ASN represents more than 21,000 kidney health professionals working to help people with kidney diseases and their families. Created with input from all of ASN's constituencies, the new ASN logo allows the society to continue our growth and work toward a goal of a world without kidney diseases.
The latest Nephrology Self-Assessment Program (nephSAP) issue, Volume 22: Issue 2 (Aug 2023): End-Stage Kidney Disease is now available online.
RE: Immune Complex Mediated MPGN In Addict 17 minutes ago
Short of the TEE that was refused & what's already been reported, how thorough was the search for an occult & chronic infection in this IDU, e.g. S...
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RE: Crescentic GN in a patient with known infective endocarditis 59 minutes ago
Is he oliguric? I have occasionally advocated treating an IRGN once the infection has cleared , but I just dont see doing it here. You can only...
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RE: Hyperphosphatemic, nonazotemic CAT with calcified paw pads 1 hour ago
Question- could this all be due to inadequate therapy of hyperthyroidism -what is the TSH , free T3 and T4 levels. Just speculating. ------------...
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RE: Hyperphosphatemic, nonazotemic CAT with calcified paw pads 1 hour ago
I think this could fit with the equivalent of familial tumoral calcinosis from an inactivating mutation in klotho (or in FGFR or somewhere else fur...
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Hyperphosphatemic, nonazotemic CAT with calcified paw pads 3 hours ago
Hi everyone, I'd love to get your thoughts on this patient we have with very unique skin lesions. It was referred to us by a dermatologist who...
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RE: Immune Complex Mediated MPGN In Addict 4 hours ago
The suggestion of Dr. Fogo needs attention. Also , the results of LC monotypic deposition needs to be addressed. I agree tgat an IRGN is likely, bu...
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RE: Crescentic GN in a patient with known infective endocarditis 4 hours ago
Although the presence of VRE endocarditis provides a good explanation for the Crescentic GN, the advanced COPD at a young age raises the issue of a...
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RE: APKD and ? FMD 5 hours ago
I had a patient with ADPKD and Ehlers Danlos syndrome, vascular type. I regarded this as a coincidental finding following review of the literature,...
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RE: APKD and ? FMD 6 hours ago
Hi, I did attach CTangiogram and Doppler ultrasound reports, please have a look. Also attached MRI brain report. I have not confirmed the diag...
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RE: Immune Complex Mediated MPGN In Addict 6 hours ago
I fully understand your concerns about adding MMF, RTX or other IS agents to the steroid regimen already being used in thus active I'V drug-abuser....
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RE: trial of peritoneal dialysis in presence of diabetic gastroparesis 8 hours ago
Managing gastroparesis while on PD is very frustrating! These patients develop fluid, electrolytes problems, and poor solid intake further deterior...
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RE: Immune Complex Mediated MPGN In Addict 9 hours ago
Did deposits stain for IgM? ------------------------------ Agnes Fogo Professor Vanderbilt University Medical Center Nashville TN (615) 322-3114 ...
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RE: APKD and ? FMD 9 hours ago
Nice case. However is the diagnosis of FMD based on Doppler results alone? Doppler is a good screening test but can by no means confirm renal arter...
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Crescentic GN in a patient with known infective endocarditis 9 hours ago
Good morning: I have an interesting case and a clinical dilemma. The patient is now in house, 46 male, admitted on 9/27/23 for AKI with prese...
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RE: APKD and ? FMD 9 hours ago
Thank you, appreciate the guidance, we are screening. Keeping in mind also if this can just be intimate tear and injury related infarction ? I am a...
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RE: Immune Complex Mediated MPGN In Addict 9 hours ago
Thank you prof. Glassock Thank you Dr mohamed But this first time to meet iv drug abuser who require immunosuppressants Is it safe to give hime im...
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RE: IgA nephropathy 10 hours ago
Dr. Venkat is quite correct- and he raises a very important point-a form of spontaneously reversible AKI has been seen and reported repeatedly in c...
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RE: IgA nephropathy 12 hours ago
Thank you Dr Venkat: no RBC casts reported. ------------------------------ Eithan Orlev-Shitrit MD MONTGOMERY OH (513) 488-6279 ----------------...
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RE: IgA nephropathy 12 hours ago
Thank you Dr Glassock for the detailed answer! It is alcoholic liver cirrhosis, no exposure to silica per his profession ( food engineering). -...
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RE: IgA nephropathy 12 hours ago
Gross hematuria in the setting of IgA nephropathy - any recent COVID infection or vaccination? Given gross hematuria + AKI + possible coagulopafh...
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RE: APKD and ? FMD 13 hours ago
Good case with ADPKD with incidental renal artery stenosis . We think incidental renal artery stenosis need to sure hemodynamic significant by meas...
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RE: Immune Complex Mediated MPGN In Addict 13 hours ago
Good and nice presentation of immune complex mediated MpGN , although the prognosis is poor but in our clinical practice we proceed for active ther...
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RE: Immune Complex Mediated MPGN In Addict 15 hours ago
Also please recheck the kidney biopsy concerning monotypic Light Chain deposition-- this was not reported . If you can, It might help to stain the ...
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RE: Immune Complex Mediated MPGN In Addict 15 hours ago
Tough case. Assuming that all features of infection are absent and ANCA testing is also negative, I Might try MMF and tapering of steroids, or poss...
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RE: Immune Complex Mediated MPGN In Addict 16 hours ago
Hi all Prof. Glassock RF negative Cryo negative Hep Viro negative Patient on high dose steroid has generalized anasarca Albumin 20 , 24 h protei...
