- Allelic Dissection of Pkd1 3′-UTR Architecture Uncovers Regulatory Elements Affecting ADPKD Progression
10:00 AM - 12:00 PM
Allelic Dissection of Pkd1 3′-UTR Architecture Uncovers Regulatory Elements Affecting ADPKD Progression
November 07, 2025 | 10:00 AM - 12:00 PM
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- Mitigation of Cystogenesis in ADPKD: Role of IP1 Deficiency in Modulating the Balance Between Autophagy and Apoptosis
10:00 AM - 12:00 PM
Mitigation of Cystogenesis in ADPKD: Role of IP1 Deficiency in Modulating the Balance Between Autophagy and Apoptosis
November 07, 2025 | 10:00 AM - 12:00 PM
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- Polycystin-1 Regulates Cilia-Dependent Hippo Signaling in ADPKD
10:00 AM - 12:00 PM
Polycystin-1 Regulates Cilia-Dependent Hippo Signaling in ADPKD
November 07, 2025 | 10:00 AM - 12:00 PM
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- Tracking Murine ADPKD Progression via Resazurin Dye-Based Tubular Function Assessment
10:00 AM - 12:00 PM
Tracking Murine ADPKD Progression via Resazurin Dye-Based Tubular Function Assessment
November 07, 2025 | 10:00 AM - 12:00 PM
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- Development of a High-Throughput Three-Dimensional (3D) Tubulogenesis Assay to Study ADPKD Gene Function
10:00 AM - 12:00 PM
Development of a High-Throughput Three-Dimensional (3D) Tubulogenesis Assay to Study ADPKD Gene Function
November 07, 2025 | 10:00 AM - 12:00 PM
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- Pkd1 Deletion in Renal Fibroblasts Drives Spontaneous Differentiation to Migratory, Matrix-Producing Myofibroblasts with Altered Metabolism
10:00 AM - 12:00 PM
Pkd1 Deletion in Renal Fibroblasts Drives Spontaneous Differentiation to Migratory, Matrix-Producing Myofibroblasts with Altered Metabolism
November 07, 2025 | 10:00 AM - 12:00 PM
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- Epigenetic Studies in Pkd1 and Pkd2 Conditional Knockout Reveal Mechanism of Suppression of Cholesterol Biosynthesis and Altered Mitochondrial Function
10:00 AM - 12:00 PM
Epigenetic Studies in Pkd1 and Pkd2 Conditional Knockout Reveal Mechanism of Suppression of Cholesterol Biosynthesis and Altered Mitochondrial Function
November 07, 2025 | 10:00 AM - 12:00 PM
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- Determining the Role of GPR161 in PKD
10:00 AM - 12:00 PM
Determining the Role of GPR161 in PKD
November 07, 2025 | 10:00 AM - 12:00 PM
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- Drug Treatment Approaches for HNF1B-Related Cystic Kidney Disease in a Mouse Model
10:00 AM - 12:00 PM
Drug Treatment Approaches for HNF1B-Related Cystic Kidney Disease in a Mouse Model
November 07, 2025 | 10:00 AM - 12:00 PM
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- Combined Tolvaptan and Renal Denervation in a Rat Model of Autosomal Recessive Polycystic Kidney Disease (ARPKD)
10:00 AM - 12:00 PM
Combined Tolvaptan and Renal Denervation in a Rat Model of Autosomal Recessive Polycystic Kidney Disease (ARPKD)
November 07, 2025 | 10:00 AM - 12:00 PM
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- EB1-Regulated Microtubule Dynamics Drive Cyst Formation in ADPKD
10:00 AM - 12:00 PM
EB1-Regulated Microtubule Dynamics Drive Cyst Formation in ADPKD
November 07, 2025 | 10:00 AM - 12:00 PM
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- Intravital Imaging of Intact Kidney Tubules in Live Pkd1 Targeted Mice Using Upright Two-Photon Microscopy
10:00 AM - 12:00 PM
Intravital Imaging of Intact Kidney Tubules in Live Pkd1 Targeted Mice Using Upright Two-Photon Microscopy
