Basic/Clinical Science Session

Kidney Diseases in Africa: Insight from the H3-Africa Kidney Disease Research Network

November 08, 2019 | 02:00 PM - 04:00 PM

Location: 147, Walter E. Washington Convention Center

Session Description

The H3AFRICA kidney disease research network (H3AFRICA KDRN) consortium was established to develop the first Pan-African study to understand the genetic architecture of CKD in Africa and build capacity for genomic research on the continent. The consortium recently completed a case control study of the genetic epidemiology of CKD in Africa in more than 8000 participants, and the group is currently enrolling a cohort study that will further explore the genetic and morphologic spectrum of CKD in Africa.

Learning Objective(s)

  • Explain the logistics of establishing a cohort of patients for a longitudinal study of CKD in resource-poor setting
  • Describe the different studies being carried out by the H3AFRICA KDRN consortium and opportunities for future collaborative studies
  • Describe the epidemiology of APOL1 nephropathy in African patients
  • Discuss the existing variable patterns of management of nephrotic syndrome in Africa and the need for the development of a baseline uniform management practice as a prerequisite for natural history and genomic studies

Learning Pathway(s)

  • Genetic Diseases of the Kidneys
  • Chronic Kidney Disease


  • Marva M. Moxey-Mims, MD, FASN
  • Akinlolu O. Ojo, MD, PhD, MPH, FASN