Basic/Clinical Science Session

Basic Science Symposium - Organs-on-Chips: Human Kidney Microphysiological Systems

November 08, 2019 | 12:45 PM - 01:45 PM

Location: Marquis Ballroom, Salon 10, Marriott Marquis

Session Description

This session reviews the latest developments in using human "kidney-on-a-chip" in vitro microphyiological systems for understanding renal physiology, toxicology, disease modeling, and drug development.

Learning Objective(s)

  • Describe recent advances in organs-on-chips technologies for in vitro applications
  • Explain how human inducible pluripotent stem cells and cells from kidney organoids are now being incorporated into kidney organs-on-chips
  • Identify key challenges for both organoids and organs-on-chips, including scale, reproducibility, accuracy of cellular identity with respect to normal human tissue, physiological functions and readouts, and translational potential
  • Discuss how kidney-on-chip systems have utility for disease modeling and precision medicine applications

Learning Pathway(s)

  • Cell and Transport Physiology


  • Daniel Robert Gossett, PhD