ASN's Mission

ASN leads the fight to prevent, treat, and cure kidney diseases throughout the world by educating health professionals and scientists, advancing research and innovation, communicating new knowledge, and advocating for the highest quality care for patients.

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1401 H St, NW, Ste 900, Washington, DC 20005

email@asn-online.org

202-640-4660

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Kidney Week

Basic/Clinical Science Session

It's All About the Collagen

November 07, 2021 | 10:00 AM - 12:00 PM

Location: Live-Stream, Virtual Only

Session Description

The development of genetically characterized databases (e.g., UK Biobank) have heralded a new type of epidemiologic study, where gene variants can be correlated with phenotypic data in the general population. Interestingly, genome-wide association studies (GWAS) of kidney-relevant phenotypes have implicated collagen in the pathogenesis of many kidney diseases. This session explores the latest research in this area.

Learning Objective(s)

  • Describe the results of recent GWAS studies
  • Describe the biology of type IV collagen
  • Outline the complexities of the kidney matrisome through proteomic studies

Learning Pathway(s)

  • Glomerular Diseases
  • Genetic Diseases of the Kidneys

Moderators

  • Anna Kottgen, MD, MPH
  • Jeffrey H. Miner, PhD, FASN

Presentations

  • Human Genetic Studies Point to an Emerging Role for Type IV Collagen in CKD
    10:00 AM - 10:30 AM
    Moumita Barua, MD
  • Proteomics Reveal the Complexity of Basement Membranes
    10:30 AM - 11:00 AM
    Rachel Lennon, MBBS, PhD
  • In Vitro Modeling of Basement Membrane Disorders
    11:00 AM - 11:30 AM
    Stefano Da Sacco, PhD
  • Genomics of Diabetic Kidney Disease Reveal an Important Role for Collagen
    11:30 AM - 12:00 PM
    Jose C. Florez, MD, PhD