RE: Tarpeyo use in IgA Nephropathy patients with Low GFR 6 hours ago

As stated, we have no data that can provide a useful answer to your question- only anecdotes and opinions. It might help to know more about the spe...

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Tarpeyo use in IgA Nephropathy patients with Low GFR 6 hours ago

Hello Neph Community, Has anyone had good success with using Tarpeyo in patients with GFR in the 20's? The cut off in trials has been >30, so ...

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RE: Calling All Nephrologists: What's Your Workflow Wisdom? 10 hours ago

In the era of the EMR, I use it when I get a consult, within five minutes reviewing the case, labs etc etc then I put in preliminary orders for wha...

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RE: Calling All Nephrologists: What's Your Workflow Wisdom? 1 day ago

I have been doing this for a long time and have a few suggestions. Never take anything for granted and question everything you are told. I firs...

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RE: atypical Anti GBM 1 day ago

This patient had findings compatible with Atypical anti-GBM disease. In this condition, the evidence (so far) for a "need" to give immunosuppresiiv...

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RE: Renal biopsy for low C4, and history of subacute cutaneous lupus, ANA positive 1: 320 and speckled but C3, urinalysis, double-stranded DNA antibody are normal , urine protein undetectable and creatinine stable > 1 year 1 day ago

Agreed No indication for a kidney biopsy in this patient. ------------------------------ Richard Glassock MD, FASN Laguna Woods CA (949) 388-8885...

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RE: atypical Anti GBM 1 day ago

@prof glassock based on the biopsy there is an element of activity . Would not that mean we need to immunosuppress? Thanks ----------------------...

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RE: Treatment of Membranous glomerulonephritis - clinically low risk with renal biopsy showing advanced chronicity 1 day ago

Thank you 😊 --------------------------------- Alaa Nabih Abdalla nephrology fellow Egypt --------------------------------- [More]

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RE: Treatment of Membranous glomerulonephritis - clinically low risk with renal biopsy showing advanced chronicity 1 day ago

Deposits that are rarefied or becoming licentious by EM indicate ongoing reabsorption of the deposits. Small usual density deposits immediately und...

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RE: Treatment of Membranous glomerulonephritis - clinically low risk with renal biopsy showing advanced chronicity 1 day ago

Thank u dr fogo for clarification My Q in EM does deposits type radiolucent or radio dense help to distinguish non active from active disease ---...

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RE: Renal biopsy for low C4, and history of subacute cutaneous lupus, ANA positive 1: 320 and speckled but C3, urinalysis, double-stranded DNA antibody are normal , urine protein undetectable and creatinine stable > 1 year 1 day ago

No evidence of active lupus nephritis supported by normal urine ..no hematuria ..and stable ckd Only c4 is low and it happened before without clin...

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RE: Treatment of Membranous glomerulonephritis - clinically low risk with renal biopsy showing advanced chronicity 1 day ago

The spikes are a matrix reaction from podocytes to deposits. Spikes mean that the deposits have been there long enough to result in a visible matri...

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RE: ATI, Anuria post kidney transplant 1 day ago

Given nephrotic range proteinuria but low normal serum albumin - would get urine protein electrophoresis and if confirms primarily urine albuminuri...

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Renal biopsy for low C4, and history of subacute cutaneous lupus, ANA positive 1: 320 and speckled but C3, urinalysis, double-stranded DNA antibody are normal , urine protein undetectable and creatinine stable > 1 year 1 day ago

White gentleman age 76 reports having lupus for decades since 1992 but never had kidney biopsy that he can remember. Remembers biopsy of skin decad...

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RE: Hypokalaemia in dialysis patient 1 day ago

Daily urine output? Potassium concentration in urine? Medications? Laboratory method for potassium? ------------------------------ Giovanni Can...

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RE: Hypokalaemia in dialysis patient 1 day ago

Be careful- hyperlipidemia may interfere with the accurate estimation of electrolyte levels, including Potassium, in lipemic plasma. -----------...

