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To create a world without kidney diseases, the ASN Alliance for Kidney Health elevates care by educating and informing, driving breakthroughs and innovation, and advocating for policies that create transformative changes in kidney medicine throughout the world.

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Kidney Week

Basic/Clinical Science Session

Metabolism and Kidney Diseases

November 03, 2022 | 02:00 PM - 04:00 PM

Location: W230, Orange County Convention Center, West Building

Session Description

Metabolism consists of a series of reactions that occur within living cells. The process of metabolism involves many cellular pathways to ultimately provide cells with the energy required to carry out their function. In eukaryotes, the metabolic pathways occur within the cytosol and mitochondria of cells with the utilization of glucose or fatty acids providing the majority of cellular energy. The changes of these metabolic pathways due to alteration of transporting glucoses in the cells or alteration of signal transduction affecting these pathways will cause metabolic disturbances, ultimately leading to development of diseases. This session provides an overview of metabolism and mitochondria function, imbalances of metabolism, and metabolic reprogramming, as well as their roles in development of kidney diseases and hypertension.

Learning Objective(s)

  • Describe the metabolism, cellular pathways, and function of mitochondria
  • Explain the risks of imbalanced metabolism in development of kidney disease and hypertension
  • Discuss the potential mechanisms underlying the roles of metabolic imbalances and metabolic reprogramming in the development of kidney diseases and hypertension

Learning Pathway(s)

  • Fluid, Electrolyte, and Acid-Base Disorders
  • Hypertension and Cardiorenal Disorders


  • Jeanie Park, MD, MS
  • Sian Piret, PhD


  • Metabolic Decision in Development and Disease: Overview in Kidney Perspective
    02:00 PM - 02:30 PM
    Scott Summers, PhD
  • Renal Metabolism and Hypertension
    02:30 PM - 03:00 PM
    Mingyu Liang, MD, PhD
  • Fructose Metabolism in Kidney Diseases
    03:00 PM - 03:30 PM
    Miguel A. Lanaspa, PhD, DVM
  • Metabolic Reprogramming in PKD
    03:30 PM - 04:00 PM
    Alessandra Boletta, PhD