The Future of Dialysis: Bioengineering Tools to Improve Kidney Therapies
October 23, 2020 | 10:30 AM - 12:30 PM
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Translational Session
The Future of Dialysis: Bioengineering Tools to Improve Kidney Therapies
October 23, 2020 | 10:30 AM - 12:30 PM
Location: Live-Streamed
Session Description
Advanced CKD and ESKD are increasing worldwide, and these patients are afforded very few options for therapies besides traditional dialysis modalities. Because of kidney shortages, transplant wait times are extensive. Patients requiring hemodialysis often have dialysis vascular issues due to poor vasculature. This session discusses the role bioengineering can play in enhancing technologies and therapies to regenerate kidneys and kidney replacement therapies.
Learning Objective(s)
- Summarize recent innovations in bioartificial kidneys
- Discuss the history of kidney xenotransplantation and current progress
- Identify state-of-the-art techniques to regenerate kidneys
- Describe novel bioengineering technologies to improve blood vessels for dialysis vascular access
Learning Pathway(s)
- Dialysis
- Transplantation/Immunology
Moderators
- William Henry Fissell, MD
- Yan-Ting Elizabeth Shiu, PhD
Presentations
- Innovations and Advances in Wearable and Implantable Artificial Kidneys
10:30 AM - 11:00 AM
Shuvo Roy, PhD
Innovations and Advances in Wearable and Implantable Artificial Kidneys
October 23, 2020 | 10:30 AM - 11:00 AM
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- Clinical Pig Kidney Xenotransplantation: How Close Are We?
11:00 AM - 11:30 AM
David KC Cooper, MD, MA, MS, PhD
David KC Cooper, MD, MA, MS, PhD
DAVID K. C. COOPER, MA, PhD, MD, MS, DSc(Med), FRCS, FACS, FACC, FAST
Professor of Surgery and Co-Director, Xenotransplantation Program, University of Alabama at Birmingham
David Cooper studied medicine in the UK at Guy’s Hospital Medical School (now part of King’s College London), and trained in general and cardiothoracic surgery in Cambridge and London. Between 1972 and 1980, he was a Fellow and Director of Studies in Medical Sciences at Magdalene College, Cambridge. In 1980 he took up an appointment in cardiac surgery at the University of Cape Town where, under Professor Christiaan Barnard, he had responsibility for patients undergoing heart transplantation. In 1987, he relocated to the Oklahoma Transplantation Institute in the USA where he continued to work in both the clinical and research fields. After 17 years as a surgeon-scientist, he decided to concentrate on research, initially at the Massachusetts General Hospital/Harvard Medical School in Boston, subsequently at the University of Pittsburgh, and now at the University of Alabama at Birmingham (since 2016). His major interest is in developing cross-species transplantation with the aim of using pigs as sources of organs, cells, and corneas for transplantation in humans.
Clinical Pig Kidney Xenotransplantation: How Close Are We?
October 23, 2020 | 11:00 AM - 11:30 AM
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- Novel Advancements to Regenerate Kidneys: Regrow or Repair?
11:30 AM - 12:00 PM
Lauren Elizabeth Woodard, PhD
Lauren Elizabeth Woodard, PhD
Dr. Woodard is an Assistant Professor at Vanderbilt University Medical Center in the Department of Medicine, Division of Nephrology and Hypertension with a secondary appointment in the Department of Biomedical Engineering. Dr. Woodard received her Ph.D. from Stanford University followed by a postdoctoral fellowship at Baylor College of Medicine in the Division of Nephrology. Her research laboratory is focused on genome engineering of stem cells for kidney regeneration.
Novel Advancements to Regenerate Kidneys: Regrow or Repair?
October 23, 2020 | 11:30 AM - 12:00 PM
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- Bioengineered Blood Vessels for Arteriovenous Access: From the Bench to Clinical Trials
12:00 PM - 12:30 PM
Joris I. Rotmans, MD, PhD
Joris I. Rotmans, MD, PhD
Dr. Joris Rotmans is an internist-nephrologist and associate professor at the Department of Nephrology of the Leiden University Medical Center (LUMC) in the Netherlands. He received his PhD in 2005 at University of Amsterdam on new therapeutic strategies for vascular access for hemodialysis whereupon he started his residency in Internal Medicine. In 2008-2009, he did postdoctoral research on vascular tissue engineering at the Australian Institute of Bioengineering and Nanotechnology in Brisbane, Australia. Since 2010, he combines clinical work as internist-nephrologist with vascular and renal research at the Department of Nephrology of the LUMC Currently, dr. Rotmans is the chair of the Nephrology Residency Program at LUMC and the Expertise Center Vascular Access at the LUMC. He was the principle investigator of the DialysisXS consortium, in which a novel method to generate in vivo engineered blood vessels was developed. He was the principle investigator of the LIPMAT trial, a multicenter, randomized clinical trial in the Netherlands in which the efficacy of liposomal prednisolone to enhance AVF maturation is evaluated. He received a prestigious VIDI grant from NWO that allows him to expand his research group and to continue his research on vascular access for hemodialysis. Dr. Rotmans is board member of the Vascular Access Society and chair of the Thematic Working Group on Vascular Tissue Engineering of TERMIS.
Bioengineered Blood Vessels for Arteriovenous Access: From the Bench to Clinical Trials
October 23, 2020 | 12:00 PM - 12:30 PM
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