Kidney Week

Basic/Clinical Science Session

New Participants in AKI: Cellular Components, Signaling, and More

November 08, 2019 | 02:00 PM - 04:00 PM

Location: 207, Walter E. Washington Convention Center

Session Description

AKI is conventionally regarded as the result of abnormalities in and interplay among the epithelial cell, the endothelial and other vascular cells, and inflammatory processes, along with abnormalities in renal energetics. This session presents new mechanisms and participants in AKI. These include processes arising in specific cellular compartments (lymphangiogenesis), involving specific cells (neutrophil extracellular traps), involving signaling in specific cells (interstitial fibroblasts), and originating from unexpected metabolic pathways (fructose metabolism).

Learning Objective(s)

• Describe the mechanisms of AKI
• Explain new pathways in AKI

Learning Pathway(s)

• Acute Kidney Injury

Moderators

• Subhashini Bolisetty, PhD
• Ambra Pozzi, PhD

Presentations

• The Role of Lymphangiogenesis
  02:00 PM - 02:30 PM
  Laurence Marie Black, PhD
  

  Laurence Marie Black, PhD

The Role of Lymphangiogenesis

November 08, 2019 | 02:00 PM - 02:30 PM

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• The Role of Neutrophil Extracellular Traps
  02:30 PM - 03:00 PM
  William Brian Reeves, MD, FASN
  

  William Brian Reeves, MD, FASN

The Role of Neutrophil Extracellular Traps

November 08, 2019 | 02:30 PM - 03:00 PM

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• The Role of Wnt/Beta-Catenin Signaling in Interstitial Fibroblasts
  03:00 PM - 03:30 PM
  Youhua Liu, PhD 
  
  

  Youhua Liu, PhD

  Dr. Youhua Liu is currently a Professor of Pathology and holds the UPMC Endowed Chair in tissue biology at the University of Pittsburgh. He obtained his PhD in cell biology from the Peking Union Medical College in Beijing, China. After his postdoctoral training at NIH, he joined the faculty of Brown University as an Assistant Professor of Medicine. He relocated to the University of Pittsburgh as an Associate Professor of Pathology and then a Professor of Pathology. Dr. Liu's research is focused on dissecting the cellular and molecular pathways that lead to kidney fibrosis, and exploring novel strategies for therapeutic intervention. Currently, his group is investigating several key signal pathways such as Wnt/beta-catenin and sonic hedgehog in the pathogenesis of kidney fibrosis, podocyte injury and proteinuria.

The Role of Wnt/Beta-Catenin Signaling in Interstitial Fibroblasts

November 08, 2019 | 03:00 PM - 03:30 PM

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• The Role of the Polyol Pathway
  03:30 PM - 04:00 PM
  Miguel A. Lanaspa, PhD, DVM
  

  Miguel A. Lanaspa, PhD, DVM

The Role of the Polyol Pathway

November 08, 2019 | 03:30 PM - 04:00 PM

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