Basic/Clinical Science Session

Leveraging T Cells and Macrophages in Glomerular Diseases

November 10, 2019 | 10:00 AM - 12:00 PM

Location: 146 A/B, Walter E. Washington Convention Center

Session Description

T cells and macrophages have taken a back seat during the development of targeted therapeutics for autoimmune and glomerular diseases. This session reviews recent advances in the understanding of T-cell and macrophage biology as they relate to autoimmune and glomerular diseases and the implications of using T-cell and macrophage biology to design new therapeutic approaches to glomerular disease.

Learning Objective(s)

  • Describe how T cells may be targeted to treat glomerular diseases
  • Explain how macrophages may be targeted to treat glomerular diseases

Learning Pathway(s)

  • Glomerular Diseases
  • Pathology


  • Salem Almaani, MD, MS, FASN
  • Ingeborg M. Bajema, MD, PhD


  • Chimeric Antigen Receptor (CAR) T Cells in Glomerulonephritis
    10:00 AM - 10:30 AM
    A. Richard Kitching, MBChB, PhD, FASN 
  • T Cell Exhaustion in Autoimmunity
    10:30 AM - 11:00 AM
    Eoin F. McKinney, MBChB, PhD
  • Disease Flares in ANCA-Associated GN: Urine Analysis of Macrophage Activation
    11:00 AM - 11:30 AM
    Peter Heeringa, PhD
  • Diabetic Nephropathy: Can We Prevent Disease Progression by Targeting the Macrophages?
    11:30 AM - 12:00 PM
    Charles E. Alpers, MD