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APKD and ? FMD 16 hours ago
I have a 19 year old who presented post MVA with thoracic fractures and lung injury and incidentally we found interesting pathology. She had a fami...
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RE: IgA nephropathy 17 hours ago
A partial answer to your good question can be found in a recently published paper by Li, W et al in Am J Nephrol (2023). In a single center center ...
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IgA nephropathy 19 hours ago
I have a 43 year old male with history of liver cirrhosis who was seen for gross hematuria. At presentation Cr was 1.3 ( 1.0 a year before), UPCR 1...
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RE: trial of peritoneal dialysis in presence of diabetic gastroparesis 1 day ago
Just the gastroparesis problem, thanks, Mark PLEASE NOTE: This message is intended for the use of the person to whom it is addressed. It may cont...
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RE: trial of peritoneal dialysis in presence of diabetic gastroparesis 1 day ago
Mark, You mean in diabetic gastroparesis, or in general? Klemens Klemens B. Meyer, MD Professor of Medicine, Tufts University School of Medicin...
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RE: trial of peritoneal dialysis in presence of diabetic gastroparesis 1 day ago
In my clinical experience, the potential benefit of PD has not panned out, and esophageal reflux can become severe and dominate the upper gastroint...
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RE: Serum Bicarbonate Concentration in Hyponatremic SIADH Patients 1 day ago
Thank you Dr. Soleimani. Much appreciated. ------------------------------ Mario Rubin, M.D. Houston TX (713) 252-5539 ---------------------------...
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RE: Serum Bicarbonate Concentration in Hyponatremic SIADH Patients 1 day ago
Thank you, Dr. Rubin for the interesting question. The AVPR1 (or V1R to the field of nephrology) is an understudied gene in the field of nephrology...
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RE: Treatment of recurrent minimal change disease 1 day ago
Should this lady get a genetic study done? She doesn't satisfy the usual criteria for doing a genetic study but the increasing resistance to treatm...
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Nephrology Teaching in Private Practice 1 day ago
Hi, I am a nephrologist in private practice at a large community hospital (that has evolved into a tertiary care center) with a residency progra...
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RE: Serum Bicarbonate Concentration in Hyponatremic SIADH Patients 1 day ago
Thank you Dr. Solemaini for the added educational pearls. Is there a molecular difference between the V1 receptor in smooth muscle (mainly responsi...
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RE: Treatment of recurrent minimal change disease 1 day ago
She seems rituximab responsive. I do not routinely follow IgG levels on Rituximab, is that something others do? MMF (+/- CNI) may keep her in...
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RE: trial of peritoneal dialysis in presence of diabetic gastroparesis 1 day ago
My experience has been similar to that of others. In general PD instillation worsened "subjectively" to the patient the feeling inadequate gastric ...
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Calciphylaxis vs warfarin skin necrosis 1 day ago
77 WF s/p mechanical AVR/MVR 2010, a-fib/flutter s/p MAZE, HTN, pHTN and CKD stage 4. Two month hx progressive lateral thigh lesions starting as p...
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RE: polycystic kidney disease which is not PKD1/2 related 1 day ago
A additional reason for genetic testing is PGD (preimplantation genetic diagnosis). ------------------------------ Ella Koifman-Zeltzer MD Tel-Av...
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RE: C3 glomerulopathy ? 1 day ago
Thanks for this great insight. In the meantime , while creatinine is still 1.34; microhematuria -5/HPF ACR 848, PCR 1373 HG up to 13.2 fro...
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RE: trial of peritoneal dialysis in presence of diabetic gastroparesis 1 day ago
I don't know why, but I can't remember any PD patient with severe gastroparesis. ------------------------------ Raymond Krediet MD, PhD Academic ...
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RE: Treatment of recurrent minimal change disease 1 day ago
Combination of tacrolimus + mycophenolate may work? May permit lower trough levels of tacrolimus. Also tacrolimus interaction may increase mycophen...
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RE: trial of peritoneal dialysis in presence of diabetic gastroparesis 1 day ago
We use in our case of diabetic kidney disease with gastroparesis , icodextrin based solution at night with 1.36% solution 3 times a day . We follow...
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RE: Treatment of recurrent minimal change disease 1 day ago
It a lot if data bearing in this question but I would try to get her back into a full or partial remission with RTX, and then start MMF for relapse...
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RE: Serum Bicarbonate Concentration in Hyponatremic SIADH Patients 1 day ago
Thank you, Dr. Rubin for your cheerful comment. The nephrology literature has had a dearth of information on V1 receptor in the kidney collecting d...
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Treatment of recurrent minimal change disease 1 day ago
I have a 31 year old female who has had recurrent nephrotic syndrome. Originally seen in 2021 and had kidney biopsy which revealed diffuse podocyto...
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RE: trial of peritoneal dialysis in presence of diabetic gastroparesis 2 days ago
Very interesting anecdote- did you use glucose or icodextrin containing solutions. Most of the literature and Dr. Bargman's experience suggest that...
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RE: C3 glomerulopathy ? 2 days ago
A pattern of injury of MPGN has been associated with Buckley Syndrome, first described by Lagrue 1982 (long before the description of C3GN). These ...
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RE: trial of peritoneal dialysis in presence of diabetic gastroparesis 2 days ago
I have one case referred from GI specialist that 45years old female with diabetic kidney disease and severe gastroparesis . We preceed with CAPD , ...
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