ASN's Mission

To create a world without kidney diseases, the ASN Alliance for Kidney Health elevates care by educating and informing, driving breakthroughs and innovation, and advocating for policies that create transformative changes in kidney medicine throughout the world.

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Kidney Week

Basic/Clinical Science Session

Genetic Strategies to Guide Therapeutic Development

November 04, 2023 | 02:00 PM - 04:00 PM

Location: Room 108, Pennsylvania Convention Center

Session Description

The last decade has seen renewed investment in gene editing in the form of CRISPR and RNA editing for applications in common disorders, cancer, and genetic diseases. In this session, the potential applications of these genetic-based technologies to kidney and related diseases are reviewed.

Learning Objective(s)

  • Provide an approach to RNA-based therapies in CKD
  • Develop an approach to RNA-based therapies in APOL1
  • Summarize progress of developing gene editing therapy in IgA nephropathy
  • Discuss gene read through therapy in Alport syndrome

Learning Pathway(s)

  • Genetic Diseases and Development