Kidney Week

Basic/Clinical Science Session

New Look at Antibody-Mediated Rejection, Including the Barbara T. Murphy, MB BAO BCh, Endowed Lectureship

November 04, 2023 | 10:30 AM - 12:30 PM

Location: Room 115, Pennsylvania Convention Center

Session Description

Antibody-mediated rejection (ABMR) remains the main obstacle to the long-term acceptance of kidney transplant. Our understanding of the mechanisms of ABMR-mediated kidney transplant injuries is evolving. This session provides new insights into cellular and molecular mechanisms leading to ABMR.

ASN gratefully acknowledges Verici Dx, Renalytix, and the American Society of Transplantation for supporting the Barbara T. Murphy, MB BAO BCh, Endowed Lectureship.

Learning Objective(s)

• Describe B cell biology
• Discuss immune regulation and humoral rejection
• Explain follicular T cells
• Describe cytokines and antibody formation

Learning Pathway(s)

• Kidney Transplantation

Moderators

• Enver Akalin, MD, FASN
• Indira Guleria, PhD

Presentations

• Tfh Regulation of Systemic and Graft Alloreactive B Cell Responses After Kidney Transplantation
  10:30 AM - 11:00 AM
  
  • Peter Sage, PhD
  Peter Sage, PhD

Tfh Regulation of Systemic and Graft Alloreactive B Cell Responses After Kidney Transplantation

November 04, 2023 | 10:30 AM - 11:00 AM

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• Dissecting the Mechanisms of Antibody Generation in Response to Kidney Allografts
  11:00 AM - 11:30 AM
  
  • Anna Valujskikh, PhD
  Anna Valujskikh, PhD

Dissecting the Mechanisms of Antibody Generation in Response to Kidney Allografts

November 04, 2023 | 11:00 AM - 11:30 AM

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• Detection of Memory B Cell Responses Before Alloantibody Generation
  11:30 AM - 12:00 PM
  
  • Oriol Bestard, MD, PhD
  Oriol Bestard, MD, PhD

Detection of Memory B Cell Responses Before Alloantibody Generation

November 04, 2023 | 11:30 AM - 12:00 PM

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• Novel Therapeutic Targets to Control Humoral Responses in Desensitization and ABMR: The Barbara T. Murphy, MB BAO BCh, Endowed Lectureship
  12:00 PM - 12:30 PM
  
  • Flavio Vincenti, MD
  Flavio Vincenti, MD

Novel Therapeutic Targets to Control Humoral Responses in Desensitization and ABMR: The Barbara T. Murphy, MB BAO BCh, Endowed Lectureship

November 04, 2023 | 12:00 PM - 12:30 PM

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