November 07, 2025 | 10:00 AM - 12:00 PM
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- Effects of Pkd1 Deficiency on the Response to Endoplasmic Reticulum Stress Induced by Tunicamycin
10:00 AM - 12:00 PM
Effects of Pkd1 Deficiency on the Response to Endoplasmic Reticulum Stress Induced by Tunicamycin
November 07, 2025 | 10:00 AM - 12:00 PM
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- PKD1-FBW7 Axis in Proximal Tubules Drives Kidney Function in ADPKD
10:00 AM - 12:00 PM
PKD1-FBW7 Axis in Proximal Tubules Drives Kidney Function in ADPKD
November 07, 2025 | 10:00 AM - 12:00 PM
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- Effect of Tolvaptan in Combination with Rapamycin in a Rat Model of PKD
10:00 AM - 12:00 PM
Effect of Tolvaptan in Combination with Rapamycin in a Rat Model of PKD
November 07, 2025 | 10:00 AM - 12:00 PM
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- Gut Barrier Disruption Exacerbates PKD and Is Ameliorated by Tributyrin Supplementation
10:00 AM - 12:00 PM
Gut Barrier Disruption Exacerbates PKD and Is Ameliorated by Tributyrin Supplementation
November 07, 2025 | 10:00 AM - 12:00 PM
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- Preserving Polycystin-1 Function in ADPKD by Targeting G4 DNA in PKD1
10:00 AM - 12:00 PM
Preserving Polycystin-1 Function in ADPKD by Targeting G4 DNA in PKD1
November 07, 2025 | 10:00 AM - 12:00 PM
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- Proteomic Characterization of ADPKD Pathogenesis in Monoclonal mIMCD3 Cells
10:00 AM - 12:00 PM
Proteomic Characterization of ADPKD Pathogenesis in Monoclonal mIMCD3 Cells
November 07, 2025 | 10:00 AM - 12:00 PM
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- Pirfenidone Treatment Attenuates Fibrosis in ADPKD
10:00 AM - 12:00 PM
Pirfenidone Treatment Attenuates Fibrosis in ADPKD
November 07, 2025 | 10:00 AM - 12:00 PM
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- Synthetic Protein Circuits Trigger Programmable Cystic Cell Death in ADPKD
10:00 AM - 12:00 PM
Synthetic Protein Circuits Trigger Programmable Cystic Cell Death in ADPKD
November 07, 2025 | 10:00 AM - 12:00 PM
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- Nuclear Translocation of Activation-Induced Cytidine Deaminase (AID) in ADPKD Tissue Reveals a Mechanism for Second Hit Mutations Leading to ADPKD
10:00 AM - 12:00 PM
Nuclear Translocation of Activation-Induced Cytidine Deaminase (AID) in ADPKD Tissue Reveals a Mechanism for Second Hit Mutations Leading to ADPKD
November 07, 2025 | 10:00 AM - 12:00 PM
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- Novel Gene Therapy for ADPKD Based on CFTR
10:00 AM - 12:00 PM
Novel Gene Therapy for ADPKD Based on CFTR
November 07, 2025 | 10:00 AM - 12:00 PM
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- RhoA and Its Downstream Effectors ROCK/Cofilin and Formin Trigger Mitochondrial Fragmentation in PKD
10:00 AM - 12:00 PM
RhoA and Its Downstream Effectors ROCK/Cofilin and Formin Trigger Mitochondrial Fragmentation in PKD
November 07, 2025 | 10:00 AM - 12:00 PM
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- SetD7-PKA Feedforward Signaling Enhances Cyst Growth in ADPKD
10:00 AM - 12:00 PM
SetD7-PKA Feedforward Signaling Enhances Cyst Growth in ADPKD
November 07, 2025 | 10:00 AM - 12:00 PM
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- SCO-792, an Enteropeptidase Inhibitor, Slows Development of Renal and Hepatic Cysts in a Mouse Model of ADPKD
10:00 AM - 12:00 PM
SCO-792, an Enteropeptidase Inhibitor, Slows Development of Renal and Hepatic Cysts in a Mouse Model of ADPKD
November 07, 2025 | 10:00 AM - 12:00 PM
