AKINow Journal Club
Tuesday, January 23, 2024 | 12:00 PM – 1:00 PM EST
Hosted by the American Society of Nephrology
Featured article: Teprasiran, a Small Interfering RNA, for the Prevention of Acute Kidney Injury in High-Risk Patients Undergoing Cardiac Surgery: A Randomized Clinical Study
PubMed. 2021 Oct 5;144(14):1133-1144. https://pubmed.ncbi.nlm.nih.gov/34474590/. Epub 2021 Sep 3.
In this article:
Acute kidney injury (AKI) affects up to 30% of patients undergoing cardiac surgery, leading to increased in-hospital and long-term morbidity and mortality. Teprasiran is a novel small interfering RNA that temporarily inhibits p53-mediated cell death that underlies AKI. In this study, The incidence, severity, and duration of early AKI in high-risk patients undergoing cardiac surgery were significantly reduced after teprasiran administration.
Faculty
Moderators
Questions?
If you have questions about this webinar, please contact Bonnie Freshly, Senior Project Specialist for Excellence in Patient Care, at bfreshly@asn-online.org
For more about ASN, and EPC, visit our website at epc.asn-online.org.