ASN's Mission

ASN leads the fight to prevent, treat, and cure kidney diseases throughout the world by educating health professionals and scientists, advancing research and innovation, communicating new knowledge, and advocating for the highest quality care for patients.

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Kidney Week

Basic/Clinical Science Session

Kidney, Bone, and Vasculature: Is the Gut a New Piece of the Puzzle?

November 09, 2019 | 10:30 AM - 12:30 PM

Location: 145, Walter E. Washington Convention Center

Session Description

Patients with CKD exhibit a disproportionate burden of cardiovascular mortality, which likely stems from the presence of unique, nontraditional risk factors that accompany deteriorating kidney function. Mounting evidence suggests that alterations to the intestinal microbiome in CKD may serve as one such risk factor.

Learning Objective(s)

  • Describe the microbiome-mediated mechanisms associated with CKD-MBD
  • Discuss how intestinal barrier dysfunction leads to bacterial translocation and endotoxemia that potentiate systemic inflammation
  • Describe the accumulation of dietary-derived bacterial byproducts that stimulate pathways promoting atheromatous changes in arteries and cardiovascular disease

Learning Pathway(s)

  • Bone and Mineral Metabolism


  • Linda F. Fried, MD, MPH, FASN
  • Dominic S. Raj, MD, MBBS, FASN


  • The Role of Gut Microbiota on the Anabolic and Catabolic Effects of PTH in Bone
    10:30 AM - 11:00 AM
    Jason R. Stubbs, MD
  • Vitamin D Metabolites and the Gut Microbiome
    11:00 AM - 11:30 AM
    Deborah M. Kado, MD, MS 
  • Trimethylamine N-Oxide and Deoxycholic Acid: Risk Factors or Novel Therapeutic Targets in CKD
    11:30 AM - 12:00 PM
    Anna Jeanette Jovanovich, MD
  • Nicotinamide and Phosphate Homeostasis in CKD
    12:00 PM - 12:30 PM
    Joachim H. Ix, MD, FASN