Clinical Practice Session

Dysproteinemic Renal Disease

November 08, 2019 | 10:30 AM - 12:30 PM

Location: 201, Walter E. Washington Convention Center

Session Description

Dysproteinemia is associated with a diverse spectrum of renal conditions, the most established of which are light-chain cast nephropathy, light-chain deposition disease, and light-chain amyloidosis. This session focuses on clinical, pathologic, and pathophysiologic aspects of dysproteinemic renal disease, as well as the expanding spectrum of monoclonal gammopathy of renal significance.

Learning Objective(s)

  • Discuss new, more sensitive assays to detect circulating monoclonal proteins and implications for assessing outcomes
  • Identify the mechanisms by which monoclonal light chains induce damage to the kidney
  • Describe the latest findings in myeloma cast nephropathy
  • Explain how C3 glomerulopathy can be considered a form of monoclonal gammopathy of renal significance

Learning Pathway(s)

  • Pathology
  • Acute Kidney Injury


  • Samih H. Nasr, MD
  • Maria M. Picken, MD, PhD, FASN