Basic/Clinical Science Session

CircRNA, lncRNA, eRNA, and miRNA: New Functions of Noncoding RNAs

November 09, 2019 | 04:30 PM - 06:30 PM

Location: 147, Walter E. Washington Convention Center

Session Description

High-throughput DNA sequencing has revealed that most of the human genome is transcribed into RNA, much of which has little or no protein-coding potential. So-called noncoding RNAs include short microRNAs (miRNA) that inhibit mRNA translation and long noncoding RNAs (lncRNA) that regulate transcription and post-transcriptional gene expression. More recently, eRNAs associated with gene enhancers and unexpected circular forms of RNA (circRNA) have been identified. This session provides an update on noncoding RNAs and examples of lncRNAs in CKD and miRNAs in kidney development.

Learning Objective(s)

  • Describe the structures and functions of noncoding RNA
  • Discuss the roles of noncoding RNAs in diabetic nephropathy and kidney development

Learning Pathway(s)

  • Genetic Diseases of the Kidneys
  • Development and Pediatrics

Moderators

  • Karam S. Aboudehen, PhD
  • Jordan A. Kreidberg, MD, PhD

Presentations

  • MicroRNAs in PKD
    04:30 PM - 05:00 PM
    Ronak Lakhia, MD
  • Unconventional RNA Forms: Circular RNA
    05:00 PM - 05:30 PM
    Jeremy E. Wilusz, PhD
  • Long Noncoding RNAs and CKD
    05:30 PM - 06:00 PM
    Farhad R. Danesh, MD, FASN
  • MicroRNAs in the Developing Kidney
    06:00 PM - 06:30 PM
    Jacqueline Ho, MD