ASN's Mission

To create a world without kidney diseases, the ASN Alliance for Kidney Health elevates care by educating and informing, driving breakthroughs and innovation, and advocating for policies that create transformative changes in kidney medicine throughout the world.

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email@asn-online.org

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About ASN

AKINow Journal Club

Tuesday, January 23, 2024 | 12:00 PM – 1:00 PM EST

Hosted by the American Society of Nephrology

Featured article: Teprasiran, a Small Interfering RNA, for the Prevention of Acute Kidney Injury in High-Risk Patients Undergoing Cardiac Surgery: A Randomized Clinical Study 

PubMed. 2021 Oct 5;144(14):1133-1144. https://pubmed.ncbi.nlm.nih.gov/34474590/. Epub 2021 Sep 3.

In this article:

    Acute kidney injury (AKI) affects up to 30% of patients undergoing cardiac surgery, leading to increased in-hospital and long-term morbidity and mortality. Teprasiran is a novel small interfering RNA that temporarily inhibits p53-mediated cell death that underlies AKI. In this study, The incidence, severity, and duration of early AKI in high-risk patients undergoing cardiac surgery were significantly reduced after teprasiran administration. 

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    Faculty

              Bruce A. Molitoris, MD, MS, FASN
         Bruce A. Molitoris, MD, MS, FASN
           Indiana University School of Medicine 
                               Alexander Zarbock
                                      Univ.- Professor Dr. med. Alexender Zarbock
                            University Hospital Münster 

    Moderators

    Amandeep Bajwa
    Amandeep Bajwa, PhD
    The University of Tennessee Health Science Center
                                  Sherry Mansour
                              Sherry Mansour, MD, MS
                              Yale School of Medicine

    Questions?

    If you have questions about this webinar, please contact Bonnie Freshly, Senior Project Specialist for Excellence in Patient Care, at bfreshly@asn-online.org

    For more about ASN, and EPC, visit our website at epc.asn-online.org.