RE: Isolated Systolic Hypertension 4 minutes ago

Welcome back Dr. Aledan.  We have mussed you! ------------------------------ Richard Glassock MD, FASN Emeritus Professor David Geffen School of M...

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RE: Biopsy in patient with solitary kidney. 20 minutes ago

Have only read about it , but what about transjugular kidney biopsy --------------------------------- Dr. Hormaz Dastoor Nephrology Consultant Se...

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RE: Isolated Systolic Hypertension 1 hour ago

According to these studies, yes. CCB cause maximal pulse pressure reduction similar to ARB compared to other medications. ------------------------...

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RE: Biopsy in patient with solitary kidney. 5 hours ago

Dr. Chapagain: Is SCr still unchanged at 1.7 mg? Any change in urinalysis, urine sediment and urine Pr/Cr? Unless these trends are in a favorable d...

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RE: Biopsy in patient with solitary kidney. 8 hours ago

Thanks Dr. Whittier for your perspectives on this topic. Your experience and knowledge in this arena are very valuable and highly respected. If a b...

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RE: Biopsy in patient with solitary kidney. 9 hours ago

yes, very little data, small case series, but in experienced hands the trend is to try percutaneously.  I've done several myself.  As Dr. Glassock ...

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RE: Sodium Thiosulfate-PICC or Port 10 hours ago

what a difference a word makes, I am actually laughing out loud not just "lol", I was wondering about that bc we have talked about this before and ...

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RE: Isolated Systolic Hypertension 10 hours ago

The issue is how much of an effect CCB have on large vessel compliance in ISH. Some studies have shown that CCB improve vascular compliance and the...

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RE: Biopsy in patient with solitary kidney. 10 hours ago

It is very uncommon- but probably under-reported (for obvious reasons), my guess is about 1:10,000 for patients with two kidneys. I do not know the...

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RE: Xenograft Huge Advance 10 hours ago

A true milestone that has rippled around the globe. The funding should start pouring in. ------------------------------ Jonathan Slater MD Renal &...

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RE: Biopsy in patient with solitary kidney. 10 hours ago

@William Whittier bill is there any real data on this? ​ ------------------------------ Roger Rodby MD, FASN Professor of Medicine Rush Universit...

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RE: Biopsy in patient with solitary kidney. 10 hours ago

in the past there was some debate about open vs percutaneous kidney bx in patients with solitary kidney--- but it seems now the trend is to go ahea...

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RE: Sodium Thiosulfate-PICC or Port 10 hours ago

Depending on the dosage and interval, your patient may need only once a week HD, due to the fact that tiosulphate can be administered once weekly a...

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RE: Isolated Systolic Hypertension 13 hours ago

Studies from many years ago showed an approximately equal effect of a DHP-CCB (Amlodipine) on systolic and diastolic BP in hypertensive individuals...

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RE: Derms on HD II 14 hours ago

Clearly healing calciphylaxis. At this juncture I typically stop the STS and continue with Ca free Pi binders and calciimimetics indefinitely. ---...

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RE: Isolated Systolic Hypertension 14 hours ago

There are no guarantees SBP will fall and DBP will remain unchanged. ------------------------------ John Mellas MD Nephrology and Hypertension Spe...

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RE: Delayed Relapse of primary membranous with renal impairment unresponsive to Rituximab with bil. femoral AVN 14 hours ago

Thank you Dr. Glassock, Dr. Rodby and Dr. Venkat. I am planning to repeat US and kidney biopsy, and if it does not show significant scarring, repea...

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RE: Derms on HD II 15 hours ago

Hello to all colleagues Happy to do follow-up of this case. We have initiated Sodium thiosulfate 20% at a dose of 10 units ( total dose 2.5g) in o...

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RE: Derms on HD II 15 hours ago

Hello to all colleagues Happy to do follow-up of this case. We have initiated Sodium thiosulfate 20% at a dose of 10 units ( total dose 2.5g) in o...

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RE: Delayed Relapse of primary membranous with renal impairment unresponsive to Rituximab with bil. femoral AVN 15 hours ago

Dr. Pradhan: In my experience, in proteinuric renal disease, if SCr has been elevated and stable for more than a few weeks, immunosuppression usual...

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RE: IgA vasculitis 16 hours ago

This is a semantic issue and a Pandora’s Box of nomenclature. Here are my arguments. According to established criteria this patient can be classifi...

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RE: Isolated Systolic Hypertension 16 hours ago

My answer to your question about DBP and Amlodipine dosage isprobably yes. If he has a “sick sinus syndrome” and ISH should a pacemaker be consider...

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RE: Xenograft Huge Advance 17 hours ago

Robert Montgomery is a brilliant transplant physician and surgeon- had the opportunity to sit with him at a dinner presentation he gave at CEOT Mar...

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RE: Xenograft Huge Advance 17 hours ago

And as a bonus, the kidney recipient can get a pet pig to take home! ------------------------------ Lynn Cornell MD Mayo Clinic Rochester MN (507)...

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Use of IVIG in ABO incompatible desensitisation protocol 18 hours ago

A 27 year old male is on maintenance hemodialysis from past 8 months, cause of renal failure is not known. He is planned for ABO incompatible live ...

