago
"he never required dialysis creatinine stuck at 3.2." Given ~ 75% crescents and diagnosis of anti-GBM antibody RPGN, this patient has done remarkab...
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RE: Hypercalcemia and PTHrP 14 hours ago
Hi do you have resources about interpreting Calcium/phosphate pth in renal disease as cases ? Bw --------------------------------- Muhammad Soob...
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RE: Primary or Secondary MN 15 hours ago
The mesangial and sub-endothelial deposits suggest a secondary MN. With IgG1 predominance can you stain for NELL-1? Due to his age and PLA2R negati...
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RE: Immunotactoid GN therapy (in a dog) 15 hours ago
Bortezimib has actually been used in dogs- but to a very small extent for oncologic indications. I personally don't have any experience with it. Se...
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RE: Immunotactoid GN therapy (in a dog) 15 hours ago
We stained for kappa in all of our IF evaluations and after 7 years of never having a positive result in any dog with immune complex GN, therefore ...
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Primary or Secondary MN 16 hours ago
Hello, would like to hear your opinion, and suggestions for treatment. 57 YO man, previously healthy, developed LE edema rather quickly 3 months ...
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RE: ?Recurrent GN 17 hours ago
Yes it can, but you need the EM to fully evaluate this possibility. The diagnosing and treating the mass in the native kidney is a priority here. ...
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RE: ?Recurrent GN 17 hours ago
I wouldn't subject the patient to further immunosuppressive before clarifying the issue of RCC and you probably will need to change IS -----------...
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RE: ?Recurrent GN 18 hours ago
Thank You Dr Glassock, Dr Venkat and Dr Millat for your valuable comments. Can permeability factor FSGS recur in such insidious manner? Would Plex+...
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RE: Biopsy In Anti Gbm Disease 18 hours ago
I assume that the anti-GBM antibody levels have declined to low or undetectable levels, and that the patients has always been ANCA negative. In tha...
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RE: Secondary cause for this TTP? 19 hours ago
Curious….did he receive the COVID-19 shot? ------------------------------ Erin Greer MD MD Avera Nephrology Group Sioux Falls SD (850) 358-9895 --...
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RE: Biopsy In Anti Gbm Disease 19 hours ago
No infection --------------------------------- Muhammad Soobadar MBChB UK ---------------------------------
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RE: Biopsy In Anti Gbm Disease 19 hours ago
Thanks prof rodby If you have someone who is oligoanuric , Dialysis dependent anti gbm positive no pulmonary haemorrhage still remains dialysis dep...
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RE: Immunotactoid GN therapy (in a dog) 19 hours ago
Since this a global Community Forum , I wish there is a global consensus on what is acceptable ethics and what is not , for example it may be very ...
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RE: Biopsy In Anti Gbm Disease 20 hours ago
Question 1: pulmonary haemorrhage , anti gbm positive renal failure on Itu - just treat too unwell too biopsy? I would have no problem with that ...
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RE: Immunotactoid GN therapy (in a dog) 20 hours ago
While I agree with taking the ethicsl argument into consideration, I dont think it has a role here where the question was simply posed about what a...
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RE: Secondary cause for this TTP? 20 hours ago
aHUS v TTP without an ADAMSTS13 level? The seizures and perhaps the severe acute nature suggests TTP. The acute treatment may be the same but long ...
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RE: Tumor lysis syndrome diagnostic criteria, expert is needed 1 day ago
Thank you very much. ------------------------------ Naji Alhamid. Nephrologist Almawasat University Hospital. Damascus, Syria. [+951603382] -----...
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RE: Secondary cause for this TTP? 1 day ago
Thank you Dr. Glassock. I mean cobalamin C disease as a secondary cause of TMA. We transfused FFP ( other than PLEX) when he developed intracerebra...
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RE: Secondary cause for this TTP? 1 day ago
we measured protein not albumin in urine. But it measured after the first episode when hemolysis resolved and urinalysis was negative for hemoglobi...
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RE: Secondary cause for this TTP? 1 day ago
I agree with Dr. Venkat. I have seen marked proteinuria solely explained by hemoglobinuria in acute extra-vascular hemolysis (like malaria, G6PD de...
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RE: Secondary cause for this TTP? 1 day ago
Challenging question I believe that FFP and other blood components contain ADAMTS 13 and so by infusing them it will temporize the clinical situat...
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RE: Secondary cause for this TTP? 1 day ago
Do a UACR, it will be low if the proteinuria is due to hemoglobinuria. ------------------------------ Richard Glassock MD, FASN Emeritus Professor...
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RE: Secondary cause for this TTP? 1 day ago
12 grams is a lot and that is why a kidney biopsy will be valuable @Dr Venkat intersting your explanation of proteinuria based on hemoglobimiunria...
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RE: Secondary cause for this TTP? 1 day ago
Interesting. Would the platelet count respond to FFP alone, indicating a hereditary genetic deficiency of ADAMTS13.? -----------------------------...
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RE: Immunotactoid GN therapy (in a dog) 1 day ago
My curiosity was piqued. I can't find data on the range of K/L ratios in CD38 + Bone marrow B cells in normal dogs of varying inbred categories (su...
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RE: Secondary cause for this TTP? 1 day ago
C3 and C4 are normal. Replacement fluid was FFP. ------------------------------ Naji Alhamid. Nephrologist Kidney surgical Hospital. Damascus, Sy...
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RE: Immunotactoid GN therapy (in a dog) 1 day ago
It is not precisely correct to state that "dogs do not make kappa LC". Normal dogs, cats, horses and cows have B cells make 90% lambda And 10% kapp...
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RE: C3 Glomerulonephritis + Renal limited TMA - 24 yo F, Role of Eclizumab 1 day ago
I would agree- this patient seems to be a good candidate for Eculizumab therapy in addition to meticulous BP control. ----------------------------...
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RE: Biopsy In Anti Gbm Disease 1 day ago
Hi he never required dialysis creatinine stuck at 3.2. Don’t think we have been recording accurate urine output . Biopsy showed lm 41 gloms 24 acti...
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RE: Secondary cause for this TTP? 1 day ago
This level of serum homocysteine would be very commonly found in Advanced CKD of any etiology. If you are concerned about a hereditary from of TTP ...
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RE: Tumor lysis syndrome diagnostic criteria, expert is needed 1 day ago
Dear NajiFeel free to reach out to me at kdj200@gmail.comI can connect you with few experts in TLS in onconephrology Kenar Kenar D Jhaveri, MDProfe...
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RE: Secondary cause for this TTP? 1 day ago
Sounds more like TTP than cobalamin- C Disease. Have you used FFP infusion or Caplacizumab for therapy. Do you know what the aDAMTS13 activity leve...
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RE: Immunotactoid GN therapy (in a dog) 1 day ago
Noted information about fluctuations in UPr excretion in dogs. Relatively stable hypoalbuminemia suggests overall stable urine albumin loss. Howeve...
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RE: Secondary cause for this TTP? 1 day ago
Puzzled by 12 gram proteinuria. What was nature of proteinuria? Do you have a UAlb/Cr ratio and SAlb? While residual proteinuria is not uncommon af...
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