SGLT2 inhibitor role in non proteinuric CKD 1 minutes ago

I stopped an SGLT2 inhibitor on a patient and I wanted to get thoughts from others in this forum. A 76 yr old female with a long standing history...

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RE: Ozempic+statin= rhabdo 14 minutes ago

I can't find any information about weight based dosage for adults for rosuvastatin, please help with any references. As a separate issue I did see...

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RE: Accepting applications: Li-Li Hsiao Leadership Fellowship 2 hours ago

For some reason I was not able to open the link or send an email using these "Application: docs.google.com/document/d/1hr… Or email win@womeninneph...

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RE: Open Forum 2 hours ago

Suggestions to enhance postings: 1. Periodic emails to ALL ASN members from the ASN president's office reminding members about the availability of ...

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RE: Open Forum 3 hours ago

Dear Dr Glassock An interesting problem. I suggest that you retrospectively collect several years of data monkey and see what the pattern is. ...

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RE: Open Forum 3 hours ago

A colleague of mine made the same comment about twitter yesterday. Maybe it is just a summer lull. Our in-patient consult service usually runs ...

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RE: lymph leakage in a patient on peritoneal dialysis 3 hours ago

"HI, Dr. Glassock, After two months, I am back to report the follow ups.For the past two months, we have slowly liberated her diet, off amlodi...

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SGLT 2 inhibitors in renal transplant patients 4 hours ago

I want to offer apologies if this discussion already happened before. How is the data for SGLT 2 inhibitors in renal transplant patients without ...

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RE: lymph leakage in a patient on peritoneal dialysis 5 hours ago

HI, Dr. Glassock, After two months, I am back to report the follow ups. For the past two months, we have slowly liberated her diet, off amlodip...

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Join us! Polycystic Kidney Disease Research Resource Consortium Virtual Science Round Table 5 hours ago

Please join us for the Polycystic Kidney Disease Research Resource Consortium (PKD RRC) monthly science round table, Monday June 5, 2023 4PM EST. O...

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Open Forum 11 hours ago

The posting rate on the Open Forum has always been a cyclical matter. But the cycles seem to be getting deeper with time and the duration of the na...

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Accepting applications: Li-Li Hsiao Leadership Fellowship 19 hours ago

Applications for the Li-Li Hsiao Leadership Fellowship are now open! More information: docs.google.com/document/d/1Yz… Application: docs.google.co...

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RE: PLA2R negative Membranous Nephropathy- Management Q 1 day ago

I misread. I thought it was memebranous with igkappa restriction on biopsy --------------------------------- Bajinder Reen MD Brampton ON (905) ...

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RE: Blastomycosis And kidney Injury 1 day ago

Interesting issue. Like COVID very difficult to prove causality. GN us exceptionally rare in sporadic cases of Blastomycosis . An association of th...

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Blastomycosis And kidney Injury 1 day ago

Hi, Is there any evidence to state that blastomycosis can cause gn? We have been dealing with a blastomycosis outbreak in upper Michigan and I th...

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RE: PLA2R negative Membranous Nephropathy- Management Q 1 day ago

The main reason to do IgG subclass staining in PLA2R negative MN is to narrow the search for specific antigens (e.g. NELL -, THDS7A , etc.) . Beyon...

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RE: PLA2R negative Membranous Nephropathy- Management Q 1 day ago

You need ig subclass If it is one subclass then treat as primary If more than two subclass r:o lymphoproliferayive disorder --------------------...

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RE: PLA2R negative Membranous Nephropathy- Management Q 1 day ago

Update: This patient with PLA2R negative Membranous Nephropathy underwent a BM biopsy, it came back as negative for Waldenstroms or myloma. Co...

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RE: Alkaline urine in primary hyperaldosteronism 1 day ago

Similar to the urine pH in rodents in lab investigations the most accurate method is via pH microelectrode. Indicator pH papers are not very accura...

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RE: Alkaline urine in primary hyperaldosteronism 1 day ago

How do we accurately measure urine pH? Can we rely on urine dipstick only? ------------------------------ V. Melnikov MD, FASN NW Kaiser Permane...

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RE: ANCA negative pauci immune GN. ANA, anti dsDNA positive. Low complements. 1 day ago

"Dr. Rodby: If ANCA-positive pauci-immune GN can occur in a patient with SLE, it is also possible that ANCA-negative pauci-immune GN can also occur...

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RE: IgAN vs postinfectious 1 day ago

South Asian. Worse prognosis Maybe it might work/. You will know in a few months time.. keep us in the loop. ------------------------------ Richa...

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RE: Alkaline urine in primary hyperaldosteronism 1 day ago

I agree that direct measurement of NH4+ would be desirable though I do wonder if that day were to come whether the nephrology community would be re...

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RE: IgAN vs postinfectious 1 day ago

She is of Indian origin.

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RE: IgAN vs postinfectious 1 day ago

Adding Myfortic at this stage is not unreasonable, UtcI would not expect much benefit as she is non-Asia.b. I nonof no new trials of my ophenolate ...

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RE: IgAN vs postinfectious 1 day ago

She is 50 kg and I started her on 25 mg prednisone daily, and then added losartan and SGLT2i. Her UPCR initially improved from max of 6g/g to 1.4 g...

