RE: Living Kidney Donor with Normal GFR, Small Kidneys 1 hour ago

Totally agree. Birth weight and prematurity are typically overlooked when looking at risk factors for CKD later in life. This should be considered....

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RE: severe hypercalcemia 3 hours ago

Interesting , but still does not explain her Pancytopenia ( was it transient ??) There is a study looking at the effects of absorption of Calcium ...

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RE: severe hypercalcemia 3 hours ago

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RE: severe hypercalcemia 4 hours ago

Hb 8.4g/dL, platelet 112 on day of dc . Unclear etiology. Plan is for outpatient BM bx. ------------------------------ Jennifer Waldmann MD Fellow...

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RE: severe hypercalcemia 4 hours ago

------------------------------ Jennifer Waldmann MD Fellow hackensack meridian howell NJ (732) 996-6741 ------------------------------

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RE: severe hypercalcemia 4 hours ago

Dr. Waldmann - many thanks for listing this follow up. Very good teaching point that Calcium Carbonate (+ Thiazides) can lead to severe hypercalcem...

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RE: Primary Vs secondary MGN 4 hours ago

Antibodies to NELL-1 are commonly found in the serum of patients with NELL-1 associated MN. I do not believe that an FDA approved Commercial assay ...

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RE: Primary Vs secondary MGN 5 hours ago

Thanks for all your comments. I did not prescribe a colonoscopy before, because his stool fit test was neg and no family history of cancer. I’ll ...

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RE: severe hypercalcemia 6 hours ago

It appears that it was induced by combination of tums and thiazide. Her pthrp was 16. 1,25 vit D suppressed. 25 vit D 27. Quite impressive. ------...

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RE: Anticoagulation duration after thromboembolic events in membraneous and lupus? 7 hours ago

Albumin is thought to be a good surrogate marker for these antithrombotic proteins , especially in Nephrotic Syndrome . I think it would just add t...

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RE: Anticoagulation duration after thromboembolic events in membraneous and lupus? 7 hours ago

Since one mechanism of thrombosis in nephrotic syndrome is urinary loss of antithrombotic proteins (C/S/antithrombin III) - is there any value in c...

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RE: Anticoagulation duration after thromboembolic events in membraneous and lupus? 9 hours ago

Sounds reasonable - but not supported by any evidence from a RCT- a 2C suggestion. Also remember that these thresholds are very dependent on the me...

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RE: severe hypercalcemia 11 hours ago

Any follow up on PTHrp, 1,25 Vit D levels or BM Biopsy  on this case ??? ------------------------------ Dr. Hormaz Dastoor Nephrology Consultant ...

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RE: Anticoagulation duration after thromboembolic events in membraneous and lupus? 11 hours ago

Seems that in Nephrotic Syndrome , any level of hypoalbuminemia  is a prothrombotic state . hence if a patient has had a VTE , then i would wait fo...

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RE: Antiphosphospholipid syndrom and renal impairment in SLE patient 14 hours ago

I am still confused as to why this patient is on steroids and Imuran. Is it because of APL or SLE or Both I am still not convinced that this patien...

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RE: Antiphosphospholipid syndrom and renal impairment in SLE patient 14 hours ago

I am still confused as to why this patient is on steroids and Imuran is it because of APL or SLE or Both I am still not convinced that this patient...

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RE: Oral supplements and membranous nephropathy 16 hours ago

A reasonably strong linkage exists between MS and MN (and -GBM Disease as well) ) based on common genes at the HLA locus on Chromosome 6. Thus, th...

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RE: Antiphosphospholipid syndrom and renal impairment in SLE patient 17 hours ago

Thank u very much --------------------------------- Wael Jebur MD, FASN drwaellatif@hotmail.com Dubai ---------------------------------

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RE: Entresto Plus RAASi 17 hours ago

As per the company.. the 103 mg of valsartan componant in 200mg of Entresto is bioequivalent to 160 mg of valsartan in Diovan. if u wich to increas...

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RE: Primary Vs secondary MGN 17 hours ago

Good point.  If found, it would  be a remarkably quick confirmation of these recent studies. ------------------------------ Richard Glassock MD, F...

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RE: ASN Mobile App? 18 hours ago

Thanks Dr. balan , that is really helpful ------------------------------ Rania Aburahma MBBS Abu Dhabi ------------------------------

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RE: Oral supplements and membranous nephropathy 18 hours ago

Thanks for sharing Dr.Rubin , that is interesting to know. ------------------------------ Rania Aburahma MBBS Abu Dhabi --------------------------...

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RE: Primary Vs secondary MGN 19 hours ago

In light of a recent post, need to make sure that the  patient is not taking over the counter lipoic acid supplements which can be associated with ...

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RE: Osteoporosis In Hemodialysis Patient 20 hours ago

I totally agree with Prof Glassock ------------------------------ Stuart Sprague DO, FASN Chief, Division of Nephrology and Hypertension NorthShor...

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RE: Primary Vs secondary MGN 21 hours ago

Sorry , I misread the IF for IgG subclasses.  This is IgG 1 dominant which raises the likelihood of NELL1 as Dr.Reen correctly points out.  This me...

