Kidney Week

Basic/Clinical Science Session

Leading Edge of Therapeutic Development in Cystic Kidney Diseases

November 06, 2025 | 02:00 PM - 04:00 PM

Location: Room 310A, Convention Center

Session Description

Advanced mechanistic understanding of rare genetic cystic kidney diseases has furthered therapeutic target identification and progress toward clinical trials. This session highlights diverse treatment approaches and opportunities and challenges in advancement to clinical trials.

Learning Objective(s)

• Explain drug repurposing
• Compare and contrast therapeutic target identification across diverse rare kidney diseases
• Describe cellular drug screening paradigms

Learning Pathway(s)

• Genetic Diseases and Development

Moderators

• Whitney Besse, MD
• Ali G. Gharavi, MD

Presentations

• Therapeutic Approaches for Nephronophthisis and Renal Ciliopathies
  02:00 PM - 02:30 PM
  
  • Sophie Saunier, PhD

Therapeutic Approaches for Nephronophthisis and Renal Ciliopathies

November 06, 2025 | 02:00 PM - 02:30 PM

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• Promising Drug Targets and Prospects for Clinical Trials in Renal Ciliopathies
  02:30 PM - 03:00 PM
  
  • John Andrew Sayer, MBChB, PhD

Promising Drug Targets and Prospects for Clinical Trials in Renal Ciliopathies

November 06, 2025 | 02:30 PM - 03:00 PM

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• Temporal Transcriptomics in PKD Models to Identify Drug Targets
  03:00 PM - 03:30 PM
  
  • Abigail O'Regan Smith, MD, PhD

Temporal Transcriptomics in PKD Models to Identify Drug Targets

November 06, 2025 | 03:00 PM - 03:30 PM

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• siRNA Therapy Using Nanoparticles to Treat PKD
  03:30 PM - 04:00 PM
  
  • Eun ji Chung, PhD

siRNA Therapy Using Nanoparticles to Treat PKD

November 06, 2025 | 03:30 PM - 04:00 PM

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