ASN's Mission

ASN leads the fight to prevent, treat, and cure kidney diseases throughout the world by educating health professionals and scientists, advancing research and innovation, communicating new knowledge, and advocating for the highest quality care for patients.

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Kidney Week

Basic/Clinical Science Session

Organelle Function and Dysfunction in Kidney Diseases

October 24, 2020 | 10:00 AM - 12:00 PM

Location: On-Demand

Session Description

Recent technological advances have revealed critical roles for varied intracellular organelles in the pathogenesis of kidney diseases. In addition, organelles can cross-talk, adding a layer of complexity to organelle regulation. Understanding dynamic organelle signaling can help us better understand pathologies of renal disease and can also lead to novel therapies.

Learning Objective(s)

  • Describe the in-depth organelle biology in the kidney
  • Explain how organelle cross-talk can influence cell function
  • Discuss novel therapeutics that target the endoplasmic reticulum

Learning Pathway(s)

  • Cell and Transport Physiology


  • Uta Erdbruegger, MD
  • Jennie Lin, MD, MS


  • Developing Novel Endoplasmic Reticulum-Targeted Treatment for Kidney Diseases
    10:00 AM - 10:30 AM
    Ying Maggie Chen, MD, PhD, FASN 
  • Endoplasmic Reticulum-Associated Degradation Component SEL1L in Nephrotic Syndrome
    10:30 AM - 11:00 AM
    Ling Qi, PhD 
  • Organelle Cross-Talk and Tubular Inflammation
    11:00 AM - 11:30 AM
    Reiko Inagi, PhD 
  • Polycystic and Tubulointerstitial Phenotypes of ER Genes in the Kidney
    11:30 AM - 12:00 PM
    Whitney Besse, MD