ASN represents more than 21,000 kidney health professionals working to help people with kidney diseases and their families. Created with input from all of ASN's constituencies, the new ASN logo allows the society to continue our growth and work toward a goal of a world without kidney diseases.
The latest Nephrology Self-Assessment Program (nephSAP) issue, Volume 22: Issue 1 (Apr 2023): Disorders of Divalent Ions, Renal Bone Disease and Nephrolithiasis is now available online.
SGLT2 inhibitor role in non proteinuric CKD 1 minutes ago
I stopped an SGLT2 inhibitor on a patient and I wanted to get thoughts from others in this forum. A 76 yr old female with a long standing history...
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RE: Ozempic+statin= rhabdo 14 minutes ago
I can't find any information about weight based dosage for adults for rosuvastatin, please help with any references. As a separate issue I did see...
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RE: Accepting applications: Li-Li Hsiao Leadership Fellowship 2 hours ago
For some reason I was not able to open the link or send an email using these "Application: docs.google.com/document/d/1hr… Or email win@womeninneph...
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RE: Open Forum 2 hours ago
Suggestions to enhance postings: 1. Periodic emails to ALL ASN members from the ASN president's office reminding members about the availability of ...
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RE: Open Forum 3 hours ago
Dear Dr Glassock An interesting problem. I suggest that you retrospectively collect several years of data monkey and see what the pattern is. ...
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RE: Open Forum 3 hours ago
A colleague of mine made the same comment about twitter yesterday. Maybe it is just a summer lull. Our in-patient consult service usually runs ...
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RE: lymph leakage in a patient on peritoneal dialysis 3 hours ago
"HI, Dr. Glassock, After two months, I am back to report the follow ups.For the past two months, we have slowly liberated her diet, off amlodi...
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SGLT 2 inhibitors in renal transplant patients 4 hours ago
I want to offer apologies if this discussion already happened before. How is the data for SGLT 2 inhibitors in renal transplant patients without ...
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RE: lymph leakage in a patient on peritoneal dialysis 5 hours ago
HI, Dr. Glassock, After two months, I am back to report the follow ups. For the past two months, we have slowly liberated her diet, off amlodip...
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Join us! Polycystic Kidney Disease Research Resource Consortium Virtual Science Round Table 5 hours ago
Please join us for the Polycystic Kidney Disease Research Resource Consortium (PKD RRC) monthly science round table, Monday June 5, 2023 4PM EST. O...
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Open Forum 11 hours ago
The posting rate on the Open Forum has always been a cyclical matter. But the cycles seem to be getting deeper with time and the duration of the na...
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Accepting applications: Li-Li Hsiao Leadership Fellowship 19 hours ago
Applications for the Li-Li Hsiao Leadership Fellowship are now open! More information: docs.google.com/document/d/1Yz… Application: docs.google.co...
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RE: PLA2R negative Membranous Nephropathy- Management Q 1 day ago
I misread. I thought it was memebranous with igkappa restriction on biopsy --------------------------------- Bajinder Reen MD Brampton ON (905) ...
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RE: Blastomycosis And kidney Injury 1 day ago
Interesting issue. Like COVID very difficult to prove causality. GN us exceptionally rare in sporadic cases of Blastomycosis . An association of th...
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Blastomycosis And kidney Injury 1 day ago
Hi, Is there any evidence to state that blastomycosis can cause gn? We have been dealing with a blastomycosis outbreak in upper Michigan and I th...
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RE: PLA2R negative Membranous Nephropathy- Management Q 1 day ago
The main reason to do IgG subclass staining in PLA2R negative MN is to narrow the search for specific antigens (e.g. NELL -, THDS7A , etc.) . Beyon...
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RE: PLA2R negative Membranous Nephropathy- Management Q 1 day ago
You need ig subclass If it is one subclass then treat as primary If more than two subclass r:o lymphoproliferayive disorder --------------------...
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RE: PLA2R negative Membranous Nephropathy- Management Q 1 day ago
Update: This patient with PLA2R negative Membranous Nephropathy underwent a BM biopsy, it came back as negative for Waldenstroms or myloma. Co...
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RE: Alkaline urine in primary hyperaldosteronism 1 day ago
Similar to the urine pH in rodents in lab investigations the most accurate method is via pH microelectrode. Indicator pH papers are not very accura...
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RE: Alkaline urine in primary hyperaldosteronism 1 day ago
How do we accurately measure urine pH? Can we rely on urine dipstick only? ------------------------------ V. Melnikov MD, FASN NW Kaiser Permane...
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RE: ANCA negative pauci immune GN. ANA, anti dsDNA positive. Low complements. 1 day ago
"Dr. Rodby: If ANCA-positive pauci-immune GN can occur in a patient with SLE, it is also possible that ANCA-negative pauci-immune GN can also occur...
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RE: IgAN vs postinfectious 1 day ago
South Asian. Worse prognosis Maybe it might work/. You will know in a few months time.. keep us in the loop. ------------------------------ Richa...
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RE: Alkaline urine in primary hyperaldosteronism 1 day ago
I agree that direct measurement of NH4+ would be desirable though I do wonder if that day were to come whether the nephrology community would be re...
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RE: IgAN vs postinfectious 1 day ago
She is of Indian origin.
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RE: IgAN vs postinfectious 1 day ago
Adding Myfortic at this stage is not unreasonable, UtcI would not expect much benefit as she is non-Asia.b. I nonof no new trials of my ophenolate ...
