- Uric Acid Crystal Deposition Triggers Tubule Dilation in Normal Kidneys and Cystogenesis in Polycystic Kidney Disease (PKD)
10:00 AM - 12:00 PM
Uric Acid Crystal Deposition Triggers Tubule Dilation in Normal Kidneys and Cystogenesis in Polycystic Kidney Disease (PKD)
November 04, 2022 | 10:00 AM - 12:00 PM
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- Ferritin as an Inflammatory Molecule in Autosomal Dominant Polycystic Kidney Disease
10:00 AM - 12:00 PM
Ferritin as an Inflammatory Molecule in Autosomal Dominant Polycystic Kidney Disease
November 04, 2022 | 10:00 AM - 12:00 PM
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- Divergent Injury Effects of Cisplatin Treatment on Promoting Cyst Formation in Adult Pkd2 Mutant Mouse Model
10:00 AM - 12:00 PM
Divergent Injury Effects of Cisplatin Treatment on Promoting Cyst Formation in Adult Pkd2 Mutant Mouse Model
November 04, 2022 | 10:00 AM - 12:00 PM
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- CD206+ Resident Macrophages: A Candidate Biomarker for Renal Cystic Disease Activity in Preclinical Models and Patients With Autosomal Dominant Polycystic Kidney Disease
10:00 AM - 12:00 PM
CD206+ Resident Macrophages: A Candidate Biomarker for Renal Cystic Disease Activity in Preclinical Models and Patients With Autosomal Dominant Polycystic Kidney Disease
November 04, 2022 | 10:00 AM - 12:00 PM
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- Automated Detection and Quantification of Individual Collagen Fibers in a Mouse Model of Polycystic Kidney Disease
10:00 AM - 12:00 PM
Automated Detection and Quantification of Individual Collagen Fibers in a Mouse Model of Polycystic Kidney Disease
November 04, 2022 | 10:00 AM - 12:00 PM
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- High-Fat Feeding in Pkd1 RC/RC Mice Associates With Upregulation of Havcr1 and Immune Activation
10:00 AM - 12:00 PM
High-Fat Feeding in Pkd1 RC/RC Mice Associates With Upregulation of Havcr1 and Immune Activation
November 04, 2022 | 10:00 AM - 12:00 PM
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- Refining the Developmental Window That Determines Different Kinetics of Cystogenesis After Pkd2 Inactivation in Mice
10:00 AM - 12:00 PM
Refining the Developmental Window That Determines Different Kinetics of Cystogenesis After Pkd2 Inactivation in Mice
November 04, 2022 | 10:00 AM - 12:00 PM
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- Raising Serum Uric Acid With a Uricase Inhibitor Worsens Polycystic Kidney Disease in Rat and Mouse Models
10:00 AM - 12:00 PM
Raising Serum Uric Acid With a Uricase Inhibitor Worsens Polycystic Kidney Disease in Rat and Mouse Models
November 04, 2022 | 10:00 AM - 12:00 PM
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- Turning the Kidney Into a Lymphoid Organ
10:00 AM - 12:00 PM
Turning the Kidney Into a Lymphoid Organ
November 04, 2022 | 10:00 AM - 12:00 PM
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- Unbiased RNA-Sequencing Analysis of PKD2-/- Proximal Tubular Epithelial Cells Reveals Stabilization of Primary Cilia by Polycystin-2
10:00 AM - 12:00 PM
Unbiased RNA-Sequencing Analysis of PKD2-/- Proximal Tubular Epithelial Cells Reveals Stabilization of Primary Cilia by Polycystin-2
November 04, 2022 | 10:00 AM - 12:00 PM
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- Tracking Polycystin2 In Vivo Using a Novel Engineered Pkd2-HALO Allele
10:00 AM - 12:00 PM
Tracking Polycystin2 In Vivo Using a Novel Engineered Pkd2-HALO Allele
November 04, 2022 | 10:00 AM - 12:00 PM
