Basic/Clinical Science Session
Hypertension Is an Immune-Mediated Disease
November 04, 2022 | 10:30 AM - 12:30 PM
Location: W311, Orange County Convention Center, West Building
Session Description
Hypertension is a major contributor to target organ damage with excess morbidity and mortality. This session examines the role of the immune system in the pathogenesis of hypertension. Particular emphasis is given to the role monocyte activation plays in the setting of excess dietary salt-induced BP elevation. Inhibition of monocytes is explored as a novel approach to the treatment of hypertension. This session also covers the role of an octameric protein complex involved in Bardet-Biedl syndrome (BBSome) in the pathogenesis of hypertension.
Learning Objective(s)
- Define the role of the immune system in contributing to the development of systemic hypertension
- Discuss the role of monocytes as novel therapeutic targets in the treatment of hypertension
- Describe the effects of minocycline as a treatment for resistant hypertension
Learning Pathway(s)
- Hypertension and Cardiorenal Disorders
Moderators
- Susan B. Gurley, MD, PhD
- Jennifer L. Pluznick, PhD
Presentations
- Is Hypertension an Immune Disease?
10:30 AM - 11:00 AM
David G. Harrison, MD
- Monocytes as Immune Targets in Arterial Hypertension
11:00 AM - 11:30 AM
Philip Wenzel, MD
- Minocycline as a Treatment of Resistant Hypertension: Results of a Clinical Study
11:30 AM - 12:00 PM
Eileen M. Handberg, PhD, APRN, RN
- Role of Immune Cells in Hypertension
12:00 PM - 12:30 PM
Ernesto L. Schiffrin, MD, PhD
