ASN's Mission

ASN leads the fight to prevent, treat, and cure kidney diseases throughout the world by educating health professionals and scientists, advancing research and innovation, communicating new knowledge, and advocating for the highest quality care for patients.

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1401 H St, NW, Ste 900, Washington, DC 20005

email@asn-online.org

202-640-4660

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Kidney Week

Basic/Clinical Science Session

Reversal of Kidney Diseases: Lessons from Diabetic and Nondiabetic Renal Injury

October 24, 2020 | 02:30 PM - 04:30 PM

Location: Live-Streamed

Session Description

Diabetic kidney disease is a major health burden for patients with diabetes. Recent discoveries of multiple reno-protective drugs will enable us to slow progressive renal decline and delay onset of ESKD. However, it is becoming more apparent that therapeutic goals should be to stop progressive renal decline and, if possible, restore renal function. In this session, experts in clinical and experimental research present possibilities and limitations in accomplishing such goals.

Learning Objective(s)

  • Describe human model of reversal of diabetic structural kidney lesions with regards to pancreas transplant
  • Describe human model of reversal of functional impairment of renal function with regards to bariatric surgery
  • Discuss results in animal models that showed short-term regression of glomerulosclerosis is possible but it does not persist during longer observation
  • Explain the cellular and molecular mechanisms of the novel macula densa cell-mediated glomerular tissue remodeling process and its alterations in diabetes

Learning Pathway(s)

  • Diabetes and Metabolism
  • Chronic Kidney Disease

Moderators

  • Charles E. Alpers, MD
  • M. Luiza A. Caramori, MD, MS, PhD

Presentations

  • Pancreas Transplantation in Type 1 Diabetes: A Human Model of Reversal of Diabetic Renal Lesions
    02:30 PM - 03:00 PM
    Michael Mauer, MD
  • Bariatric Surgery: Emerging Therapy to Reverse Kidney Diseases in Severe Obesity
    03:00 PM - 03:30 PM
    Petter Bjornstad, MD 
  • Can We Reverse Diabetic Kidney Disease? Potential and Limitations
    03:30 PM - 04:00 PM
    Agnes B. Fogo, MD
  • Beyond Hemodynamics: Macula Densa Cells Orchestrate Glomerular Tissue Remodeling and Repair
    04:00 PM - 04:30 PM
    Janos Peti-Peterdi, MD, PhD