Translational Session
Molecular Mechanisms of Hypertension and Cardiovascular Effects
November 06, 2022 | 09:30 AM - 11:30 AM
Location: W308, Orange County Convention Center, West Building
Session Description
This session provides information on some of the latest breakthroughs in our understanding of the roles of bile acids, angiogenic factors, and circadian rhythm in the regulation of BP. In addition, presenters discuss some of the pathogenic links between elevated BP and CKD as revealed using human and animal genomic studies.
Learning Objective(s)
- Examine the effect of the nonangiogenic, maternally sequestered protein ELP-VEGF B as a potential therapeutic for preeclampsia
- Discuss adverse cardiorenal outcomes and increased risk of cardiovascular mortality associated with dysregulation of the circadian rhythm of BP
- Describe the association of impaired bile acid signaling with dietary salt-induced elevations in BP
Learning Pathway(s)
- Hypertension and Cardiorenal Disorders
Moderators
- Bryan Becker, PhD
- Mahboob Rahman, MBBS, MD
Presentations
- Elastin-Like Polypeptide: VEGF-B Fusion Protein for Treatment of Preeclampsia
09:30 AM - 10:00 AM
Gene L. Bidwell, PhD
- Dysregulation of the Circadian Rhythm of BP Is Associated with Adverse Cardiorenal Outcomes
10:00 AM - 10:30 AM
Michelle L. Gumz, PhD
- CKD Pathogenesis in Hypertension from Human and Animal Genomic Studies
10:30 AM - 11:00 AM
- Salt-Induced BP Elevation Is Associated with Impaired Bile Acid Signaling and Monocyte Activation
11:00 AM - 11:30 AM
Jeanne A. Ishimwe, PhD