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RE: noncompliant dialysis patients 18 hours ago

If he is a large person it could be that his GFR is, say, 7-10 cc/min. It might be helpful in this particular case to review the reason why he bega...

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RE: noncompliant dialysis patients 19 hours ago

My original hypothesis was that his residual urine output could not be small as he was avoiding hospitals admissions. Labs report a Cr of 16, BUN 6...

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RE: Xenograft Huge Advance 19 hours ago

Although one can still argue about the ethics of "forcing" these pigs to be donors, wouldn't it be possible to harvest only one kidney so the donor...

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RE: Sodium Thiosulfate-PICC or Port 19 hours ago

I mistyped.  I do not find IP STS useful as it has numerous problems ------------------------------ Stuart Sprague DO, FASN Chief, Division of Nep...

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RE: IgA vasculitis 21 hours ago

The steroids were just started yesterday Sent from the all new AOL app for iOS

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RE: Isolated Systolic Hypertension 21 hours ago

Has sinus bradycardia Sometimes rate is 60 Will start on chlorthalidone But my question was will increasing calcium blocker apart from lowering s...

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RE: IgA vasculitis 22 hours ago

It is IgA vasculitis because of extrarenal signs and symptoms, but you bring up my point, if the IGAN is mild and the rash treated with dapsone, do...

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RE: Biopsy in patient with solitary kidney. 22 hours ago

I’d have to ask neurology. --------------------------------- Roger Rodby MD, FASN Professor of Medicine Rush University Medical Center Chicago IL...

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RE: Biopsy in patient with solitary kidney. 22 hours ago

any role for plasmapheresis, now that there is a possible CNS involvement --------------------------------- Dr. Hormaz Dastoor Nephrology Consult...

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RE: IgA vasculitis 22 hours ago

The renal biopsy is consistent with IgA Nephropathy, there is no mention of vasculitis ..I would not treat it with steroids . Yes , the patient doe...

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RE: Isolated Systolic Hypertension 1 day ago

Depending on cause of bradycardia,a pacemaker might help.  Beta blockers are contraindicated.  What about a low dose of a diuretic, like chlorthali...

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RE: Isolated Systolic Hypertension 1 day ago

What does his EKG show?  Is this a sinus bradycardia.  An increase in Stroke  Volume  is likely contributing to the increase in  systolic pressure ...

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RE: IgA vasculitis 1 day ago

But this is not IgAN it is IgAV-  I don't think  you can extrapolate therapies that  work in IgAN to IgAV. ------------------------------ Richard ...

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RE: IgA vasculitis 1 day ago

In the past we have used steroids and MMF in the Asian population with IgA nephropathy and > 1 gram of proteinuria Inevitably they relapse once the...

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RE: Sodium Thiosulfate-PICC or Port 1 day ago

Will likely need it for several months and I would suggest a port, changing to HD would be the best.  I also do find IP STS very useful ----------...

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RE: Xenograft Huge Advance 1 day ago

Yes it will be a game changer if successful. Hats off to Dr. Montgomery and his team for a splendid effort. We still have to wait and see --------...

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Isolated Systolic Hypertension 1 day ago

Quick question 78 year old Caucasian gentleman with a blood pressure 170/50-60 heart rate 45 to 55 range on lisinopril 20 mg and Amlodipine 2.5 mg...

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RE: Delayed Relapse of primary membranous with renal impairment unresponsive to Rituximab with bil. femoral AVN 1 day ago

“Thank you Dr. Rodby. What dose do you use when you use CyC alone?” 2 mg/kg/day if gfr nl --------------------------------- Roger Rodby MD, FASN...

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RE: Sodium Thiosulfate-PICC or Port 1 day ago

STS may be needed for months. Can a picc last that long? @Stuart Sprague --------------------------------- Roger Rodby MD, FASN Professor of Me...

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RE: Biopsy in patient with solitary kidney. 1 day ago

The yield is questionable. I’ve not had good luck with lung biopsy in GPA, lung very friable. --------------------------------- Roger Rodby MD, F...

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RE: Biopsy in patient with solitary kidney. 1 day ago

Thanks dr Rodby for ur input. Whats ur opinion on getting biopsy form the pulmonary nodule? ------------------------------ Bikash Chapagain MD Mid...

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RE: Biopsy in patient with solitary kidney. 1 day ago

Neurology does not have a clear cut diagnosis although they thought  it could be post infectious partial transverse myelitis, or GBS Like illness o...

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RE: Biopsy in patient with solitary kidney. 1 day ago

Thanks for the prompt response Dr Glassock. She also had vaginal bleeding( now resolved) so we did not really looked at her urinary sediment. She d...

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RE: IgA vasculitis 1 day ago

What has happened to her proteinuria with the prednisone? --------------------------------- Roger Rodby MD, FASN Professor of Medicine Rush Unive...

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RE: Biopsy in patient with solitary kidney. 1 day ago

I would probably just biopsy her. I know… If she refused I’d ask neurology how they feel about Emperic rituximab for her neurological disease that...

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