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Hypokalaemia in dialysis patient 1 day ago

51 years old female patient known case of hypertension, medullary sponge kidney, distal RTA , severe hypertriglycerdiemia with recurrent hypokal...

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RE: Calling All Nephrologists: What's Your Workflow Wisdom? 2 days ago

I have 3 bits of advice: It is so easy to become complacent and complacency generates mediocrity. There is nothing wrong with mediocrity, almost no...

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RE: ATI, Anuria post kidney transplant 2 days ago

Encouraging that renal function has recovered in this previously anuric/dialysis-dependent patient. Increase in UPr/Cr to ~ 8 g/g from prior level...

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RE: ATI, Anuria post kidney transplant 2 days ago

No rituximab was given till now This was my question actually bases on the stable condition now apart from proteinuria -------------------------...

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RE: ATI, Anuria post kidney transplant 2 days ago

No just received 6 sessions after the 1st biopsy This was about 3 weeks before the last FUP labs --------------------------------- Ahmed Emara M...

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RE: Treatment of Membranous glomerulonephritis - clinically low risk with renal biopsy showing advanced chronicity 2 days ago

Do the spikes suggest active immunologic disease or could this still (in the absence of EM to distinguish) be Stage 4, inactive immunologically? ...

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RE: Calling All Nephrologists: What's Your Workflow Wisdom? 2 days ago

Dear Dr. Zapata, When consulting in the hospital or in the office , something that worked well for me for 40 years was: 1) take a look at the ...

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RE: ATI, Anuria post kidney transplant 2 days ago

No just received 6 sessions after the 1st biopsy This was about 3 weeks before the last FUP labs --------------------------------- Ahmed Emara M...

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RE: Treatment of Membranous glomerulonephritis - clinically low risk with renal biopsy showing advanced chronicity 3 days ago

Pregnancy can be considered as a reasonable test for renal reserve. I would like to know what was the reason for the C section. If it was not relat...

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RE: Calling All Nephrologists: What's Your Workflow Wisdom? 3 days ago

The answer is already inside your question. You have a good structure of thinking. You need nothing else but keep reading. I will try to attach a f...

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Calling All Nephrologists: What's Your Workflow Wisdom? 3 days ago

As a newly practicing nephrologist, I find myself reflecting on the transition from fellowship to independent practice. While fellowship lays the f...

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Seeking Research Opportunities for ASN Conference Abstract Submission 3 days ago

Dear Members of the ASN Community, I hope this message finds you well. My name is Amna Zaheer, and I am a 3rd-year medical student at Liaquat Nat...

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RE: ATI, Anuria post kidney transplant 3 days ago

Is your patient still receiving plasmapheresis and if so, how often, has he been treated with retuximab? ------------------------------ [Mark] ...

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RE: Treatment of Membranous glomerulonephritis - clinically low risk with renal biopsy showing advanced chronicity Thursday, December 5 @ 11:45 PM

Thanks, as I made a correction earlier, hypertension was diagnosed only 3 months ago for complaint of headache. She had her third child birth with ...

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RE: ATI, Anuria post kidney transplant Thursday, December 5 @ 10:55 PM

Yes exactly We tested UPCR many times after the 1st time it ranged from 8-10 gm/gm S. Albumin sometimes was mildly low (3.2 - 3.3) but last read...

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RE: Treatment of Membranous glomerulonephritis - clinically low risk with renal biopsy showing advanced chronicity Thursday, December 5 @ 1:57 PM

The chronicity and MN could be 2 different things. Does she have any history suggestive of developmental reduced nephron number (very low birth wei...

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RE: ATI, Anuria post kidney transplant Thursday, December 5 @ 12:30 PM

"UPCR ~8 gm" Dr. Emara: please clarify. Since SCr is now 0.8 mg and SAlb is 3.5 g, is the UPr/Cr really hugher (8 g vs. 2.2 g/g before) Thanks....

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RE: ATI, Anuria post kidney transplant Thursday, December 5 @ 12:00 PM

@K.K. Venkat @Mark Lerman --------------------------------- Ahmed Emara MD, MBChB, FASN Ain shams University Cairo 00201006721401 -------------...

