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To create a world without kidney diseases, the ASN Alliance for Kidney Health elevates care by educating and informing, driving breakthroughs and innovation, and advocating for policies that create transformative changes in kidney medicine throughout the world.

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Kidney Week

Basic/Clinical Science Session

Impact of MicroRNAs and Circular RNAs on the Pathogenesis and Prognosis of Glomerular Diseases

November 03, 2022 | 04:30 PM - 06:00 PM

Location: W304, Orange County Convention Center, West Building

Session Description

MicroRNAs (miRNAs) and circular RNAs (circRNAs) are noncoding RNA molecules that are present in many human cell types and have potential as regulators of gene expression, particularly miRNAs that can pair with and silence messenger RNAs. This session discusses these noncoding RNAs and their involvement in a variety of human diseases. In recent years, specific noncoding RNAs have been shown to have a role in the development and progression of a number of kidney diseases.

Support is provided by an educational grant from Travere Therapeutics, Inc.

Learning Objective(s)

  • Understand how these noncoding RNAs can act to regulate the expression of genes involved in kidney function and immune regulation
  • Identify miRNAs that are up- or down-regulated in different cell types in specific glomerular diseases
  • Describe how expression of certain miRNAs in kidney tissue may be useful in predicting disease progression and how identification of urinary levels of specific noncoding RNAs may be useful in monitoring disease activity

Learning Pathway(s)

  • Pathology
  • Glomerular Diseases

Moderators

  • Vineet Gupta, PhD
  • Francesco Paolo Schena, MD, FASN

Presentations

  • MicroRNAs in Membranous Nephropathy and FSGS
    04:30 PM - 04:50 PM
    Mario Schiffer, MD, MBA
  • MicroRNAs in IgA Nephropathy
    04:50 PM - 05:10 PM
    Izabella Z.A. Pawluczyk, PhD
  • MicroRNAs in Diabetic Nephropathy
    05:10 PM - 05:30 PM
    Maurice B. Fluitt, PhD
  • Circular RNAs and MicroRNAs in Lupus Nephritis
    05:30 PM - 05:50 PM
    Jeffrey B. Kopp, MD, FASN
  • Q&A
    05:50 PM - 06:00 PM