The Kidney as a Sensor
October 25, 2020 | 02:30 PM - 04:30 PM
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Basic/Clinical Science Session
The Kidney as a Sensor
October 25, 2020 | 02:30 PM - 04:30 PM
Location: Simulive
Session Description
Recent studies have highlighted a role for the kidney as a sensor, often of metabolites or compounds from distant organs or sites. This session highlights the latest findings in this area and illustrates how the kidney acts as a sensor to help maintain homeostasis.
Learning Objective(s)
- Describe how the kidney acts as a sensor of gut microbial metabolites
- Discuss the role of receptors such as Oxgr1 (oxoglutarate receptor 1) in renal function
Learning Pathway(s)
- Cell and Transport Physiology
Moderators
- Jeff M. Sands, MD, FASN
- Blythe D. Shepard, PhD
Presentations
- Alpha-Ketoglutarate and Renal Function
02:30 PM - 03:00 PM
Paul A. Welling, MD
Alpha-Ketoglutarate and Renal Function
October 25, 2020 | 02:30 PM - 03:00 PM
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- Taste Receptors and Kidney Function
03:00 PM - 03:30 PM
Pablo A. Ortiz, PhD
Taste Receptors and Kidney Function
October 25, 2020 | 03:00 PM - 03:30 PM
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- The Kidney as a Sensor for Organic Anions
03:30 PM - 04:00 PM
Rosalinde Masereeuw, PhD
Rosalinde Masereeuw, PhD
Roos Masereeuw (UU) received her PhD from Radboud University in Nijmegen in January 1997. This PhD program and a postdoc period were partly performed at National Institute for Environmental Sciences (NIEHS/NIH), Research Triangle Park, NC, USA. Dr. Masereeuw also visited the NIEHS/NIH institute Mount Desert Island Biological Laboratory (ME, USA) as principal investigator in 1997, 1998, 2010 and 2014. In November 1996, she joined the Dept. of Pharmacology and Toxicology at Radboudumc as assistant professor and in July 2002, she was appointed as associate professor after obtaining an NWO-ASPASIA award. In 2009, she received the Dutch Pharmacological Society (NVF) Schering-Plough Pharmacology Award, in 2010 the Prix Galien Research Award and in 2015 she was elected Fellow of the American Association of Pharmaceutical Scientists. Since July 2015 she is full professor of Experimental Pharmacology and since November 2018 scientific director of Utrecht Institute for Pharmaceutical Sciences in The Netherlands. Research in the Masereeuw group is focused on developing novel therapeutic strategies to improve organ function in chronic disorders. Her group has developed unique human renal cell lines with a high predictive value for drug transport and metabolism. These cell lines are being used in the development of a bioartificial kidney, organotypic cultures for in vitro toxicity testing of chemical entities and drugs in development, and for studying the renal tubular secretion and reabsorption machinery. Roos Masereeuw has (co-)authored over 200 scientific papers, successfully supervised 21 PhD students and currently supervises 12 PhD students and 5 post-docs.
The Kidney as a Sensor for Organic Anions
October 25, 2020 | 03:30 PM - 04:00 PM
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- The Kidney as a Sensor for Butyrate
04:00 PM - 04:30 PM
Niels Olsen Saraiva Camara, MD, PhD
Niels Olsen Saraiva Camara, MD, PhD
Medical Doctor (Federal University of Ceara)
Nephrologist (Federal University of Sao Paulo)
Master and PhD on Nephrology (Federal University of Sao Paulo)
Post doc Imperial College London
Full Professor of Immunology at University of Sao Paulo
Full member of the Brazilian Academia of Sciences
Full member of the Sao Paulo State Academia of Sciences
The Kidney as a Sensor for Butyrate
October 25, 2020 | 04:00 PM - 04:30 PM
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