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ASN leads the fight to prevent, treat, and cure kidney diseases throughout the world by educating health professionals and scientists, advancing research and innovation, communicating new knowledge, and advocating for the highest quality care for patients.

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Kidney Week

Basic/Clinical Science Session

Metabolic (In)competence in AKI

November 06, 2021 | 10:00 AM - 12:00 PM

Location: On-Demand, Virtual Only

Session Description

Dysregulation of energy metabolism is emerging as a key driver in the pathogenesis of AKI. This session discusses the role of metabolic pathways and metabolites in AKI outcomes.

Learning Objective(s)

  • Describe the role of metabolic alterations in regulating production of fibroblast growth factor 23 during AKI
  • Discuss how impaired renal gluconeogenesis during AKI alters systemic metabolism and dictates AKI-associated mortality
  • Discuss the prognostic potential of alterations in adenosine triphosphate dynamics during AKI.
  • Explain how metabolites released from apoptotic cells can modulate the tissue microenvironment

Learning Pathway(s)

  • Acute Kidney Injury


  • Amandeep Bajwa, PhD
  • Samir M. Parikh, MD, FASN


  • Fibroblast Growth Factor 23 in AKI
    10:00 AM - 12:00 PM
    Eugene P. Rhee, MD
  • Altered Glucose Metabolism in AKI
    10:00 AM - 12:00 PM
    Sophie M. De Seigneux, MD, PhD
  • Spatiotemporal Adenosine Triphosphate Dynamics in AKI
    10:00 AM - 12:00 PM
    Motoko Yanagita, MD, PhD
  • Metabolic Signals from Apoptotic Cells in Inflammation
    10:00 AM - 12:00 PM
    Kodi S. Ravichandran, PhD