Kidney Week

Translational Session

Sepsis-Associated AKI: Pathophysiology to Subphenotypes to Treatments

November 06, 2025 | 04:30 PM - 06:00 PM

Location: General Assembly B, Convention Center

Session Description

AKI is a common complication in patients with sepsis. This session provides an overview of the pathophysiology of sepsis-associated AKI, research into the identification of AKI subphenotypes, and future potential therapeutics in sepsis-associated AKI.

Learning Objective(s)

• Explain the underlying pathophysiology in sepsis-associated AKI
• Identify methodologies to determine subphenotypes in sepsis-associated AKI and implications for clinical care
• Discuss novel therapeutics in sepsis-associated AKI and what is on the horizon

Learning Pathway(s)

• AKI and Critical Care
• Kidney Biology and Physiology

Moderators

• Linda Awdishu, PharmD, MA, FASN
• Bryan R. Kestenbaum, MD, MS

Presentations

• Pathophysiology in Sepsis-Associated AKI
  04:30 PM - 04:50 PM
  
  • Natalja L. Stanski, MD, MS

Pathophysiology in Sepsis-Associated AKI

November 06, 2025 | 04:30 PM - 04:50 PM

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• Identification of Subphenotypes in Sepsis-Associated AKI
  04:50 PM - 05:10 PM
  
  • Elizabeth Kiernan, MD

Identification of Subphenotypes in Sepsis-Associated AKI

November 06, 2025 | 04:50 PM - 05:10 PM

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• Recombinant Alkaline Phosphatase for Sepsis-Associated AKI
  05:10 PM - 05:30 PM
  
  • Peter Pickkers, MD, PhD

Recombinant Alkaline Phosphatase for Sepsis-Associated AKI

November 06, 2025 | 05:10 PM - 05:30 PM

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• What Is on the Horizon in AKI Therapeutics?
  05:30 PM - 05:50 PM
  
  • Matthieu Legrand, MD, PhD

What Is on the Horizon in AKI Therapeutics?

November 06, 2025 | 05:30 PM - 05:50 PM

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• Q&A
  05:50 PM - 06:00 PM
  

Q&A

November 06, 2025 | 05:50 PM - 06:00 PM

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