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- Klotho Attenuates ADPKD Progression by Epigenetic Reprogramming and Multimodal Suppression of Cystogenic Pathways
10:00 AM - 12:00 PM
Klotho Attenuates ADPKD Progression by Epigenetic Reprogramming and Multimodal Suppression of Cystogenic Pathways
November 07, 2025 | 10:00 AM - 12:00 PM
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- Ciliary ARL13B Drives Renal Cystogenesis via Its GEF Activity for ARL3
10:00 AM - 12:00 PM
Ciliary ARL13B Drives Renal Cystogenesis via Its GEF Activity for ARL3
November 07, 2025 | 10:00 AM - 12:00 PM
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- Novel Endogenous Pkd1 Reexpression Allele and Effects of Mosaic Reexpression of Pkd1 in ADPKD
10:00 AM - 12:00 PM
Novel Endogenous Pkd1 Reexpression Allele and Effects of Mosaic Reexpression of Pkd1 in ADPKD
November 07, 2025 | 10:00 AM - 12:00 PM
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- Cilia-Dependent Cyst Growth Linked to Tryptophan Metabolism in PKD
10:00 AM - 12:00 PM
Cilia-Dependent Cyst Growth Linked to Tryptophan Metabolism in PKD
November 07, 2025 | 10:00 AM - 12:00 PM
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- AARS1 Mediates Lactylation of STAT3 and NF-kB Promotes Cyst Growth in ADPKD
10:00 AM - 12:00 PM
AARS1 Mediates Lactylation of STAT3 and NF-kB Promotes Cyst Growth in ADPKD
November 07, 2025 | 10:00 AM - 12:00 PM
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- Precise DCLK1 Protein Degradation via PROTAC Delays Cyst Growth in ADPKD
10:00 AM - 12:00 PM
Precise DCLK1 Protein Degradation via PROTAC Delays Cyst Growth in ADPKD
November 07, 2025 | 10:00 AM - 12:00 PM
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- SIRT3 Suppresses Cyst Growth via Enhancing Mitochondrial Function in ADPKD
10:00 AM - 12:00 PM
SIRT3 Suppresses Cyst Growth via Enhancing Mitochondrial Function in ADPKD
November 07, 2025 | 10:00 AM - 12:00 PM
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- Rationally Engineered Miniaturized Plasmids Improve Transgene Delivery and CRISPR Activation of PKD1 in Primary Kidney Cells
10:00 AM - 12:00 PM
Rationally Engineered Miniaturized Plasmids Improve Transgene Delivery and CRISPR Activation of PKD1 in Primary Kidney Cells
November 07, 2025 | 10:00 AM - 12:00 PM
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- Potential One-Time Lipid Nanoparticle-Driven Gene Editing Therapy to Address ADPKD Caused by PKD1 Mutations
10:00 AM - 12:00 PM
Potential One-Time Lipid Nanoparticle-Driven Gene Editing Therapy to Address ADPKD Caused by PKD1 Mutations
November 07, 2025 | 10:00 AM - 12:00 PM
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- Resolvin D1 Attenuates Renal Inflammation and Cyst Growth in Mice with PKD
10:00 AM - 12:00 PM
Resolvin D1 Attenuates Renal Inflammation and Cyst Growth in Mice with PKD
November 07, 2025 | 10:00 AM - 12:00 PM
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- Loss of Inositol Polyphosphate-5-Phosphatase E in Adult Mouse Kidneys Causes Slow, Progressive Renal Cystogenesis
10:00 AM - 12:00 PM
Loss of Inositol Polyphosphate-5-Phosphatase E in Adult Mouse Kidneys Causes Slow, Progressive Renal Cystogenesis
November 07, 2025 | 10:00 AM - 12:00 PM
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- Pkd1 and Itgb1 Genetic Interaction Studies Suggest Minor Improvement in Cystic Disease, Pronounced Reduction in YAP Activation in Cysts, and Complex Effects on Itgb1-Associated Perinatal Lethality
10:00 AM - 12:00 PM
Pkd1 and Itgb1 Genetic Interaction Studies Suggest Minor Improvement in Cystic Disease, Pronounced Reduction in YAP Activation in Cysts, and Complex Effects on Itgb1-Associated Perinatal Lethality