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RE: Primary Vs secondary MGN 21 hours ago

It appears to be NELL 1 as IG1 predominant Malignancy work up needed --------------------------------- Bajinder Reen MD Brampton ON (905) 453-0...

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RE: Primary Vs secondary MGN 21 hours ago

This is likely PLA2R negative Primary MN.  It is unlikely to be NELL 1 due to IgG4 dominance THSD7A has been excluded.  It may be one of the rarer ...

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Primary Vs secondary MGN 21 hours ago

Need experts insight into understanding and management of this case. I am seeing from February 2021 a 46y otherwise healthy black male except a pos...

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RE: Biopsy In Small Sized Kidney 1 day ago

With 25 grams of daily protein excretion at this young age with progressive of kidney function and Hypoalbuminemia the most likely underlying lesio...

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RE: Osteoporosis In Hemodialysis Patient 1 day ago

I do not recommend doing a bone mineral density scan (DEXA scan) in patients on dialysis to assess “severity” of secondary hyperparathyroidism. Ser...

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RE: Biopsy In Small Sized Kidney 1 day ago

Massive proteinuria of 25 gm per day is usually noticeable with MCD although serum Albumin is not very low, but kidney size is small with loss of c...

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RE: Antiphosphospholipid syndrom and renal impairment in SLE patient 1 day ago

It was in an earlier response in this thread but here it is again https://pubmed.ncbi.nlm.nih.gov/20425532/ ------------------------------ Roge...

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RE: Osteoporosis In Hemodialysis Patient 1 day ago

Thank you all for your thoughts. Can we consider the findings of bone meniral density shown by DEXA SCAN as an indication of severity of renal bone...

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RE: Antiphosphospholipid syndrom and renal impairment in SLE patient 1 day ago

Thank you very much for your reply. . May you kindly share any relevant reference for that approach. --------------------------------- Wael Jebur...

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RE: Anticoagulation duration after thromboembolic events in membraneous and lupus? 1 day ago

Thanks Dr Glassock --------------------------------- Ashutosh Mahajan MD ---------------------------------

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RE: Reflux Nephropathy ? Superimposed GN 1 day ago

it seems proteinuria, creatinine and gross hematuria are all improving, but a biopsy may still be needed, see how things continue to progress, I su...

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RE: Antiphosphospholipid syndrom and renal impairment in SLE patient 1 day ago

"Her Antiphospholipid IgG titer is 4.9 ( normal is less than 1), currntly on prednisolon and Immuran. Dr. Rodby, is the progressive Chronic kidney ...

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RE: Mpo vasculitis treatment 1 day ago

how can you be sure this is a relapse, she got a lot of cyclophosphamide and I find it unusual that she would relapse already. Do you have MPO  lev...

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Mpo vasculitis treatment 1 day ago

Hi everyone, since April I have been treating a patient with renal vasculitis, who was initially dialysis dependent but quickly recovered. She is 8...

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RE: Antiphosphospholipid syndrom and renal impairment in SLE patient 1 day ago

Culture is positive for gram negatuve bacteria, but its recurrent, creatinine used to be hovering on 1.5_1.6mg/dl --------------------------------...

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RE: Antiphosphospholipid syndrom and renal impairment in SLE patient 1 day ago

Could we hear a bit more about the pyuria - considerations ? persistent ? differential white cell count culture for fastidious organisms/TB ...

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RE: Reflux Nephropathy ? Superimposed GN 1 day ago

Not convinced anti-PR3 antibody of 4.8 (upper limit of normal of 3.5) is significant. Should be repeated. Improvement in SCr without immunosuppress...

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RE: Reflux Nephropathy ? Superimposed GN 2 days ago

Just get back the following result: Anti-gbm negative C-anca negative < 1:20 P-anca negative < 1:20 Anti-mpo negative <9.0 Anti-pr3 positive 4.8 ( ...

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RE: Biopsy In Small Sized Kidney 2 days ago

Nephrotic range proteinuria make me thinking of MCD or membranouse Vs primary FSGS , Amylodosis with such small kidney is less likely , so if he ha...

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RE: Reflux Nephropathy ? Superimposed GN 2 days ago

The urine was pinkish bloody when examined- it was not dark bloody. At that time protein/creat was 7g. But note that urine creat was somewhat low o...

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RE: Reflux Nephropathy ? Superimposed GN 2 days ago

I have never ordered a urocrit. Dr. Wehbe: can you please update us on the course of your patient? 1. How bloody was the urine when your patient p...

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RE: Oral supplements and membranous nephropathy 2 days ago

I read that paper last night I asked one my family member to stop --------------------------------- Bajinder Reen MD Brampton ON (905) 453-082...

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RE: ASN Mobile App? 2 days ago

You can download the app called Member Centric and log on to the ASN part of it. All discussions can be accessed on that plus other features -----...

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RE: Living Kidney Donor with Normal GFR, Small Kidneys 2 days ago

I agree with inquiring about birth weight as part of living donor evaluation! Whether low birth weight history if everything else in the donor eval...

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RE: Reflux Nephropathy ? Superimposed GN 2 days ago

Getting a urocrit "aint happening" in my neck of the woods. But I like that approach, and I like using an albumin to creatinine ratio with it. One...

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