ASN's Mission

To create a world without kidney diseases, the ASN Alliance for Kidney Health elevates care by educating and informing, driving breakthroughs and innovation, and advocating for policies that create transformative changes in kidney medicine throughout the world.

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Kidney Week

Clinical Practice Session

Liver-Kidney Connection: Time to Rethink Hepatorenal Syndrome

November 02, 2023 | 04:30 PM - 06:00 PM

Location: Room 201, Pennsylvania Convention Center

Session Description

Accumulating evidence on the pathophysiology of hepatorenal syndrome (HRS) has challenged the conventional model of liver-kidney connection. For example, emerging data point to the heart as the key mediator of untoward kidney effects in HRS. Reliable assessment of kidney function in lieu of various eGFRs and with cystatin C is also potentially changing the way we have defined this syndrome. We discuss the role of point-of-care ultrasound (POCUS) in assessment of volume status in HRS, as well as the benefits and risks of terlipressin therapy in HRS, in light of emerging data and new US Food and Drug Administration approval for this indication.

Learning Objective(s)

  • Explain the emerging evidence on the contribution of cardiac dysfunction to HRS
  • Characterize the role of POCUS in assessment of volume in HRS
  • Summarize the new data on the benefits and risk of terlipressin therapy in HRS
  • Discuss the impact of evolving methods for assessment of kidney function on HRS management

Learning Pathway(s)

  • AKI and Critical Care
  • Pharmacology