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To create a world without kidney diseases, the ASN Alliance for Kidney Health elevates care by educating and informing, driving breakthroughs and innovation, and advocating for policies that create transformative changes in kidney medicine throughout the world.

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Kidney Week

Basic/Clinical Science Session

Role of Basolateral Potassium Channel in Potassium Homeostasis and Diseases

November 05, 2022 | 10:30 AM - 12:30 PM

Location: W230, Orange County Convention Center‚ West Building

Session Description

Basolateral potassium channels in nephrons have an important role in kidney potassium and sodium handling. Mutations in these potassium channels result in significant electrolyte disorders and affect hemodynamic state. This session discusses the roles of kidney basolateral potassium channels in salt wasting disorder and kidney sodium handling. Presentations explore the mechanisms underlying the roles of these potassium channels as well as potential therapeutic agents that target them.

Learning Objective(s)

  • Define potassium homeostasis
  • Describe the electrolyte disorders caused by mutations in these potassium channels
  • Discuss the mechanisms underlying the roles of basolateral potassium channels in electrolyte disorder and kidney and cardiovascular diseases
  • Explore the potential utility of potassium channel inhibitors

Learning Pathway(s)

  • Fluid‚ Electrolyte‚ and Acid-Base Disorders
  • Kidney Biology and Physiology


  • Chou-Long Huang, MD, PhD
  • Janet D. Klein, PhD