Kidney Week

Basic/Clinical Science Session

Podocytopathy in Aging: Advances and Unanswered Questions

November 04, 2023 | 02:00 PM - 04:00 PM

Location: Room 103, Pennsylvania Convention Center

Session Description

This session explores recent advances in our understanding of the biology of aging in podocytes. The session highlights (1) novel insights into the mechanisms of podocyte aging in health and disease, (2) innovative models of the effects of aging on glomerular function, and (3) recent insights into the mechanisms of podocyte injury and repair and the contributions of mitochondrial dysfunction in aging.

Support is provided by an educational grant from Travere Therapeutics, Inc.

Learning Objective(s)

• Explain the molecular underpinnings of podocyte dysfunction in aging
• Discuss innovative models of podocyte injury and repair in aging
• Define the role of mitochondrial homeostasis in the aging podocyte
• Identify novel candidate therapies for podocyte dysfunction in aging

Learning Pathway(s)

• Glomerular Diseases
• Pathology

Moderators

• Jeffrey H. Miner, PhD, FASN
• Clintoria R. Williams, PhD

Presentations

• Podocyte Mitochondria as Therapeutic Targets in Aging
  02:00 PM - 02:30 PM
  
  • Mariya T. Sweetwyne, PhD
  Mariya T. Sweetwyne, PhD

Podocyte Mitochondria as Therapeutic Targets in Aging

November 04, 2023 | 02:00 PM - 02:30 PM

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• Exploring the GSK3b as a Therapeutic Target in Podocyte Senescence
  02:30 PM - 03:00 PM
  
  • Rujun Gong, MD, PhD, FASN
  Rujun Gong, MD, PhD, FASN

Exploring the GSK3b as a Therapeutic Target in Podocyte Senescence

November 04, 2023 | 02:30 PM - 03:00 PM

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• HDACs and Podocyte Senescence: Novel Therapeutic Targets?
  03:00 PM - 03:30 PM
  
  • Shuta Ishibe, MD
  Shuta Ishibe, MD

HDACs and Podocyte Senescence: Novel Therapeutic Targets?

November 04, 2023 | 03:00 PM - 03:30 PM

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• Considering the Role of REST in Podocyte Aging
  03:30 PM - 04:00 PM
  
  • Guillaume Canaud, MD, PhD
  Guillaume Canaud, MD, PhD

Considering the Role of REST in Podocyte Aging

November 04, 2023 | 03:30 PM - 04:00 PM

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