CKD-MBD in the Era of Personalized Medicine: Is a New Paradigm Coming? Including the Jack W. Coburn, MD, Endowed Lectureship
October 23, 2020 | 02:30 PM - 04:30 PM
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Basic/Clinical Science Session
CKD-MBD in the Era of Personalized Medicine: Is a New Paradigm Coming? Including the Jack W. Coburn, MD, Endowed Lectureship
October 23, 2020 | 02:30 PM - 04:30 PM
Location: Live-Streamed
Session Description
Renal osteodystrophy (ROD) is a complex disease resulting in increased fractures and mortality. Management should focus on therapy tailored to the underlying bone disease (i.e., ROD-type). However, in most cases, it is not possible to obtain an invasive bone biopsy. This session reviews state-of-the art personalized medicine advancements that may lead to noninvasive approaches for diagnosing, managing, and treating ROD and CKD-associated fractures.
ASN gratefully acknowledges Amgen for support of the Jack W. Coburn, MD, Endowed Lectureship.
Learning Objective(s)
- Describe the current limitations of noninvasive assessments of bone disease in patients with CKD
- Discuss novel approaches that may lead to novel diagnostic strategies
- Explain the importance of bone compartments on ROD pathophysiology
- Identify practical approaches to diagnosing and managing bone disease in the current era
Learning Pathway(s)
- Bone and Mineral Metabolism
- Chronic Kidney Disease
Moderators
- Charles Ginsberg, MD
- Fabrice Mac-Way, MD
Presentations
- Rationale for Personalized Medicine Approaches to the Management of CKD-Associated Osteoporosis: The Jack W. Coburn, MD, Endowed Lectureship
02:30 PM - 03:00 PM
Glenn Matthew Chertow, MD, MPH, FASN
Glenn Matthew Chertow, MD, MPH, FASN
Rationale for Personalized Medicine Approaches to the Management of CKD-Associated Osteoporosis: The Jack W. Coburn, MD, Endowed Lectureship
October 23, 2020 | 02:30 PM - 03:00 PM
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- A Personalized, Targeted Approach to Manage Osteoporosis in CKD: A Randomized Clinical Trial Synopsis
03:00 PM - 03:30 PM
Hartmut H. Malluche, MD
Hartmut H. Malluche, MD
Hartmut H. Malluche, MD, FACP, is the Robert G. Luke Chair in Nephrology, Professor and Chief of the Division of Nephrology, Bone, and Mineral Metabolism at the University of Kentucky in Lexington, Kentucky. Dr. Malluche received his medical degree from J.W. Goethe University in Frankfurt am Main, Germany, and completed a residency and fellowship at the Center for Internal Medicine, University Hospitals, J.W. Goethe University. Prior to his current role, he served as Associate Professor of Medicine in the Department of Internal Medicine, Division of Nephrology, at the University of Southern California Medical Center in Los Angeles. Dr. Malluche has served as a member on numerous scientific advisory councils and clinical research committees and has published more than 400 articles in various scientific journals. He is the editor of the international journal, Clinical Nephrology and the textbook Clinical Nephrology, Dialysis and Transplantation. Dr. Malluche received the Distinguished Lecturer Award from the Chinese Society of Nephrology in 1992 and the Award for Excellence in Research from the University of Kentucky. He is an honorary member of the Australian and New Zealand Society of Nephrology, and he is the founder and Past President of the International Society of Bone Morphometry. His current research interests are in the field of metabolic bone diseases with a focus on renal osteodystrophy and osteoporosis.
A Personalized, Targeted Approach to Manage Osteoporosis in CKD: A Randomized Clinical Trial Synopsis
October 23, 2020 | 03:00 PM - 03:30 PM
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- Single-Cell Methods as a Tool to Redefine Renal Osteodystrophy and Design Future Therapeutics
03:30 PM - 04:00 PM
Valentin David, MS, PhD
Single-Cell Methods as a Tool to Redefine Renal Osteodystrophy and Design Future Therapeutics
October 23, 2020 | 03:30 PM - 04:00 PM
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- Bone-Tissue Level Gene Expression to Guide Management of Post-Transplant Bone Disease
04:00 PM - 04:30 PM
Rosa M.A. Moyses, MD, PhD
Rosa M.A. Moyses, MD, PhD
Dr Rosa M. A. Moysés graduated from the University of São Paulo in Brazil. She specialized in Nephrology at the same service and later started working in the CKD-MBD group of this Institution, position she still occupies.
Her main fields of interest are bone disease, as well as vascular calcification in chronic kidney disease. Her group is one of the most internationally recognized with more than 4,000 bone biopsies performed in CKD patients.
She has several publications in peer review journals of clinical and experimental studies in this field.
Bone-Tissue Level Gene Expression to Guide Management of Post-Transplant Bone Disease
October 23, 2020 | 04:00 PM - 04:30 PM
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