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ASN leads the fight to prevent, treat, and cure kidney diseases throughout the world by educating health professionals and scientists, advancing research and innovation, communicating new knowledge, and advocating for the highest quality care for patients.

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Kidney Week

Educational Symposium

Basics to Bedside: State-of-the-Art Rationale and Approach to Hyperkalemia in Kidney Diseases

November 05, 2021 | 12:45 PM - 01:45 PM

Location: Simulive, Virtual Only

Session Description

A fundamental role of the kidneys, potassium regulation is commonly dysfunctional in the setting of kidney diseases. Alterations in potassium metabolism are even more common in older populations with multiple comorbidities who are treated with such medications as RAAS inhibitors. Hyperkalemia specifically is associated with a higher risk of death and cardiovascular complications. Prevention and management of severe hyperkalemia remains a core responsibility of nephrologists in reducing the risk for cardiac arrhythmias and other complications.

Reviewing the fundamentals of potassium regulation is important to all providers of nephrology care. This symposium discusses cellular and transport basics in relation to the development of hyperkalemia therapies, including novel potassium binders. Emerging evidence from clinical trials is outlined for use in making effective treatment decisions and understanding the spectrum of safety considerations.

Support is provided by an educational grant from Vifor Pharma, Inc.

Learning Objective(s)

  • Describe the current burden, severity, and associated health conditions of hyperkalemia in diverse patient populations
  • Discuss the pathophysiology of hyperkalemia in kidney diseases and how it informs novel approaches to treatment

Learning Pathway(s)

  • Hypertension and CVD
  • Bone and Mineral Metabolism


  • Melanie P. Hoenig, MD


  • Introduction
    12:45 PM - 12:55 PM
    Melanie P. Hoenig, MD
  • Potassium Dysregulation Among Diverse Patient Populations with Kidney Diseases
    12:55 PM - 01:20 PM
    Sankar D. Navaneethan, MD, MS, MPH, FASN
  • The Physiology of Hyperkalemia and Its Treatments
    01:20 PM - 01:45 PM
    Catherine M. Clase, MBChB, FASN