Functional Proteomics: Unraveling Molecular Machines to Protein Networks in Metabolic Disease
November 08, 2019 | 10:30 AM - 12:30 PM
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Basic/Clinical Science Session
Functional Proteomics: Unraveling Molecular Machines to Protein Networks in Metabolic Disease
November 08, 2019 | 10:30 AM - 12:30 PM
Location: 206, Walter E. Washington Convention Center
Session Description
Functional proteomics is a study of protein function that advances understanding of the mechanistic pathways of disease pathogenesis. A variety of mass spectrometry-based approaches allows characterization of cellular protein assemblies and subsequent assignment of individual proteins to specific molecular machines, pathways, and networks, according to an increasing level of organizational complexity. This session discusses the application of these techniques to understand metabolic basis of kidney diseases.
Learning Objective(s)
- Explain top-down proteomic technologies to characterize protein networks
- Discuss the role of post-translational protein acylation in metabolic diseases
- Describe the role of functional proteomics in renal pathophysiology
- Discuss the application of functional proteomics to biomarker discovery in diabetic kidney disease
Learning Pathway(s)
- Diabetes and Metabolism
- Glomerular Diseases
Moderators
- John M. Arthur, MD, PhD, FASN
- Anna Vachaparampil Mathew, MBBS
Presentations
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Harnessing the Power of Top-Down Proteomics to Determine Protein Function
10:30 AM - 11:00 AM
Ying Ge, PhD
Harnessing the Power of Top-Down Proteomics to Determine Protein Function
November 08, 2019 | 10:30 AM - 11:00 AM
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Metabolic Regulation by Protein Acylation
11:00 AM - 11:30 AM
Yingming Zhao, PhD
Metabolic Regulation by Protein Acylation
November 08, 2019 | 11:00 AM - 11:30 AM
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Functional Proteomics and Applications to the Pathophysiology of Metabolic Kidney Disease
11:30 AM - 12:00 PM
Markus M. Rinschen, MD
Functional Proteomics and Applications to the Pathophysiology of Metabolic Kidney Disease
November 08, 2019 | 11:30 AM - 12:00 PM
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Inflammatory Proteome and Risk for Progression of Diabetic Kidney Disease
12:00 PM - 12:30 PM
Monika A. Niewczas, MD, PhD, MPH
Monika A. Niewczas, MD, PhD, MPH
Inflammatory Proteome and Risk for Progression of Diabetic Kidney Disease
November 08, 2019 | 12:00 PM - 12:30 PM
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