ASN represents more than 21,000 kidney health professionals working to help people with kidney diseases and their families. Created with input from all of ASN's constituencies, the new ASN logo allows the society to continue our growth and work toward a goal of a world without kidney diseases.
The latest Nephrology Self-Assessment Program (nephSAP) issue, Volume 21: Issue 1 (Apr 2022): Acute Kidney Injury and Critical Care Nephrology is now available online.
RE: AKI after living related kidney transplant 10 hours ago
@Gaurav GuptaI am interested in your recommendation for a low salt diet ? Given history of AKI which improved with IV fluids? --------------------...
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RE: Dual ANCA + anti-GBM + 13 hours ago
“Is this ant-GBM antibody Disease with simultaneous ANCA, or ANCA Associated Vasculitis with a positive anti-GBM antibody?” Who knows? — and I do n...
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RE: Dual ANCA + anti-GBM + 19 hours ago
"Up to one third of patients with antiGBM anti bodies also have ANCAs (usually myeloperoxi dase ANCA).8,9" (NEJM attached) I...
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RE: Dual ANCA + anti-GBM + 20 hours ago
Dr Glassock. How often do you see ANCA positivity in anti-GBM disease and does it play any role in the renal injury ? Thank you ------------------...
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RE: Dual ANCA + anti-GBM + 21 hours ago
The risk of DAH is greatly decreased in non-smokers but not to zero. If the patient is a non-smoker I think the risk of subsequent development of D...
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RE: Dual ANCA + anti-GBM + 22 hours ago
Is he a cigarette smoker? Dr. Glassock: is it correct to say that pulmonary hemorrhage from anti-GBM antibody is very unlikely in non-smokers? If h...
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RE: Dual ANCA + anti-GBM + 22 hours ago
Great discussion I believe that anti GBM disease with single positivity will relapse less than dual positivity. So on way to conceive management o...
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RE: AKI after living related kidney transplant 23 hours ago
Yes, Foley was placed for 4 days with similar creatinine Get Outlook for iOS
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RE: Dual ANCA + anti-GBM + 1 day ago
Interesting question. The likelihood of a clinically important inmpricemeny in kidney function with maximal therapy Sterouds, CYC, PLEX) is small b...
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RE: Dual ANCA + anti-GBM + 1 day ago
Thank you Dr Glassock If we decide not to treat, is there a risk of lung involvement further down the line? Do you suggest treating MPO positivity ...
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RE: AKI after living related kidney transplant 1 day ago
Excuse if already discussed- given history of self catherization pretransplant- has intermittent lower tract obstruction been excluded by placing f...
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RE: vit d supplement 1 day ago
I totally agree ------------------------------ Stuart Sprague DO, FASN Chief, Division of Nephrology and Hypertension NorthShore University Health...
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RE: Dual ANCA + anti-GBM + 1 day ago
With dialysis- dependency and greatly elevated SCr at start of steroids the expected outcome will likely be poor, irrespective of therapy , but if ...
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RE: Endocarditis GN 1 day ago
I fully agree with Dr. Venkat. Proper therapy of the staph infection must take first priority here, IMO. --------------------------------- Richard...
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RE: Dual ANCA + anti-GBM + 1 day ago
Thank you, Dr Glassock Still passing 1-1.5 liters/day (Pt weight 90kg) pre-dialysis creatinine is around 800 sorry should have said, he was pulsed...
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RE: vit d supplement 1 day ago
Thanks Dr. Sprague- there are many misconceptions about the proper use of DEXA scanning in CKD 3,4 and 5. My general impression is that it is an ov...
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RE: Dual ANCA + anti-GBM + 1 day ago
Is the patient oligo-anuric? If so the Chances of recovery, even with optimal treatment, are very low (because of dialysis dependency and 100% cres...
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RE: vit d supplement 1 day ago
I agree with many of the comments, I would say that in general if the GFR is > 45, there is absolutely no need for activated D and may cause proble...
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RE: AKI after living related kidney transplant 1 day ago
Thank you.
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Dual ANCA + anti-GBM + 1 day ago
60 year caucasian gentleman presented with 2 months of lethargy, fatigue, loss of appetite. Admission Creat 567mmol/l, UO 1litre, progressive incre...
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RE: Endocarditis GN 1 day ago
Regardless of whether this patient has C3-dominant, infection-associated GN (staphylococcal, source-endocarditis) or an unrelated C3 glomerulopathy...
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RE: AKI after living related kidney transplant 1 day ago
In Dent Disease-1, besides the proximal tubule, there are transport abnormalities in the Loop of Henle and collecting ducts also. The following cas...
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RE: Endocarditis GN 1 day ago
It seems likely that both of these cases had post-streptococcal GN- high ASLOT, Low C3 with normal or near normal C4 and a compatible Kidney Biopsy...
