IgA And SLE 50 minutes ago

26 yo Hispanic F with hx of SLE ( skin, joint) and strong family hx of SLE referred by Rheumatologist for proteinuria, hematuria. On HQ, oral stero...

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Transplant Centers for 100% Sensitized and Recurrent FSGS History 1 hour ago

Hi, reaching out to this forum to see if anyone knows of centers taking on more complex patients such as my current patient who is a 35 year old fe...

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RE: Help Needed 2 hours ago

A high resolution CT will also reveal chest lymph nodes which may be a better target for biopsy by EBUS . ------------------------------ Satish ...

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RE: IgA nephropathy 3 hours ago

I think you have to base your treatment mostly on the clinical presentation, proteinuria and hematuria , not the biopsy The creatinine is not nor...

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IgA nephropathy 3 hours ago

Hello, would appreciate your opinion on this one 40M diagnosed with IgA nephropathy 2023, creat 90-100 umol/l, proteinuria 2.4 g/day. kidney bi...

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RE: SIADH in a patient with SAH 6 hours ago

To the extent that a new independent thread, “Help Needed”, has been created (and been active as such since; thanks to Drs Glassock and Rodby), the...

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RE: SIADH in a patient with SAH 8 hours ago

Seems not --------------------------------- Dr. Hormaz Dastoor. MD, FASN Nephrology Consultant - Seha Kidney Care. Nephrology Consultant- SSMC,Pur...

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RE: SIADH in a patient with SAH 10 hours ago

Thanks; all error fixed as per your advice. Sent from my iPhone

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RE: IgA nephropathy in a diabetic, mesangial deposits with chronicity elsewhere, role for IS 12 hours ago

Dr. Venkat. Thanks for your great comment. This patient has Class II DN according to the 2010 RPS classification system , with severe arterioloneph...

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RE: SIADH in a patient with SAH 15 hours ago

try Post New Message ------------------------------ Roger Rodby MD, FASN Professor of Medicine Rush University Nephrology Associates Chicago ...

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RE: IgA nephropathy in a diabetic, mesangial deposits with chronicity elsewhere, role for IS 15 hours ago

If I may butt in, The proteinuria with unimpressive mesangial disease does not dissuade me from diabetic nephropathy: https://link.springer.com...

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RE: Help Needed 18 hours ago

Will repeat urine studies at his next visit, as you suggest. Thanks also for reminding us of the mechanistic link between elevated SACE, and renal...

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RE: IgA nephropathy in a diabetic, mesangial deposits with chronicity elsewhere, role for IS 18 hours ago

Dr. Glassock: Wanted to ask you about clinicopathological correlations in diabetic glomerulopathy. This patient has global GBM thickening but only ...

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RE: Help Needed 18 hours ago

Thanks! Sent from my iPhone

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RE: Double positive ANCA 18 hours ago

Forgive me for posting this but I do it every chance I get. ------------------------------ Roger Rodby MD, FASN Professor of Medicine Rush U...

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RE: Help Needed 18 hours ago

IF this is tubulointerstital as suggested by ACE and HyperCa, his AC ratio should be low compared to his PCr ratio. Can you get simultaneous PCR ...

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RE: Help Needed 19 hours ago

Serum PTH -RP levels are elevated fairly commonly in Sarcoidoisis. I see no particular reason to pursue a cancer diagnosis in this case. I would fa...

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RE: Help Needed 20 hours ago

Increase in SCr occurred in about a year. UPCR was 0.892, the last time checked; not much changed since before the onset of hypercalcemia. As sug...

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RE: Help Needed 20 hours ago

Many thanks.. Will have him scheduled for high-resolution chest CT, asap; and will discuss renal bx prospects with him. Sent from my iPhone

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RE: Double positive ANCA 21 hours ago

I fully agree with Dr, Rodby as most patient diagnosed with this condition have received some sort of IS therapy in addition to stopping Hydralazin...

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RE: Double positive ANCA 22 hours ago

functional solitary kidney She had cr 4.7 up from 1.4. I would not assume stopping the drug alone would be enough I would treat with Pexivas ...

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RE: Help Needed 22 hours ago

In my opinion- hypercalcemia, suppressed iPTH, slightly elevated PTH -RP, normal 1,25 DI-hydroxy Vitamin D and elevated ACE is most compatible with...

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RE: Help Needed 22 hours ago

what is in the urine? PC ratio AC ratio Over what time did the S Cr go from 1.7 to 2.5? IS that PTH related protein elevated? Im thinking m...

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RE: IgA nephropathy in a diabetic, mesangial deposits with chronicity elsewhere, role for IS 22 hours ago

Hyaline arterionephrosclerosis, Glomerulosclerosis, increased mesangial matrix and thickening of GBM (by EM) all indicate the presence of DN. As fa...

