ASN's Mission

To create a world without kidney diseases, the ASN Alliance for Kidney Health elevates care by educating and informing, driving breakthroughs and innovation, and advocating for policies that create transformative changes in kidney medicine throughout the world.

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Kidney Week

Clinical Practice Session

Controversies in C3 Glomerulopathy

November 03, 2023 | 04:30 PM - 06:00 PM

Location: Room 201, Pennsylvania Convention Center

Session Description

This session highlights a number of the controversies related to the underlying pathomechanisms, associated biomarkers, and clinical presentation of C3 glomerulopathy (C3G). It concludes with a summary of current management and consideration for initiating targeted therapeutics.

ASN thanks the European Renal Association (ERA) and ERA Ambassador, Dr. Hans Anders.
Session support is provided by an educational grant from Travere Therapeutics, Inc.

Learning Objective(s)

  • Summarize the natural history and clinical confounders of diagnosis of C3G, including PIGN, MGRS, ICGN, and nonspecific complement deposition on kidney biopsies
  • Discuss the application and promise of the peripheral, kidney, and histologic biomarkers of C3G
  • Outline the autoimmune proteins, genetic abnormalities, and novel drivers of complement dysregulation in C3G
  • Describe the standard of care, compassionate use of targeted therapeutics, and the value of trial enrollment for C3G

Learning Pathway(s)

  • Glomerular Diseases