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RE: ANCA negative pauci immune GN. ANA, anti dsDNA positive. Low complements. 1 day ago

Most pauci-immune GNs have been found to be ANCA positive, but 10–30% of the cases could be ANCA negative (1). ANCAs are detected by indirect immun...

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RE: ANCA negative pauci immune GN. ANA, anti dsDNA positive. Low complements. 1 day ago

really good question, we used to think that immune complex lupus GN (subendothelial deposits)would have hypocomplementia but pauci immune lupus GN ...

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RE: combined rejection 1 day ago

Thanks for all ur kind feedbacks, ACR 335, repeated DSA not done. ------------------------------ Ahmed Mahedy MD Banha Faculty of Medicine Banha ...

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RE: ANCA negative pauci immune GN. ANA, anti dsDNA positive. Low complements. 2 days ago

Thanks Dr Venkat. This happened last week and waiting to get updated results of urine and complements. ------------------------------ Saurabh Go...

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RE: ANCA negative pauci immune GN. ANA, anti dsDNA positive. Low complements. 2 days ago

Thanks for your response Dr Rodby. I want to avoid cyclophosphamide in this young female with creatinine already improved to 1.3. Do you see hypoco...

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RE: Should a potential living kidney donor with NAFLD/ NASH be accepted? 2 days ago

Now we have a diagnosis and prognosis for the liver disease present in the prospective kidney donor. What's next? ------------------------------ ...

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RE: Dialysis dependent lupus nephritis 2 days ago

Dr. Png: Thanks for providing a long-term update on this patient's course. Residual SCr of 3.95 mg. Is he a small or large individual? Renal functi...

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RE: Dialysis dependent lupus nephritis 2 days ago

Further follow up on this case: after completion of IV cyclophosphamide, he was started on mycophenolate mofetil 500 mg BID, and maintained on pre...

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RE: Should a potential living kidney donor with NAFLD/ NASH be accepted? 2 days ago

Follow up on this case: Hepatologist proceeded with liver biopsy, showing NASH CRN histological scoring system 2 (steatosis score 1 (15-30%), lobu...

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RE: Combined ANA, ANCA and PLA2R serology 2 days ago

SCr of 1.6 mg is worrisome, unless it is already decreasing. Also, if SCr is stable from day-to-day, it means all the creatinine generated daily is...

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RE: Combined ANA, ANCA and PLA2R serology 2 days ago

The serology (ANA and ANCA) is complicated because if Hydralazine use- but the Anti-PLA2R + probably means that MN is present that will Need therap...

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RE: Ozempic+statin= rhabdo 2 days ago

In that case, a long shot but you may want to check for anti-HMGCR autoantibody. --------------------------------- Oded Friedman -----------------...

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RE: Combined ANA, ANCA and PLA2R serology 2 days ago

that ANCA titer is non specific, need an MPO and PR3 Elisa P/C ratio may not be reliable in the setting of AKI with what sounds like ATN from the ...

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RE: Combined ANA, ANCA and PLA2R serology 2 days ago

On hydralazine 10 mg per cardiologist and p-ANCA titer was around 1:640 ------------------------------ Laith Al dahabreh MD Leesburg GA (216) 856...

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RE: Alkaline urine in primary hyperaldosteronism 2 days ago

We will be happy to do that. It is going to be either in July or August. I will forward the zoom link. Warm regards, --------------------------...

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RE: Alkaline urine in primary hyperaldosteronism 2 days ago

Doctor Bhave is raising a very interesting point in regards to the role of hypokalemia in enhancing NH4+ excretion, and possibly in generating meta...

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RE: Ozempic+statin= rhabdo 2 days ago

Yes she had diffuse myslgias which are minimally getting bett ------------------------------ Jeffrey Lautman MD Cleveland Kidney & Hypertension C...

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RE: Yellow Fever Vaccine For Lupus Nephritis Patient In Complete Remission 2 days ago

Yellow fever virus vaccine is a live but attenuated vaccine that is contraindicated in immunosuppressed patients.. I assume that he has been in a C...

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RE: Ozempic+statin= rhabdo 2 days ago

Did she present with muscle weakness in addition to myalgia and if so, has it persisted despite stopping rosuvastatin? ---------------------------...

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Yellow Fever Vaccine For Lupus Nephritis Patient In Complete Remission 2 days ago

A 35-year-old man with lupus nephritis, now in complete remission on MMF 1000 mg bid l, HCQ 200 mg bid and prednisolone 5 mg od. He want to travel...

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RE: Alkaline urine in primary hyperaldosteronism 2 days ago

If possible, your division should make the lecture available to this audience via zoom. Thank you. Mario

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RE: Alkaline urine in primary hyperaldosteronism 2 days ago

Agree little data on ammonium excretion in primary hyperaldosteronism. The only paper that addresses this clearly is the 1965 Japanese paper with 2...

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RE: ANCA negative pauci immune GN. ANA, anti dsDNA positive. Low complements. 2 days ago

SCr improved from ~ 5 mg to 1.3 mg/dL. AKI might have spuriously increased the UPr/Cr ratio. What are the current UPr/Cr, complement and anti-DS DN...

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RE: ANCA negative pauci immune GN. ANA, anti dsDNA positive. Low complements. 2 days ago

Pauci immune pathology is not unusual with SLE, in fact although SLE is often considered the consummate immune complex disease, I think we see the ...

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