November 07, 2025 | 10:00 AM - 12:00 PM
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- Suppression of ADPKD Alters Epithelial Cell Transcription Program
10:00 AM - 12:00 PM
Suppression of ADPKD Alters Epithelial Cell Transcription Program
November 07, 2025 | 10:00 AM - 12:00 PM
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- Deflating the Disease: VEGFR2 Blockade as a Novel Therapeutic Strategy in PKD
10:00 AM - 12:00 PM
Deflating the Disease: VEGFR2 Blockade as a Novel Therapeutic Strategy in PKD
November 07, 2025 | 10:00 AM - 12:00 PM
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- Cross-Model Single-Cell and Spatial Atlas Reveals the Involvement of Spp1 in the Progression of PKD
10:00 AM - 12:00 PM
Cross-Model Single-Cell and Spatial Atlas Reveals the Involvement of Spp1 in the Progression of PKD
November 07, 2025 | 10:00 AM - 12:00 PM
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- Versatile HaloTag Resource Illuminates PKD2 Localization and Turnover
10:00 AM - 12:00 PM
Versatile HaloTag Resource Illuminates PKD2 Localization and Turnover
November 07, 2025 | 10:00 AM - 12:00 PM
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- Defined Dietary Intervention Overrides Injury-Accelerated Cystogenesis in a Mouse Model of ADPKD
10:00 AM - 12:00 PM
Defined Dietary Intervention Overrides Injury-Accelerated Cystogenesis in a Mouse Model of ADPKD
November 07, 2025 | 10:00 AM - 12:00 PM
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- Transcriptomic Analysis of Pkd1 Mutant Mice Reveals Novel Pathways of Dysfunction During Early Cystogenesis
10:00 AM - 12:00 PM
Transcriptomic Analysis of Pkd1 Mutant Mice Reveals Novel Pathways of Dysfunction During Early Cystogenesis
November 07, 2025 | 10:00 AM - 12:00 PM
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- Spatial Transcriptomics Reveals New ADPKD-Specific Genes
10:00 AM - 12:00 PM
Spatial Transcriptomics Reveals New ADPKD-Specific Genes
November 07, 2025 | 10:00 AM - 12:00 PM
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- Spatially Defining the ADPKD Transcriptome
10:00 AM - 12:00 PM
Spatially Defining the ADPKD Transcriptome
November 07, 2025 | 10:00 AM - 12:00 PM
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- Thyroxine as a Pleiotropic Modulator in ADPKD: Insights from Engineered Tubules, In Vivo Models, and Patients
10:00 AM - 12:00 PM
Thyroxine as a Pleiotropic Modulator in ADPKD: Insights from Engineered Tubules, In Vivo Models, and Patients
November 07, 2025 | 10:00 AM - 12:00 PM
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- Selective Peroxisome Proliferator-Activated Receptor-α (PPARα) Modulator Inhibits Cyst Enlargement in PKD
10:00 AM - 12:00 PM
Selective Peroxisome Proliferator-Activated Receptor-α (PPARα) Modulator Inhibits Cyst Enlargement in PKD
November 07, 2025 | 10:00 AM - 12:00 PM
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- Increased Levels of Endogenous Retroviruses Promote Cyst Growth in ADPKD
10:00 AM - 12:00 PM
Increased Levels of Endogenous Retroviruses Promote Cyst Growth in ADPKD
November 07, 2025 | 10:00 AM - 12:00 PM
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- Combined Treatment with Tolvaptan and TGFB Receptor Type-1 Inhibitor SB525334 Preserves Renal Function and Prevents Renal Fibrosis Better than Tolvaptan Alone in a Mouse Model of ADPKD
10:00 AM - 12:00 PM
Combined Treatment with Tolvaptan and TGFB Receptor Type-1 Inhibitor SB525334 Preserves Renal Function and Prevents Renal Fibrosis Better than Tolvaptan Alone in a Mouse Model of ADPKD
