ASN's Mission

ASN leads the fight to prevent, treat, and cure kidney diseases throughout the world by educating health professionals and scientists, advancing research and innovation, communicating new knowledge, and advocating for the highest quality care for patients.

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1401 H St, NW, Ste 900, Washington, DC 20005


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Kidney Week

Basic/Clinical Science Session

Unraveling Novel Molecular Targets in Diabetic Kidney Disease

October 24, 2020 | 10:00 AM - 12:00 PM

Location: On-Demand

Session Description

Several new potential therapeutic targets have emerged in recent studies in model systems of diabetic kidney disease (DKD), including immune regulators, mitochondrial activators, and improved endothelial function. This session addresses these novel mechanistic studies and potential for translation.

Learning Objective(s)

  • Describe novel mechanistic targets for DKD treatment
  • Discuss the potential roles of these targets in improving and preserving renal function
  • Explain the therapeutic implications of these findings

Learning Pathway(s)

  • Diabetes and Metabolism


  • Farsad Afshinnia, MD, MS, FASN
  • Frank C. Brosius, MD


  • The Role of Proximal Tubular Carnitine Acetltransferase in Mitochondrial Nutrient Handling and Energy Homeostasis
    10:00 AM - 10:30 AM
    Krisztian Stadler, PhD 
  • Soluble NogoB Improves DKD by Protecting Vasculature
    10:30 AM - 11:00 AM
    Luigi Gnudi, MD, PhD, FASN 
  • Kruppel-Like Factors and DKD
    11:00 AM - 11:30 AM
    Sandeep K. Mallipattu, MD, FASN 
  • Blockade of the C5a-C5aR1 Axis in DKD
    11:30 AM - 12:00 PM
    Melinda T. Coughlan, PhD