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- Active BRAF Inhibits LKB1-AMPK Signaling and Acetyl-CoA Carboxylase Phosphorylation and Increases Renal Fibrosis in a Model of Polycystic Kidney Disease
10:00 AM - 12:00 PM
Active BRAF Inhibits LKB1-AMPK Signaling and Acetyl-CoA Carboxylase Phosphorylation and Increases Renal Fibrosis in a Model of Polycystic Kidney Disease
November 04, 2022 | 10:00 AM - 12:00 PM
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- Comparative Transcriptomics of PKD1 Downregulation and PKA Upregulation or Downregulation
10:00 AM - 12:00 PM
Comparative Transcriptomics of PKD1 Downregulation and PKA Upregulation or Downregulation
November 04, 2022 | 10:00 AM - 12:00 PM
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- Loss of Cross-Talk Between Polycystin 1 and LSD1 Promotes Cyst Growth Through Interaction With Ataxia Telangiectasia Mutated and Phase Separation Mechanism in Autosomal Dominant Polycystic Kidney Disease
10:00 AM - 12:00 PM
Loss of Cross-Talk Between Polycystin 1 and LSD1 Promotes Cyst Growth Through Interaction With Ataxia Telangiectasia Mutated and Phase Separation Mechanism in Autosomal Dominant Polycystic Kidney Disease
November 04, 2022 | 10:00 AM - 12:00 PM
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- Single Gene Mutations in Pkd1 or Tsc2 Alter Extracellular Vesicles Production and Trafficking
10:00 AM - 12:00 PM
Single Gene Mutations in Pkd1 or Tsc2 Alter Extracellular Vesicles Production and Trafficking
November 04, 2022 | 10:00 AM - 12:00 PM
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- Generation of Mice Expressing an N-Terminal SNAP-Tagged Pkd1 Allele
10:00 AM - 12:00 PM
Generation of Mice Expressing an N-Terminal SNAP-Tagged Pkd1 Allele
November 04, 2022 | 10:00 AM - 12:00 PM
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- Autophagy Is Dynamically Dysregulated Along the Pathogenesis of Autosomal Dominant Polycystic Kidney Disease
10:00 AM - 12:00 PM
Autophagy Is Dynamically Dysregulated Along the Pathogenesis of Autosomal Dominant Polycystic Kidney Disease
November 04, 2022 | 10:00 AM - 12:00 PM
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- Assessing the Therapeutic Potential of Readthrough of Nonsense Mutations in Autosomal Dominant Polycystic Kidney Disease (ADPKD)
10:00 AM - 12:00 PM
Assessing the Therapeutic Potential of Readthrough of Nonsense Mutations in Autosomal Dominant Polycystic Kidney Disease (ADPKD)
November 04, 2022 | 10:00 AM - 12:00 PM
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- Longitudinal Characterization of Mitochondrial and Metabolic Changes in Autosomal Dominant Polycystic Kidney Disease
10:00 AM - 12:00 PM
Longitudinal Characterization of Mitochondrial and Metabolic Changes in Autosomal Dominant Polycystic Kidney Disease
November 04, 2022 | 10:00 AM - 12:00 PM
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- Loss of Intestinal Pkd1 Does Not Alter Epithelial Cell Integrity or Inflammation in Early Autosomal Dominant Polycystic Kidney Disease
10:00 AM - 12:00 PM
Loss of Intestinal Pkd1 Does Not Alter Epithelial Cell Integrity or Inflammation in Early Autosomal Dominant Polycystic Kidney Disease
November 04, 2022 | 10:00 AM - 12:00 PM
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- CD74 Promotes Cyst Growth and Interstitial Fibrosis in Autosomal Dominant Polycystic Kidney Disease
10:00 AM - 12:00 PM
CD74 Promotes Cyst Growth and Interstitial Fibrosis in Autosomal Dominant Polycystic Kidney Disease
November 04, 2022 | 10:00 AM - 12:00 PM
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- Role of GREMLIN in Autosomal Dominant Polycystic Kidney Disease (ADPKD)
