ASN's Mission

ASN leads the fight to prevent, treat, and cure kidney diseases throughout the world by educating health professionals and scientists, advancing research and innovation, communicating new knowledge, and advocating for the highest quality care for patients.

learn more

Contact ASN

1401 H St, NW, Ste 900, Washington, DC 20005


The Latest on Twitter

Kidney Week

Basic/Clinical Science Session

Advanced Systems to Maintain Mineral Balance

October 24, 2020 | 02:30 PM - 04:30 PM

Location: Simulive

Session Description

Calcium, phosphate, and magnesium are multivalent cations that are important for many biologic and cellular functions. The kidneys play a central role in the homeostasis of these electrolytes. When body stores of these ions decline significantly, gastrointestinal absorption, bone resorption, and renal tubular reabsorption increase to normalize their levels. This session discusses new mechanistic concepts in how calcium, phosphate, and magnesium are handled by the kidneys.

Learning Objective(s)

  • Describe calcium homeostasis in tubular cells
  • Characterize phosphate transport in the proximal tubule
  • List the causes of renal hypomagnesemia
  • Discuss mechanisms of magnesium homeostasis and the interplay of kidney and intestine

Learning Pathway(s)

  • Bone and Mineral Metabolism
  • Cell and Transport Physiology


  • Chou-Long Huang, MD, PhD
  • Rukshana Shroff, MD, PhD


  • Phosphate Acts Directly on the Calcium-Sensing Receptor to Stimulate Parathyroid Hormone Secretion
    02:30 PM - 03:00 PM
    Donald T, Ward, PhD 
  • Npt2a Inhibition Reduces Plasma Phosphate in Mice with Normal and Reduced Kidney Function
    03:00 PM - 03:30 PM
    Jessica Dominguez Rieg, PhD
  • Mutations in ATP1A1 Cause Renal Hypomagnesemia, Refractory Seizures, and Intellectual Disability
    03:30 PM - 04:00 PM
    Karl P. Schlingmann, MD
  • Epithelial Magnesium Transport by TRPM6 and TRPM7 in Kidney and Intestine
    04:00 PM - 04:30 PM
    Vladimir Chubanov, PhD