November 07, 2025 | 10:00 AM - 12:00 PM
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- Interferon Gamma Drives Rapidly Progressing Cystic Kidney Diseases
10:00 AM - 12:00 PM
Interferon Gamma Drives Rapidly Progressing Cystic Kidney Diseases
November 07, 2025 | 10:00 AM - 12:00 PM
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- In Situ Analysis of Drug and Metabolite Distribution in a Three-Dimensional In Vivo Cyst Model of ADPKD Using Desorption Electrospray Ionization-Mass Spectrometry (DESI-MS)
10:00 AM - 12:00 PM
In Situ Analysis of Drug and Metabolite Distribution in a Three-Dimensional In Vivo Cyst Model of ADPKD Using Desorption Electrospray Ionization-Mass Spectrometry (DESI-MS)
November 07, 2025 | 10:00 AM - 12:00 PM
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- Comparative Transcriptomic Analysis of Polycystic Kidneys and Livers from Patients with ADPKD Reveals Organ-Specific Alterations in Transcriptional Profiles and Associated Signaling Pathways
10:00 AM - 12:00 PM
Comparative Transcriptomic Analysis of Polycystic Kidneys and Livers from Patients with ADPKD Reveals Organ-Specific Alterations in Transcriptional Profiles and Associated Signaling Pathways
November 07, 2025 | 10:00 AM - 12:00 PM
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- Molecular and Cyst-Type Composition Heterogeneity in Human ADPKD
10:00 AM - 12:00 PM
Molecular and Cyst-Type Composition Heterogeneity in Human ADPKD
November 07, 2025 | 10:00 AM - 12:00 PM
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- Cellular Senescence Is Associated with Disease Progression in ADPKD
10:00 AM - 12:00 PM
Cellular Senescence Is Associated with Disease Progression in ADPKD
November 07, 2025 | 10:00 AM - 12:00 PM
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- Critical Role of the Proto-Oncogene c-KIT in Tuberous Sclerosis Complex (TSC)-Associated Kidney Cystogenesis
10:00 AM - 12:00 PM
Critical Role of the Proto-Oncogene c-KIT in Tuberous Sclerosis Complex (TSC)-Associated Kidney Cystogenesis
November 07, 2025 | 10:00 AM - 12:00 PM
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- Kidney Cyst Epithelia in Tuberous Sclerosis Complex Exhibit Expansion of A-Intercalated but Loss of B-Intercalated and Principal Cells: Role of FOXI1, FOXP1, and DMRT2 Transcription Factors
10:00 AM - 12:00 PM
Kidney Cyst Epithelia in Tuberous Sclerosis Complex Exhibit Expansion of A-Intercalated but Loss of B-Intercalated and Principal Cells: Role of FOXI1, FOXP1, and DMRT2 Transcription Factors
November 07, 2025 | 10:00 AM - 12:00 PM
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- Unique Apical Localization of AQP6 on Cyst Epithelium May Point to Its Role in Fluid Secretion into the Cyst Lumen in Tuberous Sclerosis Complex
10:00 AM - 12:00 PM
Unique Apical Localization of AQP6 on Cyst Epithelium May Point to Its Role in Fluid Secretion into the Cyst Lumen in Tuberous Sclerosis Complex
November 07, 2025 | 10:00 AM - 12:00 PM
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- Therapeutic Targeting of Ire1alpha Endoribonuclease Domain Ameliorates ADPKD in Orthologous Mouse Models
10:00 AM - 12:00 PM
Therapeutic Targeting of Ire1alpha Endoribonuclease Domain Ameliorates ADPKD in Orthologous Mouse Models
November 07, 2025 | 10:00 AM - 12:00 PM
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- Novel Drug TJ0113 Induces Mitochondrial Autophagy to Ameliorate Murine ADPKD
10:00 AM - 12:00 PM
Novel Drug TJ0113 Induces Mitochondrial Autophagy to Ameliorate Murine ADPKD
November 07, 2025 | 10:00 AM - 12:00 PM
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