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RE: Endocarditis GN 1 day ago
I do agree that there is place here for pronase treated IF. Great case and challenging one .I wouldn't use IS at least for now So motivating that...
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Communities app is working again 1 day ago
Dear All, The Communities app seems to be working properly now. It should now allow you to login and access the discussions. Sorry again for th...
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RE: AKI after living related kidney transplant 1 day ago
Great insights Dr Venkat Many good points but still confused to some extent or i may be missing something: This disease is a proximal disease not...
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RE: AKI after living related kidney transplant 1 day ago
Caveat: With current SCr of 4.9 mg/dL in the recipient, LMW proteinuria may be due to tubular injury from causes other than Dent Disease. Also, the...
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RE: AKI after living related kidney transplant 1 day ago
In a predominantly tubulo-interstitial/hypercalciuric disorder such as Dent Disease, episodes of AKI developing and resolving (at least partially) ...
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RE: AKI after living related kidney transplant 1 day ago
I reproduce my reply from the AST forum here: This is a fascinating case. My summary and thoughts are as follows: Since Dent's disease is an X-lin...
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RE: Endocarditis GN 1 day ago
I realize that the Main reason for performing Paraffin IF is to search for concealed monoclonal Ig deposits, but some cases C3 dominant GN by Froze...
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RE: AKI after living related kidney transplant 1 day ago
Sure i see your point but the symptoms are quite atypical for Dent To follow and hope to have some update ------------------------------ Samir Mal...
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RE: AKI after living related kidney transplant 1 day ago
@Samir Mallat I agree that Dents will not recur in the allograft but it may if the donor kidney is also affected. As I said it is possible that the...
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RE: AKI after living related kidney transplant 1 day ago
tough case.If Slow graft function persists can consider -imaging all vessels (CTA, CTV ) -Persisting ATI with unclear cause can at times be from ab...
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RE: Endocarditis GN 1 day ago
Interesting story, reads like treated endocarditis and then GN delayed after treatment, BUT still bacteremic so not so surprising that the GN is no...
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RE: Communities App failing again 1 day ago
From the "Reply" tab you really have two options. If you just click on truly you are replying to the community and it will show up here as I am doi...
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RE: Endocarditis GN 1 day ago
Tough case. Probably has a smoldering abscess somewhere (myocardial, peri-valvular?). With an active staphylococcal infection, steroids nay be harm...
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Endocarditis GN 1 day ago
Colleagues We have a case here of 43 y/o white male IVDA MRSA IE ( TV and Pulm valve Dx'd 4 wks ago) Tx with vanoc then switched to Dapto ( no...
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RE: Communities App failing again 1 day ago
In addition I have to admit that it is not a very friendly user platform and I need to log in to ASN every time I get a mail …or I may be doing som...
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RE: AKI after living related kidney transplant 2 days ago
Creatinine is 4.9, negative BK PCR, DSA negative. Get Outlook for iOS
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RE: Biopsy In Anti Gbm Disease 2 days ago
Thank you Dr Glassock Sure it helps
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RE: Biopsy In Anti Gbm Disease 2 days ago
The short term renal prognosis is about the same for pure anti-GBM antibody and Combined ANCA and anti-GBM. The combined disease may have a somewha...
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RE: Communities App failing again 2 days ago
The recurring App failures are very frustrating and a source of much embarrassment, as the ASN is believed to be very adept at handling communicati...
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RE: vit d supplement 2 days ago
Value of DEXA scanning in early stage CKD is problematical, but might help to determine need for bisphosphonates (which should be used with great c...
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RE: Refractory anti-GBM disease 2 days ago
Thanks for your reply! I did also question if perhaps we should continue trying to treat given the lack of IF/TA and hope for kidney salvage, but t...
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RE: Refractory anti-GBM disease 2 days ago
Thanks so much for your insights! After lengthy discussion with the patient, that is exactly what we planned to do. Just wanted to make sure it was...
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RE: vit d supplement 2 days ago
If GFR is normal, can't see a rationale for using active vitamin-D analog. In early stages of CKD (1 to 3), most patients will have enough 1-alpha ...
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RE: AKI after living related kidney transplant 2 days ago
What is status of allograft (creat) on belatacept and MMF. have you been following ddcfDNA in this patient. What is BK PCR ? ---------------------...
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TMA and eculizumab 2 days ago
Dear ASN community experts, This is a controversial question that I am going to post. But, would love to have discussion on this : Would you con...
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RE: vit d supplement 2 days ago
No reasons to use activated Vitamin D in early CKD stages 1 or 2 or 3 .May consider them at later stage 4 or 5 specially if severe disease I will ...
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Communities App failing again 2 days ago
Sorry y'all. This recurring problem is at least as frustrating to the ASN as it is to you and Dr Glassock and of course me. What else can I say. T...
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