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ASN leads the fight to prevent, treat, and cure kidney diseases throughout the world by educating health professionals and scientists, advancing research and innovation, communicating new knowledge, and advocating for the highest quality care for patients.

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Kidney Week

Basic/Clinical Science Session

CKD-MBD in the Era of Personalized Medicine: Is a New Paradigm Coming? Including the Jack W. Coburn, MD, Endowed Lectureship

October 23, 2020 | 02:30 PM - 04:30 PM

Location: Live-Streamed

Session Description

Renal osteodystrophy (ROD) is a complex disease resulting in increased fractures and mortality. Management should focus on therapy tailored to the underlying bone disease (i.e., ROD-type). However, in most cases, it is not possible to obtain an invasive bone biopsy. This session reviews state-of-the art personalized medicine advancements that may lead to noninvasive approaches for diagnosing, managing, and treating ROD and CKD-associated fractures.

ASN gratefully acknowledges Amgen for support of the Jack W. Coburn, MD, Endowed Lectureship.

Learning Objective(s)

  • Describe the current limitations of noninvasive assessments of bone disease in patients with CKD
  • Discuss novel approaches that may lead to novel diagnostic strategies
  • Explain the importance of bone compartments on ROD pathophysiology
  • Identify practical approaches to diagnosing and managing bone disease in the current era

Learning Pathway(s)

  • Bone and Mineral Metabolism
  • Chronic Kidney Disease


  • Charles Ginsberg, MD
  • Fabrice Mac-Way, MD


  • Rationale for Personalized Medicine Approaches to the Management of CKD-Associated Osteoporosis: The Jack W. Coburn, MD, Endowed Lectureship
    02:30 PM - 03:00 PM
    Glenn Matthew Chertow, MD, MPH, FASN
  • A Personalized, Targeted Approach to Manage Osteoporosis in CKD: A Randomized Clinical Trial Synopsis
    03:00 PM - 03:30 PM
    Hartmut H. Malluche, MD 
  • Single-Cell Methods as a Tool to Redefine Renal Osteodystrophy and Design Future Therapeutics
    03:30 PM - 04:00 PM
    Valentin David, MS, PhD
  • Bone-Tissue Level Gene Expression to Guide Management of Post-Transplant Bone Disease
    04:00 PM - 04:30 PM
    Rosa M.A. Moyses, MD, PhD