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ASN leads the fight to prevent, treat, and cure kidney diseases throughout the world by educating health professionals and scientists, advancing research and innovation, communicating new knowledge, and advocating for the highest quality care for patients.

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Kidney Week

Clinical Practice Session

The Who, What, and Where for SGLT2 Inhibitors in Diabetes

October 22, 2020 | 10:30 AM - 12:30 PM

Location: Live-Streamed

Session Description

Recent clinical trials show sodium-glucose cotransporter 2 (SGLT2) inhibitors have a significant effect on reducing risk of progressive renal decline as well as cardiovascular outcomes. These discoveries are changing the existing clinical protocols and leading to new, more effective interventions to care for patients with diabetes. In this session, experts in the field present the current trial results and discuss their clinical implications.

Learning Objective(s)

  • Describe the mechanisms of SGLT2
  • Discuss the controversies regarding whom SGLT2 mechanisms may not benefit
  • Summarize efficacy data for SGLT2 inhibitors on heart failure and related outcomes, the proposed mechanisms of this benefit, and the heterogeneity of effects on heart failure stratified by underlying diabetic kidney disease
  • Explain how potential adverse effects of SGLT2 inhibitors can be managed
  • Define strategies to optimize concurrent management of diabetes, kidney diseases, and heart disease

Learning Pathway(s)

  • Diabetes and Metabolism
  • Chronic Kidney Disease


  • Ian H. de Boer, MD, MS
  • Adeera Levin, MD


  • Kidney Protection with SGLT2 Inhibitors in Diabetes: Is It for Everyone?
    10:30 AM - 11:00 AM
    David Cherney, MD, PhD 
  • SGLT2 Inhibition for the Deadly Dyad of Diabetes: Heart Failure and Kidney Disease
    11:00 AM - 11:30 AM
    Matthew Cavender, MD, MPH
  • Adverse Effects of SGLT2 Inhibition in Advanced Diabetic Kidney Disease and How to Minimize Them
    11:30 AM - 12:00 PM
    Meg J. Jardine, MBBS, PhD 
  • Treating the Whole Person with Diabetic Kidney Disease: New Clinical Protocols
    12:00 PM - 12:30 PM
    Katherine R. Tuttle, MD, FASN