10:00 AM - 12:00 PM
Role of GREMLIN in Autosomal Dominant Polycystic Kidney Disease (ADPKD)
November 04, 2022 | 10:00 AM - 12:00 PM
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- Ouabain Treatment Increases Cyst Progression in a Slowly Progressive Autosomal Dominant Polycystic Kidney Disease Mouse Model
10:00 AM - 12:00 PM
Ouabain Treatment Increases Cyst Progression in a Slowly Progressive Autosomal Dominant Polycystic Kidney Disease Mouse Model
November 04, 2022 | 10:00 AM - 12:00 PM
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- Electrophysiological Characterization of Polycystin-2 Mutants With Disease-Associated Missense Mutations in the Channel's Pore Loop
10:00 AM - 12:00 PM
Electrophysiological Characterization of Polycystin-2 Mutants With Disease-Associated Missense Mutations in the Channel's Pore Loop
November 04, 2022 | 10:00 AM - 12:00 PM
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- Lipophilic Methanethiosulfonate (MTS) Reagents Inhibit Ion Channel Function of Polycystin-2 With a Gain-of-Function Mutation (F604P)
10:00 AM - 12:00 PM
Lipophilic Methanethiosulfonate (MTS) Reagents Inhibit Ion Channel Function of Polycystin-2 With a Gain-of-Function Mutation (F604P)
November 04, 2022 | 10:00 AM - 12:00 PM
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- SMYD3 Regulates Cyst Growth and Ciliogenesis in Autosomal Dominant Polycystic Kidney Disease
10:00 AM - 12:00 PM
SMYD3 Regulates Cyst Growth and Ciliogenesis in Autosomal Dominant Polycystic Kidney Disease
November 04, 2022 | 10:00 AM - 12:00 PM
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- The Polycystin-1 C-Terminal Tail (CTT) Suppresses Cystic Disease: Elucidating the Underlying Mechanisms
10:00 AM - 12:00 PM
The Polycystin-1 C-Terminal Tail (CTT) Suppresses Cystic Disease: Elucidating the Underlying Mechanisms
November 04, 2022 | 10:00 AM - 12:00 PM
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- Deep Learning Allows Automated Analysis of Cystogenesis in Novel Xenopus Animal Models for Autosomal Polycystic Kidney Disease
10:00 AM - 12:00 PM
Deep Learning Allows Automated Analysis of Cystogenesis in Novel Xenopus Animal Models for Autosomal Polycystic Kidney Disease
November 04, 2022 | 10:00 AM - 12:00 PM
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- The Transcriptional Regulator AP-2α Maintains the Tubular Diameter of Renal Collecting Ducts in Adult Mice
10:00 AM - 12:00 PM
The Transcriptional Regulator AP-2α Maintains the Tubular Diameter of Renal Collecting Ducts in Adult Mice
November 04, 2022 | 10:00 AM - 12:00 PM
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- CDK7-CDK6-FIP5 Phosphorylation Cascade Controls Axoneme Polyglutamylation and Polycystin Signaling in Primary Cilia
10:00 AM - 12:00 PM
CDK7-CDK6-FIP5 Phosphorylation Cascade Controls Axoneme Polyglutamylation and Polycystin Signaling in Primary Cilia
November 04, 2022 | 10:00 AM - 12:00 PM
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- Role of CFTR in Autosomal Dominant Polycystic Kidney Disease
10:00 AM - 12:00 PM
Role of CFTR in Autosomal Dominant Polycystic Kidney Disease
November 04, 2022 | 10:00 AM - 12:00 PM
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- A Quantitative Proteomic Study of Tolvaptan Treatment in an Orthologous Mouse Model of Autosomal Dominant Polycystic Kidney Disease: What Remains Altered?
10:00 AM - 12:00 PM
A Quantitative Proteomic Study of Tolvaptan Treatment in an Orthologous Mouse Model of Autosomal Dominant Polycystic Kidney Disease: What Remains Altered?
