Kidney Week

Clinical Practice Session

Controversies in C3 Glomerulopathy

November 03, 2023 | 04:30 PM - 06:00 PM

Location: Room 201, Pennsylvania Convention Center

Session Description

This session highlights a number of the controversies related to the underlying pathomechanisms, associated biomarkers, and clinical presentation of C3 glomerulopathy (C3G). It concludes with a summary of current management and consideration for initiating targeted therapeutics.

ASN thanks the European Renal Association (ERA) and ERA Ambassador, Dr. Hans Anders.
Session support is provided by an educational grant from Travere Therapeutics, Inc.

Learning Objective(s)

• Summarize the natural history and clinical confounders of diagnosis of C3G, including PIGN, MGRS, ICGN, and nonspecific complement deposition on kidney biopsies
• Discuss the application and promise of the peripheral, kidney, and histologic biomarkers of C3G
• Outline the autoimmune proteins, genetic abnormalities, and novel drivers of complement dysregulation in C3G
• Describe the standard of care, compassionate use of targeted therapeutics, and the value of trial enrollment for C3G

Learning Pathway(s)

• Glomerular Diseases

Moderators

• Joshua M. Thurman, MD
• Marina Vivarelli, MD

Presentations

• What Is C3 Glomerulopathy and What Is It Not?
  04:30 PM - 04:50 PM
  
  • Andrew S. Bomback, MD, MPH
  Andrew S. Bomback, MD, MPH

What Is C3 Glomerulopathy and What Is It Not?

November 03, 2023 | 04:30 PM - 04:50 PM

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• Drivers of C3 Glomerulopathy
  04:50 PM - 05:10 PM
  
  • Hans J. Anders, MD
  Hans J. Anders, MD

Drivers of C3 Glomerulopathy

November 03, 2023 | 04:50 PM - 05:10 PM

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• Role of Biomarkers in C3 Glomerulopathy
  05:10 PM - 05:30 PM
  
  • Veronique Fremeaux Bacchi, MD, PhD
  Veronique Fremeaux Bacchi, MD, PhD

Role of Biomarkers in C3 Glomerulopathy

November 03, 2023 | 05:10 PM - 05:30 PM

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• Standard Immune Suppression and Targeted Therapeutics in C3 Glomerulopathy
  05:30 PM - 05:50 PM
  
  • Carla Marie Nester, MD, MS, FASN
  Carla Marie Nester, MD, MS, FASN

Standard Immune Suppression and Targeted Therapeutics in C3 Glomerulopathy

November 03, 2023 | 05:30 PM - 05:50 PM

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• Q&A
  05:50 PM - 06:00 PM
  

Q&A

November 03, 2023 | 05:50 PM - 06:00 PM

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