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RE: IgAN vs postinfectious 1 day ago
She is 50 kg and I started her on 25 mg prednisone daily, and then added losartan and SGLT2i. Her UPCR initially improved from max of 6g/g to 1.4 g...
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RE: ANCA negative pauci immune GN. ANA, anti dsDNA positive. Low complements. 1 day ago
Most pauci-immune GNs have been found to be ANCA positive, but 10–30% of the cases could be ANCA negative (1). ANCAs are detected by indirect immun...
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RE: ANCA negative pauci immune GN. ANA, anti dsDNA positive. Low complements. 1 day ago
really good question, we used to think that immune complex lupus GN (subendothelial deposits)would have hypocomplementia but pauci immune lupus GN ...
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RE: combined rejection 1 day ago
Thanks for all ur kind feedbacks, ACR 335, repeated DSA not done. ------------------------------ Ahmed Mahedy MD Banha Faculty of Medicine Banha ...
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RE: ANCA negative pauci immune GN. ANA, anti dsDNA positive. Low complements. 2 days ago
Thanks Dr Venkat. This happened last week and waiting to get updated results of urine and complements. ------------------------------ Saurabh Go...
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RE: ANCA negative pauci immune GN. ANA, anti dsDNA positive. Low complements. 2 days ago
Thanks for your response Dr Rodby. I want to avoid cyclophosphamide in this young female with creatinine already improved to 1.3. Do you see hypoco...
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RE: Should a potential living kidney donor with NAFLD/ NASH be accepted? 2 days ago
Now we have a diagnosis and prognosis for the liver disease present in the prospective kidney donor. What's next? ------------------------------ ...
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RE: Dialysis dependent lupus nephritis 2 days ago
Dr. Png: Thanks for providing a long-term update on this patient's course. Residual SCr of 3.95 mg. Is he a small or large individual? Renal functi...
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RE: Dialysis dependent lupus nephritis 2 days ago
Further follow up on this case: after completion of IV cyclophosphamide, he was started on mycophenolate mofetil 500 mg BID, and maintained on pre...
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RE: Should a potential living kidney donor with NAFLD/ NASH be accepted? 2 days ago
Follow up on this case: Hepatologist proceeded with liver biopsy, showing NASH CRN histological scoring system 2 (steatosis score 1 (15-30%), lobu...
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RE: Combined ANA, ANCA and PLA2R serology 2 days ago
SCr of 1.6 mg is worrisome, unless it is already decreasing. Also, if SCr is stable from day-to-day, it means all the creatinine generated daily is...
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RE: Combined ANA, ANCA and PLA2R serology 2 days ago
The serology (ANA and ANCA) is complicated because if Hydralazine use- but the Anti-PLA2R + probably means that MN is present that will Need therap...
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RE: Ozempic+statin= rhabdo 2 days ago
In that case, a long shot but you may want to check for anti-HMGCR autoantibody. --------------------------------- Oded Friedman -----------------...
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RE: Combined ANA, ANCA and PLA2R serology 2 days ago
that ANCA titer is non specific, need an MPO and PR3 Elisa P/C ratio may not be reliable in the setting of AKI with what sounds like ATN from the ...
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RE: Combined ANA, ANCA and PLA2R serology 2 days ago
On hydralazine 10 mg per cardiologist and p-ANCA titer was around 1:640 ------------------------------ Laith Al dahabreh MD Leesburg GA (216) 856...
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RE: Alkaline urine in primary hyperaldosteronism 2 days ago
We will be happy to do that. It is going to be either in July or August. I will forward the zoom link. Warm regards, --------------------------...
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RE: Alkaline urine in primary hyperaldosteronism 2 days ago
Doctor Bhave is raising a very interesting point in regards to the role of hypokalemia in enhancing NH4+ excretion, and possibly in generating meta...
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RE: Ozempic+statin= rhabdo 2 days ago
Yes she had diffuse myslgias which are minimally getting bett ------------------------------ Jeffrey Lautman MD Cleveland Kidney & Hypertension C...
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RE: Yellow Fever Vaccine For Lupus Nephritis Patient In Complete Remission 2 days ago
Yellow fever virus vaccine is a live but attenuated vaccine that is contraindicated in immunosuppressed patients.. I assume that he has been in a C...
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RE: Ozempic+statin= rhabdo 2 days ago
Did she present with muscle weakness in addition to myalgia and if so, has it persisted despite stopping rosuvastatin? ---------------------------...
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Yellow Fever Vaccine For Lupus Nephritis Patient In Complete Remission 2 days ago
A 35-year-old man with lupus nephritis, now in complete remission on MMF 1000 mg bid l, HCQ 200 mg bid and prednisolone 5 mg od. He want to travel...
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RE: Alkaline urine in primary hyperaldosteronism 2 days ago
If possible, your division should make the lecture available to this audience via zoom. Thank you. Mario
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RE: Alkaline urine in primary hyperaldosteronism 2 days ago
Agree little data on ammonium excretion in primary hyperaldosteronism. The only paper that addresses this clearly is the 1965 Japanese paper with 2...
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RE: ANCA negative pauci immune GN. ANA, anti dsDNA positive. Low complements. 2 days ago
SCr improved from ~ 5 mg to 1.3 mg/dL. AKI might have spuriously increased the UPr/Cr ratio. What are the current UPr/Cr, complement and anti-DS DN...
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RE: ANCA negative pauci immune GN. ANA, anti dsDNA positive. Low complements. 2 days ago
Pauci immune pathology is not unusual with SLE, in fact although SLE is often considered the consummate immune complex disease, I think we see the ...
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