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RE: Treatment of Membranous glomerulonephritis - clinically low risk with renal biopsy showing advanced chronicity Thursday, December 5 @ 10:37 AM

Thanks Drs. Glassock and Rodby for prompt response. There is one correction in the history. Hypertension was discovered only 3 months ago for compl...

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RE: Treatment of Membranous glomerulonephritis - clinically low risk with renal biopsy showing advanced chronicity Thursday, December 5 @ 7:03 AM

I agree in general with Dr. Rodby's comments. However, very chronic PLA2R associated MN , an a full spontaneous immunological remission but with ma...

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RE: Treatment of Membranous glomerulonephritis - clinically low risk with renal biopsy showing advanced chronicity Thursday, December 5 @ 6:30 AM

I would bet we wont be able to get any more information on specific staining for NELL1 exostosin etc. 3 grams of proteinuria, not nephrotic syndr...

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RE: Treatment of Membranous glomerulonephritis - clinically low risk with renal biopsy showing advanced chronicity Thursday, December 5 @ 4:59 AM

I would not characterize this patient as having low risk pMN. We do not know which diagnostic subcategory of "Primary " MN most likely is present i...

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RE: ATI, Anuria post kidney transplant Thursday, December 5 @ 2:58 AM

Last update EM just back : 100% effacement of FP ! Last FUP creat 0.8 S.albumin 3.5 gm/dl No edema UPCR ~8 gm FK 8 On Tac/MMF/Psl What's your...

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Treatment of Membranous glomerulonephritis - clinically low risk with renal biopsy showing advanced chronicity Thursday, December 5 @ 2:01 AM

33 y/o lady physician, a mother of 3 children, is known hypertensive for 3 years. A recent abdominal ultrasound for some unrelated reason showed no...

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RE: Minimal Change- FSGS treatment resistance Wednesday, December 4 @ 5:31 PM

I second Dr. Glassock concern about sensitivity of PET. Recurrence is a possibility, did the oncologist do flow cytometry? Was his initial lymph...

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RE: atypical Anti GBM Wednesday, December 4 @ 3:50 PM

Addendum- in the absence of crescents in the kidney biopsy, the treatment of this condition is very uncertain and no RCT have been performed. Som...

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RE: atypical Anti GBM Wednesday, December 4 @ 3:16 PM

This case has all of the "ear-marks" of what has been called "Atypical anti-GBM disease"; namely, - mesangiopathic GN without Crescents, linear IgG...

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atypical Anti GBM Wednesday, December 4 @ 1:18 PM

I saw 52-year-old female patient on 10/6/24 with hypothyroidism, vitamin D deficiency, asthma, migraine, s/p hysterectomy and arthritis in hands, H...

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Kidney Week 2025 Content Suggestions due Dec 11 Wednesday, December 4 @ 12:00 PM

ASN is soliciting session suggestions for next year's meeting. Each suggestion must include the content and faculty for a complete session. To sub...

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Kidney Week 2025 Content Suggestions due Dec 11 Wednesday, December 4 @ 12:00 PM

ASN is soliciting session suggestions for next year's meeting. Each suggestion must include the content and faculty for a complete session. To sub...

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Kidney Week 2025 Content Suggestions due Dec 11 Wednesday, December 4 @ 12:00 PM

ASN is soliciting session suggestions for next year's meeting. Each suggestion must include the content and faculty for a complete session. To sub...

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Kidney Week 2025 Content Suggestions due Dec 11 Wednesday, December 4 @ 12:00 PM

ASN is soliciting session suggestions for next year's meeting. Each suggestion must include the content and faculty for a complete session. To sub...

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Kidney Week 2025 Content Suggestions due Dec 11 Wednesday, December 4 @ 12:00 PM

ASN is soliciting session suggestions for next year's meeting. Each suggestion must include the content and faculty for a complete session. To sub...

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Kidney Week 2025 Content Suggestions due Dec 11 Wednesday, December 4 @ 12:00 PM

ASN is soliciting session suggestions for next year's meeting. Each suggestion must include the content and faculty for a complete session. To sub...

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