November 04, 2022 | 10:00 AM - 12:00 PM
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- Protein 4.1O Binds to Polycystin-1, Activates Ubiquitination, and Inhibits Polycystin-1 Signaling
10:00 AM - 12:00 PM
Protein 4.1O Binds to Polycystin-1, Activates Ubiquitination, and Inhibits Polycystin-1 Signaling
November 04, 2022 | 10:00 AM - 12:00 PM
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- Effect of Enalapril in a Novel Human Orthologous Rat Model of Autosomal Recessive Polycystic Kidney Disease With Salt-Sensitive Hypertension
10:00 AM - 12:00 PM
Effect of Enalapril in a Novel Human Orthologous Rat Model of Autosomal Recessive Polycystic Kidney Disease With Salt-Sensitive Hypertension
November 04, 2022 | 10:00 AM - 12:00 PM
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- Cilk1 Deficiency Induces Cyst Formation and Abnormal Ciliary Trafficking via Klc3
10:00 AM - 12:00 PM
Cilk1 Deficiency Induces Cyst Formation and Abnormal Ciliary Trafficking via Klc3
November 04, 2022 | 10:00 AM - 12:00 PM
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- Ion and Metabolite Composition of Cystic Fluid From a Rat Model of Autosomal Recessive Polycystic Kidney Disease (ARPKD)
10:00 AM - 12:00 PM
Ion and Metabolite Composition of Cystic Fluid From a Rat Model of Autosomal Recessive Polycystic Kidney Disease (ARPKD)
November 04, 2022 | 10:00 AM - 12:00 PM
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- Disruption of Cystin Myristoylation Causes Autosomal Recessive Polycystic Kidney Disease (ARPKD)
10:00 AM - 12:00 PM
Disruption of Cystin Myristoylation Causes Autosomal Recessive Polycystic Kidney Disease (ARPKD)
November 04, 2022 | 10:00 AM - 12:00 PM
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- Cardiac Hypertrophy in Rodents With Polycystic Kidney Disease (PKD) Before the Onset of Hypertension
10:00 AM - 12:00 PM
Cardiac Hypertrophy in Rodents With Polycystic Kidney Disease (PKD) Before the Onset of Hypertension
November 04, 2022 | 10:00 AM - 12:00 PM
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- Metformin Worsens Kidney Function and Has No Effect on Cyst Growth in the PCK Rat Model of Autosomal Recessive Polycystic Kidney Disease (ARPKD)
10:00 AM - 12:00 PM
Metformin Worsens Kidney Function and Has No Effect on Cyst Growth in the PCK Rat Model of Autosomal Recessive Polycystic Kidney Disease (ARPKD)
November 04, 2022 | 10:00 AM - 12:00 PM
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- Cleavage of Pkhd1 Results in a Small Fragment That Localizes and Functions Within Mitochondria
10:00 AM - 12:00 PM
Cleavage of Pkhd1 Results in a Small Fragment That Localizes and Functions Within Mitochondria
November 04, 2022 | 10:00 AM - 12:00 PM
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- Mice With a Genomic Deletion of Pkhd1 Exons 3-67 Have Minimal Renal Manifestations but Evidence of Transcriptional Network Changes by snRNA Sequencing
10:00 AM - 12:00 PM
Mice With a Genomic Deletion of Pkhd1 Exons 3-67 Have Minimal Renal Manifestations but Evidence of Transcriptional Network Changes by snRNA Sequencing
November 04, 2022 | 10:00 AM - 12:00 PM
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- Conserved Glycine Rich (G8) Domains in Zebrafish Fibrocystin-L (FPC-L) Paralogs Identify a Tractable Experimental System for Functional Studies of PKHD1-Encoded FPC
10:00 AM - 12:00 PM
Conserved Glycine Rich (G8) Domains in Zebrafish Fibrocystin-L (FPC-L) Paralogs Identify a Tractable Experimental System for Functional Studies of PKHD1-Encoded FPC
November 04, 2022 | 10:00 AM - 12:00 PM
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- Pathogenic STAT3 Activation in Cystic Kidney and Bile Duct Epithelia of Murine Pkhd1-Knockout
10:00 AM - 12:00 PM
Pathogenic STAT3 Activation in Cystic Kidney and Bile Duct Epithelia of Murine Pkhd1-Knockout
November 04, 2022 | 10:00 AM - 12:00 PM
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- Polycystins Are Required for Renal Tubulointerstitial Fibrosis
10:00 AM - 12:00 PM
Polycystins Are Required for Renal Tubulointerstitial Fibrosis
November 04, 2022 | 10:00 AM - 12:00 PM
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- Injury-Induced Renal Fibrosis Promotes Cystogenesis and Cyst Growth in Adult Mice With Autosomal Dominant Polycystic Kidney Disease
10:00 AM - 12:00 PM
Injury-Induced Renal Fibrosis Promotes Cystogenesis and Cyst Growth in Adult Mice With Autosomal Dominant Polycystic Kidney Disease
November 04, 2022 | 10:00 AM - 12:00 PM
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- Role of Glutamine Transporter Snat3 in Promoting Polycystic Kidney Disease
