C3 Glomerulopathy and aHUS: From Diagnosis to Transplantation
October 24, 2020 | 10:00 AM - 12:00 PM
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Basic/Clinical Science Session
C3 Glomerulopathy and aHUS: From Diagnosis to Transplantation
October 24, 2020 | 10:00 AM - 12:00 PM
Location: On-Demand
Session Description
C3 glomerulopathies and atypical hemolytic uremic syndrome (aHUS) comprise different disease entities that are (almost always) caused by dysregulated complement. This session reviews the spectrum of these diseases from initial diagnosis to post-transplant management. We discuss the etiologic and histologic characteristics of C3 glomerulopathies and aHUS, as well as approaches to diagnosing underlying complement abnormalities and applying that information in patient management.
Learning Objective(s)
- Explain the different etiologies and histopathologic manifestations of C3 glomerulopathies and aHUS
- Identify the components of the complement pathway and how they can be evaluated in C3 glomerulopathy and aHUS
- Describe the process of consolidating diagnostic and prognostic information to manage patients awaiting kidney transplantation
- Interpret the rationale and the options of immunosuppressive and complement-targeted therapies, including those for kidney transplant recipients
Learning Pathway(s)
- Glomerular Diseases
- Transplantation/Immunology
Moderators
- Kerstin U. Amann, MD
- Vineeta Kumar, MD
Presentations
- The Histopathologic Spectrum of C3 Glomerulopathies and aHUS
10:00 AM - 10:30 AM
Vivette D. D'Agati, MD
The Histopathologic Spectrum of C3 Glomerulopathies and aHUS
October 24, 2020 | 10:00 AM - 10:30 AM
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- Complement Abnormalities and Rational Diagnostic in C3 Glomerulopathy and aHUS
10:30 AM - 11:00 AM
Neil S. Sheerin, MBBS, PhD
Neil S. Sheerin, MBBS, PhD
Complement Abnormalities and Rational Diagnostic in C3 Glomerulopathy and aHUS
October 24, 2020 | 10:30 AM - 11:00 AM
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- How to Inhibit Complement in Patients With C3 Glomerulopathy aHUS
11:00 AM - 11:30 AM
Peter F. Zipfel, PhD
How to Inhibit Complement in Patients With C3 Glomerulopathy aHUS
October 24, 2020 | 11:00 AM - 11:30 AM
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- Treating Patients with C3 Glomerulopathy and aHUS, Including the Kidney Transplant Candidate
11:30 AM - 12:00 PM
Carla Marie Nester, MD, MS, FASN
Carla Marie Nester, MD, MS, FASN
Dr. Nester is the Jean E. Robillard, MD Chair and Director of the Division of Pediatric Nephrology, Dialysis and Transplantation - Stead Family Children's Hospital, Iowa, USA. In addition, she is the Associate Director of the Clinical and Research Laboratory, Molecular Otolaryngology and Renal Research Laboratory.
Dr. Nester is an Associate Professor in the Department of Internal Medicine and the Department of Pediatrics at the University of Iowa.
Treating Patients with C3 Glomerulopathy and aHUS, Including the Kidney Transplant Candidate
October 24, 2020 | 11:30 AM - 12:00 PM
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