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RE: IgA nephropathy in a diabetic, mesangial deposits with chronicity elsewhere, role for IS 23 hours ago

Thank you for the continued enlightenment the forum provides. From the abscence of glomerular basement thickening and linear staining , can a diagn...

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Help Needed 1 day ago

Help needed: 60 WM, retired air traffic contractor with FAA (helped in upgrading control towers). H/o CKD (baseline SCr 1.5; presumed from DM, HT...

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RE: Progressive IgA 1 day ago

These desperate measures either work or they do not (as Shakespeare noted) - positive results reported in the literature are of little help, due to...

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RE: Progressive IgA 1 day ago

I have had some experience with using PLEX and then giving eculizumab. This has been the last ditch effort for me in these patients who have been r...

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RE: IgA nephropathy in a diabetic, mesangial deposits with chronicity elsewhere, role for IS 1 day ago

Dr. Dastoor is quite correct - IgAN and Diabetuc Nephropstgyv can ocurr together (like in tgus case) perhaps more commonly than chance alone and in...

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RE: IgA nephropathy in a diabetic, mesangial deposits with chronicity elsewhere, role for IS 1 day ago

I agree with Dr. Glassock , that the hematuria may be a red herring .. in that it could be due to DN or IgAN. However at the same time the mesangi...

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RE: IgA nephropathy in a diabetic, mesangial deposits with chronicity elsewhere, role for IS 1 day ago

Difficult case. The only sign of ongoing active inflammation is the hematuria which might also be caused by DN. I am guessing that the increasing p...

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IgA nephropathy in a diabetic, mesangial deposits with chronicity elsewhere, role for IS 1 day ago

A 67-year-old obese white male with known IgA nephropathy diagnosed in 2018 (I am not able to access his biopsy) type 2 diabetes on oral meds. The ...

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RE: SIADH in a patient with SAH 1 day ago

Couldn't find "create" icon. ------------------------------ Tunde Tijani, MD [Nephrology] McConnellsburg, PA 717 977-1785 -----------------------...

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RE: SIADH in a patient with SAH 1 day ago

just copy your message and repost it in a new post under create ------------------------------ Roger Rodby MD, FASN Professor of Medicine Ru...

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RE: SIADH in a patient with SAH 1 day ago

Will try; if only I knew precisely how to correct the error. Sent from my iPhone

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RE: Progressive IgA 1 day ago

Unfortunately ,these are "fire-walled" reports so one cannot access the details without a Journal subscription. It is noteworthy that this patient ...

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RE: SIADH in a patient with SAH 1 day ago

Dr. Tijani- Could you please delete this case from this thread and repost it as a new post. It is very confusing to try to discuss two very diffe...

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RE: Progressive IgA 1 day ago

I know this is "from left field" but does the "smudgy " deposits of IgA make Fibrillary GN a very remote possibility? No EM performed. If a DNAJB9 ...

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RE: Progressive IgA 1 day ago

Good point. I have no personal experience with Eculizumab in progressive IgAN . Does the degree of chronic changes in this biopsy make one skeptica...

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RE: Double positive ANCA 1 day ago

This is undoubtedly a case of Hydralazine induced vasculitis- full or partial recovery is expected with permanent discontinuance of Hydralazine . A...

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RE: SIADH in a patient with SAH 1 day ago

What is or was the volume status , was he euvolemic or hypovolemic . You mentioned his Una being 150 mmol/l , but what was his daily urine volume ...

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RE: Progressive IgA 2 days ago

Few case reports for use of Eculizumab , in severe progressive , steroid resistant IgAN https://www.amjtransplant.org/article/S1600-6135(23)00519...

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RE: Double positive ANCA 2 days ago

This chart is self explanatory ------------------------------ Dr. Hormaz Dastoor. MD, FASN Nephrology Consultant - Seha Kidney Care. Nephrology C...

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RE: SIADH in a patient with SAH 2 days ago

Removed.

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RE: Double positive ANCA 2 days ago

Yes, I was able to have a family member bring in her medications and she is on hydralazine My understanding is that with her renal failure to trea...

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RE: Progressive IgA 2 days ago

He and his Family deny skin rash , abdominal pain/GI bleeding, and Joint symptoms on review ------------------------------ Alamri MD ----------...

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RE: Progressive IgA 2 days ago

How confident are you that this is not IgA Vasculitis? Is there any history of skin rashes, abdominal pain or arthralgias. . If yes, I might consid...

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RE: Progressive IgA 2 days ago

With only 1 crescent in 12 non-sclerotic glomeruli and a course of declining GFR over 7 months I do not think this is RPGN with extensive crescents...

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RE: Progressive IgA 2 days ago

So Dr. Glassock, you are suggesting optimizing his antiproteinuric medications and to keep him on maximally supportive therapy Do you have any...

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RE: Double positive ANCA 2 days ago

Any hydralazine or allopurinol use in this patient ? --------------------------------- Edgard Wehbe MD, FASN Wichita Nephrology Group Wichita K...

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