10:00 AM - 12:00 PM
Role of Glutamine Transporter Snat3 in Promoting Polycystic Kidney Disease
November 04, 2022 | 10:00 AM - 12:00 PM
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- The Renal Circadian Clock Is Disrupted in Autosomal Polycystic Kidney Disease
10:00 AM - 12:00 PM
The Renal Circadian Clock Is Disrupted in Autosomal Polycystic Kidney Disease
November 04, 2022 | 10:00 AM - 12:00 PM
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- Mechanisms of Cystogenesis by Cd79a-Driven, Conditional mTOR Activation in Mouse Developing Nephron
10:00 AM - 12:00 PM
Mechanisms of Cystogenesis by Cd79a-Driven, Conditional mTOR Activation in Mouse Developing Nephron
November 04, 2022 | 10:00 AM - 12:00 PM
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- Combined Transcriptome and Metabolome Profiling in a Mouse Model of Tuberous Sclerosis Complex Renal Cystic Disease
10:00 AM - 12:00 PM
Combined Transcriptome and Metabolome Profiling in a Mouse Model of Tuberous Sclerosis Complex Renal Cystic Disease
November 04, 2022 | 10:00 AM - 12:00 PM
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- The Endocannabinoid System Mediates Cystogenesis in Tuberous Sclerosis Kidney Disease
10:00 AM - 12:00 PM
The Endocannabinoid System Mediates Cystogenesis in Tuberous Sclerosis Kidney Disease
November 04, 2022 | 10:00 AM - 12:00 PM
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- Planar Cell Polarity Effector Fuzzy in Actin Regulation and Ciliogenesis
10:00 AM - 12:00 PM
Planar Cell Polarity Effector Fuzzy in Actin Regulation and Ciliogenesis
November 04, 2022 | 10:00 AM - 12:00 PM
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- The Ciliary Phosphoinositide Pathway Regulates the Level of Polycystins in Cilia
10:00 AM - 12:00 PM
The Ciliary Phosphoinositide Pathway Regulates the Level of Polycystins in Cilia
November 04, 2022 | 10:00 AM - 12:00 PM
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- Early Cyst Formation Leads to the Development of an Inflammatory Microenvironment and Tissue Remodeling in Polycystic Kidney Disease
10:00 AM - 12:00 PM
Early Cyst Formation Leads to the Development of an Inflammatory Microenvironment and Tissue Remodeling in Polycystic Kidney Disease
November 04, 2022 | 10:00 AM - 12:00 PM
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- Time-Restricted Feeding Outperforms Periodic Fasting Head-to-Head in Slowing and Reversing Progression of Polycystic Kidney Disease in the Han:SPRD Rat Model
10:00 AM - 12:00 PM
Time-Restricted Feeding Outperforms Periodic Fasting Head-to-Head in Slowing and Reversing Progression of Polycystic Kidney Disease in the Han:SPRD Rat Model
November 04, 2022 | 10:00 AM - 12:00 PM
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- Changes in Tubule Flow During Renal Cyst Development
10:00 AM - 12:00 PM
Changes in Tubule Flow During Renal Cyst Development
November 04, 2022 | 10:00 AM - 12:00 PM
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- Polycystin-2 Like 1 in Renal Cyst Formation
10:00 AM - 12:00 PM
Polycystin-2 Like 1 in Renal Cyst Formation
November 04, 2022 | 10:00 AM - 12:00 PM
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- A scRNAseq Approach to Define Early Events in Cyst Formation and Stepwise Transformation
10:00 AM - 12:00 PM
A scRNAseq Approach to Define Early Events in Cyst Formation and Stepwise Transformation
November 04, 2022 | 10:00 AM - 12:00 PM
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- Primary Cilia Respond to Nutrients Availability and Favor Glutamine Utilization During Metabolic Stress
10:00 AM - 12:00 PM
Primary Cilia Respond to Nutrients Availability and Favor Glutamine Utilization During Metabolic Stress
November 04, 2022 | 10:00 AM - 12:00 PM
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- Polycystin 1 Ciliary Localization Is Controlled by Chemo- and Mechanosensitive Signaling Processes That Involve the Machinery of GPCR Desensitization
10:00 AM - 12:00 PM
Polycystin 1 Ciliary Localization Is Controlled by Chemo- and Mechanosensitive Signaling Processes That Involve the Machinery of GPCR Desensitization
November 04, 2022 | 10:00 AM - 12:00 PM
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- Selective mTORC1 Inhibitors Block Cystogenesis in a Human Kidney Organoid Model of Polycystic Kidney Disease
10:00 AM - 12:00 PM
Selective mTORC1 Inhibitors Block Cystogenesis in a Human Kidney Organoid Model of Polycystic Kidney Disease
November 04, 2022 | 10:00 AM - 12:00 PM
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